메뉴 건너뛰기




Volumn 96, Issue 6, 2011, Pages 504-513

Heart failure with preserved ejection fraction: Fighting misconceptions for a new approach

Author keywords

Demographic aging; Heart failure therapy; Stroke volume; Ventricular function

Indexed keywords

ALDOSTERONE ANTAGONIST;

EID: 79960978741     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: 10.1590/S0066-782X2011000600012     Document Type: Review
Times cited : (21)

References (64)
  • 1
    • 53249090182 scopus 로고    scopus 로고
    • ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology
    • ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology.Eur Heart J. 2008; 29 (19): 2388-442.
    • (2008) Eur Heart J , vol.29 , Issue.19 , pp. 2388-2442
  • 2
    • 38849085186 scopus 로고    scopus 로고
    • Prognosis of heart failure with preserved ejection fraction:A 5 year prospective population-based study
    • 339-334
    • Tribouilloy C, Resinaru D, Mahjoub H, Souliére V, Levy F, Peltier M, et al. Prognosis of heart failure with preserved ejection fraction:a 5 year prospective population-based study. Eur Heart J. 2008; 29 (3): 339-4.
    • (2008) Eur Heart J , vol.29 , Issue.3
    • Tribouilloy, C.1    Resinaru, D.2    Mahjoub, H.3    Souliére, V.4    Levy, F.5    Peltier, M.6
  • 3
    • 33746033433 scopus 로고    scopus 로고
    • Outcome of heart failure with preserved ejection fraction in a population-based study
    • Bhatia RS, Tu J, Lee DS, Austin PC, Fang J, Haouzi A, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med. 2006; 355 (3): 260-9.
    • (2006) N Engl J Med , vol.355 , Issue.3 , pp. 260-269
    • Bhatia, R.S.1    Tu, J.2    Lee, D.S.3    Austin, P.C.4    Fang, J.5    Haouzi, A.6
  • 4
    • 34547837711 scopus 로고    scopus 로고
    • Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: A report from the OPTIMIZE-HF Registry
    • Fonarow GC, Stough WG, Abraham WT, Albert NM, Gheorghiade M, Greenberg BH, et al. Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry. J Am Coll Cardiol. 2007; 50 (8): 768-77.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.8 , pp. 768-777
    • Fonarow, G.C.1    Stough, W.G.2    Abraham, W.T.3    Albert, N.M.4    Gheorghiade, M.5    Greenberg, B.H.6
  • 5
    • 0037133660 scopus 로고    scopus 로고
    • New concepts in diastolic dysfunction and diastolic heart failure. Part I. Diagnosis, prognosis, and measurements of diastolic function
    • Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure. Part I. Diagnosis, prognosis, and measurements of diastolic function. Circulation. 2002; 105 (11): 1387-93.
    • (2002) Circulation , vol.105 , Issue.11 , pp. 1387-1393
    • Zile, M.R.1    Brutsaert, D.L.2
  • 6
  • 7
    • 29344440492 scopus 로고    scopus 로고
    • Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: A report from the ADHERE Database
    • Yancy CW, Lopatin M, Stevenson LW, De Marco T, Fonarow GC. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the ADHERE Database. J Am Coll Cardiol. 2006; 47 (1): 76-84.
    • (2006) J Am Coll Cardiol , vol.47 , Issue.1 , pp. 76-84
    • Yancy, C.W.1    Lopatin, M.2    Stevenson, L.W.3    de Marco, T.4    Fonarow, G.C.5
  • 9
    • 33748210723 scopus 로고    scopus 로고
    • Diastolic heart failure: A myth
    • Brutsaert DL, De Keulenaer. Diastolic heart failure: a myth. Curr Opin Cardiol. 2006; 21 (3): 240-8.
    • (2006) Curr Opin Cardiol , vol.21 , Issue.3 , pp. 240-248
    • Brutsaert, D.L.1    De, K.2
  • 10
    • 67649563195 scopus 로고    scopus 로고
    • The heart failure spectrum: Time for a phenotype-oriented approach
