The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication

Nature Cell Biology

Volumn 13, Issue 8, 2011, Pages 1004-1009

  Puklowski, Anja ^a   Homsi, Yahya ^a   Keller, Debora ^b   May, Martin ^a   Chauhan, Sangeeta ^a   Kossatz, Uta ^a   Grünwald, Viktor ^a   Kubicka, Stefan ^a   Pich, Andreas ^a   Manns, Michael P ^a   Hoffmann, Ingrid ^c   Gönczy, Pierre ^b   Malek, Nisar P ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b EPFL   (Switzerland)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CELL PROTEIN; F BOX PROTEIN; POLO LIKE KINASE; POLO LIKE KINASE 4; PROTEIN FBXW5; PROTEIN HSSAS 6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DIVISION; CENTROSOME DUPLICATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REGULATORY MECHANISM; UBIQUITINATION;

CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CENTRIOLES; CENTROSOME; F-BOX PROTEINS; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SKP CULLIN F-BOX PROTEIN LIGASES; SUBSTRATE SPECIFICITY; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITIN-PROTEIN LIGASES;

EID: 79960990834     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2282     Document Type: Article

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