-
1
-
-
56649114351
-
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: A case-cohort analysis
-
McElrath MJ, De Rosa SC, Moodie Z, et al. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 2008; 372:1894-05.
-
(2008)
Lancet
, vol.372
, pp. 1894-1905
-
-
McElrath, M.J.1
De Rosa, S.C.2
Moodie, Z.3
-
2
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder SP, Mehrotra DV, Duerr A, et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 2008; 372:1881-93.
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
-
3
-
-
58149136160
-
Post-step modifications for research on HIV vaccines
-
Corey L, McElrath MJ, Kublin JG. Post-step modifications for research on HIV vaccines. AIDS 2009; 23:3-8.
-
(2009)
AIDS
, vol.23
, pp. 3-8
-
-
Corey, L.1
McElrath, M.J.2
Kublin, J.G.3
-
4
-
-
56649111197
-
Failure of the Merck HIV vaccine: An uncertain step forward
-
Robb ML. Failure of the Merck HIV vaccine: an uncertain step forward. Lancet 2008; 372:1857-8.
-
(2008)
Lancet
, vol.372
, pp. 1857-1858
-
-
Robb, M.L.1
-
5
-
-
50849126803
-
HIV vaccine development in the aftermath of the STEP study: Re-focus on occult HIV infection?
-
Uberla K. HIV vaccine development in the aftermath of the STEP study: re-focus on occult HIV infection? PLoS Pathog 2008; 4:e1000114.
-
(2008)
PLoS Pathog
, vol.4
-
-
Uberla, K.1
-
6
-
-
44949100369
-
Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans
-
DOI 10.1038/nm.f.1759, PII NMF1759
-
Watkins DI, Burton DR, Kallas EG, Moore JP, Koff WC. Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans. Nat Med 2008; 14:617-21. (Pubitemid 351809543)
-
(2008)
Nature Medicine
, vol.14
, Issue.6
, pp. 617-621
-
-
Watkins, D.I.1
Burton, D.R.2
Kallas, E.G.3
Moore, J.P.4
Koff, W.C.5
-
8
-
-
38749096240
-
The failed HIV Merck vaccine study: A step back or a launching point for future vaccine development?
-
Sekaly RP. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J Exp Med 2008; 205:7-12.
-
(2008)
J Exp Med
, vol.205
, pp. 7-12
-
-
Sekaly, R.P.1
-
9
-
-
37549033167
-
One step forward, two steps back-will there ever be an AIDS vaccine?
-
Steinbrook R. One step forward, two steps back-will there ever be an AIDS vaccine? N Engl J Med 2007; 357:2653-5.
-
(2007)
N Engl J Med
, vol.357
, pp. 2653-2655
-
-
Steinbrook, R.1
-
10
-
-
38349151669
-
HIV-1 T-cell vaccines: Evaluating the next step
-
Pantaleo G. HIV-1 T-cell vaccines: evaluating the next step. Lancet Infect Dis 2008; 8:82-3.
-
(2008)
Lancet Infect Dis
, vol.8
, pp. 82-83
-
-
Pantaleo, G.1
-
11
-
-
76749115071
-
HIV-1 vaccine development after STEP
-
Barouch DH, Korber B. HIV-1 vaccine development after STEP. Annu Rev Med 2010; 61:153-67.
-
(2010)
Annu Rev Med
, vol.61
, pp. 153-167
-
-
Barouch, D.H.1
Korber, B.2
-
12
-
-
68349130410
-
Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells
-
Hutnick NA, Carnathan DG, Dubey SA, et al. Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells. Nat Med 2009; 15:876-8.
-
(2009)
Nat Med
, vol.15
, pp. 876-878
-
-
Hutnick, N.A.1
Carnathan, D.G.2
Dubey, S.A.3
-
13
-
-
68349135329
-
Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans
-
O'Brien KL, Liu J, King SL, et al. Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nat Med 2009; 15:873-5.