    • De Keulenaer GW, Brutsaert D. The heart failure spectrum: time for a phenotype-oriented approach. Circulation. 2009; 119 (24): 3044-6.
    • (2009) Circulation , vol.119 , Issue.24 , pp. 3044-3046
    • de Keulenaer, G.W.1    Brutsaert, D.2
  • 11
    • 0038523921 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction: Is this DHF?
    • Zille MR. Heart failure with preserved ejection fraction: is this DHF? J Am Coll Cardiol. 2003; 41 (9): 1519-22.
    • (2003) J Am Coll Cardiol , vol.41 , Issue.9 , pp. 1519-1522
    • Zille, M.R.1
  • 12
    • 67649497912 scopus 로고    scopus 로고
    • Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: Insights from the Framingham heart study of the NHLB Institute
    • Lee DS, Gona P, Vasan RS, Larson MB, Benjamin EJ, Wang TJ, et al. Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the Framingham heart study of the NHLB Institute. Circulation. 2009; 119 (24): 3070-7.
    • (2009) Circulation , vol.119 , Issue.24 , pp. 3070-3077
    • Lee, D.S.1    Gona, P.2    Vasan, R.S.3    Larson, M.B.4    Benjamin, E.J.5    Wang, T.J.6
  • 13
    • 0036776201 scopus 로고    scopus 로고
    • Diastolic heart failure in the community: Clinical profile, natural history, therapy, and impact of proposed diagnostic criteria
    • Chen HH, Lainchbury J, Senni M, Bailey KR, Redfield MM. Diastolic heart failure in the community: clinical profile, natural history, therapy, and impact of proposed diagnostic criteria. J Card Fail. 2002; 8 (5): 279-87.
    • (2002) J Card Fail , vol.8 , Issue.5 , pp. 279-287
    • Chen, H.H.1    Lainchbury, J.2    Senni, M.3    Bailey, K.R.4    Redfield, M.M.5
  • 14
    • 21244434236 scopus 로고    scopus 로고
    • Diastolic heart failure: Definitions and terminology
    • Zile MR, Baicu C, Bonnema DD, Diastolic heart failure: definitions and terminology. Prog Cardiovasc Dis. 2005; 47 (5): 307-13.
    • (2005) Prog Cardiovasc Dis , vol.47 , Issue.5 , pp. 307-313
    • Zile, M.R.1    Baicu, C.2    Bonnema, D.D.3
  • 15
    • 33646231760 scopus 로고    scopus 로고
    • Current perspectives in diastolic dysfunction and diastolic heart failure
    • Leite-Moreira AF. Current perspectives in diastolic dysfunction and diastolic heart failure. Heart. 2006; 92 (5): 712-8.
    • (2006) Heart , vol.92 , Issue.5 , pp. 712-718
    • Leite-Moreira, A.F.1
  • 16
    • 63149106905 scopus 로고    scopus 로고
    • The pathophysiology of heart failure with preserved ejection fraction and its therapeutic implications
    • Fontes-Carvalho R, Leite-Moreira AF. The pathophysiology of heart failure with preserved ejection fraction and its therapeutic implications. Rev Port Cardiol. 2009; 28 (1): 63-82.
    • (2009) Rev Port Cardiol , vol.28 , Issue.1 , pp. 63-82
    • Fontes-Carvalho, R.1    Leite-Moreira, A.F.2
  • 18
    • 64249155200 scopus 로고    scopus 로고
    • Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium
    • Borbély A, Falcao-Pires I, van Heerebeek L, Hamdani N, Edes I, Gavina C, et al. Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium. Circ Res. 2009; 104 (6): 780-6.
    • (2009) Circ Res , vol.104 , Issue.6 , pp. 780-786
    • Borbély, A.1    Falcao-Pires, I.2    van Heerebeek, L.3    Hamdani, N.4    Edes, I.5    Gavina, C.6
  • 19
    • 33646439273 scopus 로고    scopus 로고
    • Matrix metalloproteinases/tissue inhibitors of metalloproteinases: Relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease
    • Ahmed SH, Clark L, Pennington WR, Webb CS, Bonnema DD, Leonardi AH, et al. Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease.Circulation. 2006; 113 (17): 2089-96.
