Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: A children's oncology group study

Clinical Cancer Research

Volumn 17, Issue 15, 2011, Pages 5113-5122

  DuBois, Steven G ^a   Shusterman, Suzanne ^b   Ingle, Ashish M ^c   Ahern, Charlotte H ^d   Reid, Joel M ^e   Wu, Bing ^f   Baruchel, Sylvain ^f   Glade Bender, Julia ^g   Ivy, Percy ^h   Grier, Holcombe E ^b   Adamson, Peter C ⁱ   Blaney, Susan M ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c CHILDREN S ONCOLOGY GROUP   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e Mayo Clinic   (United States)

^f HOSPITAL FOR SICK CHILDREN   (Canada)

^g Columbia University School of Medicine ^*  (United States)

^h NATIONAL CANCER INSTITUTE   (United States)

ⁱ UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUNITINIB;

ADOLESCENT; ADULT; ANEMIA; ANGIOGENESIS; ANOREXIA; ANTINEOPLASTIC ACTIVITY; ARTHRALGIA; ARTICLE; BICARBONATE BLOOD LEVEL; CARDIOTOXICITY; CENTRAL NERVOUS SYSTEM BLEEDING; CHILD; CLINICAL ARTICLE; CONSTIPATION; CRANIAL NEUROPATHY; DEHYDRATION; DIARRHEA; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG ERUPTION; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG METABOLISM; EPISTAXIS; EWING SARCOMA; EYE SWELLING; FATIGUE; FEMALE; GASTROINTESTINAL SYMPTOM; GLIOMA; HEART EJECTION FRACTION; HUMAN; HYPERMAGNESEMIA; HYPERNATREMIA; HYPERTENSION; HYPERURICEMIA; HYPOALBUMINEMIA; HYPOCALCEMIA; HYPONATREMIA; HYPOPHOSPHATEMIA; HYPOPIGMENTATION; HYPOTHYROIDISM; LEUKOPENIA; LYMPHOCYTOPENIA; MALE; MALIGNANT MENINGIOMA; MAXIMUM TOLERATED DOSE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; MYALGIA; NAUSEA; NEUROBLASTOMA; NEUTROPENIA; OSTEOSARCOMA; PHARMACODYNAMICS; PHASE 1 CLINICAL TRIAL; PRESCHOOL CHILD; PRIORITY JOURNAL; QT PROLONGATION; RECOMMENDED DRUG DOSE; REFRACTORY SOLID TUMOR; SCHOOL CHILD; SIDE EFFECT; SOFT TISSUE SARCOMA; SOLID TUMOR; SYSTOLIC DYSFUNCTION; THROMBOCYTOPENIA; VOMITING; WEIGHT REDUCTION;

ADOLESCENT; ADULT; ANTINEOPLASTIC AGENTS; CHILD; CHILD, PRESCHOOL; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, NEOPLASM; FEMALE; HEART; HUMANS; INDOLES; MALE; MAXIMUM TOLERATED DOSE; NEOPLASMS; NEUTROPENIA; PYRROLES;

EID: 79960983264     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-0237     Document Type: Article

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