-
(2009)
Nat Med
, vol.15
, pp. 873-875
-
-
O'Brien, K.L.1
Liu, J.2
King, S.L.3
-
14
-
-
73949119632
-
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1
-
Benlahrech A, Harris J, Meiser A, et al. Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1. Proc Natl Acad Sci U S A 2009; 106:19940-5.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19940-19945
-
-
Benlahrech, A.1
Harris, J.2
Meiser, A.3
-
15
-
-
33846101731
-
+ T-cell responses to different HIV proteins have discordant associations with viral load
-
DOI 10.1038/nm1520, PII NM1520
-
Kiepiela P, Ngumbela K, Thobakgale C, et al. CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med 2007; 13:46-53. (Pubitemid 46067385)
-
(2007)
Nature Medicine
, vol.13
, Issue.1
, pp. 46-53
-
-
Kiepiela, P.1
Ngumbela, K.2
Thobakgale, C.3
Ramduth, D.4
Honeyborne, I.5
Moodley, E.6
Reddy, S.7
De Pierres, C.8
Mncube, Z.9
Mkhwanazi, N.10
Bishop, K.11
Van Der, S.M.12
Nair, K.13
Khan, N.14
Crawford, H.15
Payne, R.16
Leslie, A.17
Prado, J.18
Prendergast, A.19
Frater, J.20
McCarthy, N.21
Brander, C.22
Learn, G.H.23
Nickle, D.24
Rousseau, C.25
Coovadia, H.26
Mullins, J.I.27
Heckerman, D.28
Walker, B.D.29
Goulder, P.30
more..
-
16
-
-
43549109265
-
Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients
-
DOI 10.1084/jem.20072457
-
Goepfert PA, Lumm W, Farmer P, et al. Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients. J Exp Med 2008; 205:1009-17. (Pubitemid 351679677)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.5
, pp. 1009-1017
-
-
Goepfert, P.A.1
Lumm, W.2
Farmer, P.3
Matthews, P.4
Prendergast, A.5
Carlson, J.M.6
Derdeyn, C.A.7
Tang, J.8
Kaslow, R.A.9
Bansal, A.10
Yusim, K.11
Heckerman, D.12
Mulenga, J.13
Allen, S.14
Goulder, P.J.R.15
Hunter, E.16
-
17
-
-
58149267963
-
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
-
Liu J, O'Brien KL, Lynch DM, et al. Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 2009; 457:87-91.
-
(2009)
Nature
, vol.457
, pp. 87-91
-
-
Liu, J.1
O'Brien, K.L.2
Lynch, D.M.3
-
18
-
-
77949263061
-
Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys
-
Barouch DH, O'Brien KL, Simmons NL, et al. Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nat Med 2010; 16:319-23.
-
(2010)
Nat Med
, vol.16
, pp. 319-323
-
-
Barouch, D.H.1
O'Brien, K.L.2
Simmons, N.L.3
-
19
-
-
67449101823
-
Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge
-
Wilson NA, Keele BF, Reed JS, et al. Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge. J Virol 2009; 83:6508-21.
-
(2009)
J Virol
, vol.83
, pp. 6508-6521
-
-
Wilson, N.A.1
Keele, B.F.2
Reed, J.S.3
-
20
-
-
48749103238
-
Impact of MHC class I diversity on immune control of immunodeficiency virus replication
-
Goulder PJR, Watkins DI. Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat Rev Immunol 2008; 8:619-30.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 619-630
-
-
Goulder, P.J.R.1
Watkins, D.I.2
-
21
-
-
12144287434
-
Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection
-
DOI 10.1097/00002030-200312050-00005
-
Altfeld M, Addo MM, Rosenberg ES, et al. Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection. AIDS 2003; 17:2581-91. (Pubitemid 38402336)
-
(2003)
AIDS
, vol.17
, Issue.18
, pp. 2581-2591
-
-
Altfeld, M.1
Addo, M.M.2
Rosenberg, E.S.3
Hecht, F.M.4
Lee, P.K.5
Vogel, M.6
Yu, X.G.7
Draenert, R.8
Johnston, M.N.9
Strick, D.10
Allen, T.M.11
Feeney, M.E.12
Kahn, J.O.13
Sekaly, R.P.14
Levy, J.A.15
Rockstroh, J.K.16
Goulder, P.J.R.17
Walker, B.D.18
-
22
-
-
33750869972
-
HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8(+) T cell response against HIV-1
-
Altfeld M, Kalife ET, Qi Y, et al. HLA alleles associated with delayed progression to AIDS contribute strongly to the initial CD8(+) T cell response against HIV-1. PLoS Med 2006; 3:e403.
