Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 28, 2011, Pages 11530-11535

  Dahirel, Vincent ^a,b,c   Shekhar, Karthik ^a,b   Pereyra, Florencia ^a   Miura, Toshiyuki ^h   Artyomov, Mikita ^c,d   Talsania, Shiv ^b,e   Allen, Todd M ^a   Altfeld, Marcus ^a   Carrington, Mary ^a,f   Irvine, Darrell J ^a,b,g   Walker, Bruce D ^a,g   Chakraborty, Arup K ^a,b,c  

^a HARVARD UNIVERSITY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d MOSCOW STATE UNIVERSITY   (Russian Federation)

^e LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^f SAIC FREDERICK INC   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cytotoxic T lymphocyte response; Elite controllers; Random matrix theory

Indexed keywords

GAG PROTEIN; VIRUS ANTIGEN;

ARTICLE; CYTOTOXIC T LYMPHOCYTE; GENETIC CONSERVATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; NUCLEOTIDE SEQUENCE; PHYSICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; PROTEIN STRUCTURE; VIRUS CAPSID; VIRUS MUTATION; VIRUS STRAIN;

CAPSID; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENES, GAG; GENES, VIRAL; HIV; HIV ANTIGENS; HIV INFECTIONS; HIV LONG-TERM SURVIVORS; HUMANS; IMMUNITY, CELLULAR; IMMUNODOMINANT EPITOPES; MODELS, MOLECULAR; MUTATION; PROTEIN MULTIMERIZATION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 79960999556     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105315108     Document Type: Article

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