-
(2006)
PLoS Med
, vol.3
-
-
Altfeld, M.1
Kalife, E.T.2
Qi, Y.3
-
23
-
-
1842741699
-
HIV evolution: CTL escape mutation and reversion after transmission
-
DOI 10.1038/nm992
-
Leslie AJ, Pfafferott KJ, Chetty P, et al. HIV evolution: CTL escape mutation and reversion after transmission. Nat Med 2004; 10:282-9. (Pubitemid 38667619)
-
(2004)
Nature Medicine
, vol.10
, Issue.3
, pp. 282-289
-
-
Leslie, A.J.1
Pfafferott, K.J.2
Chetty, P.3
Draenert, R.4
Addo, M.M.5
Feeney, M.6
Tang, Y.7
Holmes, E.C.8
Allen, T.9
Prado, J.G.10
Altfeld, M.11
Brander, C.12
Dixon, C.13
Ramduth, D.14
Jeena, P.15
Thomas, S.A.16
St, J.A.17
Roach, T.A.18
Kupfer, B.19
Luzzi, G.20
Edwards, A.21
Taylor, G.22
Lyall, H.23
Tudor-Williams, G.24
Novelli, V.25
Martinez-Picado, J.26
Kiepiela, P.27
Walker, B.D.28
Goulder, P.J.R.29
more..
-
24
-
-
36048995423
-
Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A
-
DOI 10.1128/JVI.01369-07
-
Brockman MA, Schneidewind A, Lahaie M, et al. Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A. J Virol 2007; 81:12608-18. (Pubitemid 350085874)
-
(2007)
Journal of Virology
, vol.81
, Issue.22
, pp. 12608-12618
-
-
Brockman, M.A.1
Schneidewind, A.2
Lahaie, M.3
Schmidt, A.4
Miura, T.5
DeSouza, I.6
Ryvkin, F.7
Derdeyn, C.A.8
Allen, S.9
Hunter, E.10
Mulenga, J.11
Goepfert, P.A.12
Walker, B.D.13
Allen, T.M.14
-
25
-
-
67650924875
-
Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells
-
Streeck H, Jolin JS, Qi Y, et al. Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells. J Virol 2009; 83:7641-8.
-
(2009)
J Virol
, vol.83
, pp. 7641-7648
-
-
Streeck, H.1
Jolin, J.S.2
Qi, Y.3
-
26
-
-
27744456947
-
High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population
-
DOI 10.1007/s00251-005-0048-3
-
Itoh Y, Mizuki N, Shimada T, et al. High throughout DNA typing of HLA-A, -B, -C and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics 2005; 57:717-29. (Pubitemid 41598618)
-
(2005)
Immunogenetics
, vol.57
, Issue.10
, pp. 717-729
-
-
Itoh, Y.1
Mizuki, N.2
Shimada, T.3
Azuma, F.4
Itakura, M.5
Kashiwase, K.6
Kikkawa, E.7
Kulski, J.K.8
Satake, M.9
Inoko, H.10
-
28
-
-
33947420041
-
+ T-cell epitopes
-
DOI 10.1128/JVI.02689-06
-
Honeyborne I, Prendergast A, Pereyra F, et al. Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple Gag-specific CD8+ T-cell epitopes. J Virol 2007; 81:3667-72. (Pubitemid 46456679)
-
(2007)
Journal of Virology
, vol.81
, Issue.7
, pp. 3667-3672
-
-
Honeyborne, I.1
Prendergast, A.2
Pereyra, F.3
Leslie, A.4
Crawford, H.5
Payne, R.6
Reddy, S.7
Bishop, K.8
Moodley, E.9
Nair, K.10
Van Der, S.M.11
McCarthy, N.12
Rousseau, C.M.13
Addo, M.14
Mullins, J.I.15
Brander, C.16
Kiepiela, P.17
Walker, B.D.18
Goulder, P.J.R.19
-
29
-
-
74249086566
-
Common genetic variation and the control of HIV-1 in humans
-
Fellay J, Ge D, Shianna KV, et al. Common genetic variation and the control of HIV-1 in humans. PLoS Genet 2009; 5:e1000791.
-
(2009)
PLoS Genet
, vol.5
-
-
Fellay, J.1
Ge, D.2
Shianna, K.V.3
-
30
-
-
77956827161
-
Additive contribution of HLA class I alleles in the immune control of HIV-1 infection
-
in press, July 21st epub.
-
Leslie A, Matthews PC, Listgarten J, et al. Additive contribution of HLA class I alleles in the immune control of HIV-1 infection. J Virol 2010. in press, July 21st epub.
-
(2010)
J Virol
-
-
Leslie, A.1
Matthews, P.C.2
Listgarten, J.3
|