    • (2006) Circulation , vol.113 , Issue.17 , pp. 2089-2096
    • Ahmed, S.H.1    Clark, L.2    Pennington, W.R.3    Webb, C.S.4    Bonnema, D.D.5    Leonardi, A.H.6
  • 20
    • 0034680366 scopus 로고    scopus 로고
    • A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure
    • Spinale FG, Coker M., Heung LJ, Bond BR, Gunasinghe HR, Etoht, et al. A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation. 2000; 102 (16): 1944-9.
    • (2000) Circulation , vol.102 , Issue.16 , pp. 1944-1949
    • Spinale, F.G.1    Coker, M.2    Heung, L.J.3    Bond, B.R.4    Gunasinghe, H.R.5    Etoht6
  • 21
    • 39649109423 scopus 로고    scopus 로고
    • Molecular basis of diastolic dysfunction
    • Periasamy M, Jansen P. Molecular basis of diastolic dysfunction. Heart Fail Clin. 2008; 4 (1): 13-21.
    • (2008) Heart Fail Clin , vol.4 , Issue.1 , pp. 13-21
    • Periasamy, M.1    Jansen, P.2
  • 22
    • 63849177462 scopus 로고    scopus 로고
    • Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. A Report of the ACC Foundation/AHA Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation
    • Hunt SA, Abraham W, Chin MH, Feldman AM, Francis S, Ganiats TG, et al. 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. A Report of the ACC Foundation/AHA Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation.J Am Coll Cardiol, 2009; 53 (15): e1-e90.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.15
    • Hunt, S.A.1    Abraham, W.2    Chin, M.H.3    Feldman, A.M.4    Francis, S.5    Ganiats, T.G.6
  • 23
    • 3843094224 scopus 로고    scopus 로고
    • Diastolic heart failure: Abnormalities in active relaxation and passive stiffness of the left ventricle
    • Zile MR, Baicu C, Gaasch WH. Diastolic heart failure: abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med. 2004; 19 (19): 1953-9.
    • (2004) N Engl J Med , vol.19 , Issue.19 , pp. 1953-1959
    • Zile, M.R.1    Baicu, C.2    Gaasch, W.H.3
  • 24
    • 34548525319 scopus 로고    scopus 로고
    • How to diagnose diastolic heart failure: A consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology
    • Paulus W, Tchoppe C, Sanderson J, Rusconi C, Flachskampf FE, Rademakers FE, et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J. 2007; 28 (20): 2539-50.
    • (2007) Eur Heart J , vol.28 , Issue.20 , pp. 2539-2550
    • Paulus, W.1    Tchoppe, C.2    Sanderson, J.3    Rusconi, C.4    Flachskampf, F.E.5    Rademakers, F.E.6
  • 25
    • 0037425535 scopus 로고    scopus 로고
    • Burden of systolic and diastolic ventricular dysfunction in the community: Appreciating the scope of the heart failure epidemic
    • Redfield MM, Jacobsen S, Burnett JC Jr, Mahoney DW, Bailey KR, Rodeheffer RJ. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003; 289 (2): 194-202.
    • (2003) JAMA , vol.289 , Issue.2 , pp. 194-202
    • Redfield, M.M.1    Jacobsen, S.2    Burnett Jr., J.C.3    Mahoney, D.W.4    Bailey, K.R.5    Rodeheffer, R.J.6
  • 26
    • 70349313206 scopus 로고    scopus 로고
    • Prevalence of left ventricular diastolic dysfunction in a general population
    • Kuznetsova T, Herbotz L, Lopez B, Jin Y, Richart T, Thys L, et al. Prevalence of left ventricular diastolic dysfunction in a general population. Circ Heart Fail. 2009; 2 (2): 105-12.
    • (2009) Circ Heart Fail , vol.2 , Issue.2 , pp. 105-112
    • Kuznetsova, T.1    Herbotz, L.2    Lopez, B.3    Jin, Y.4    Richart, T.5    Thys, L.6
  • 27
    • 16244402639 scopus 로고    scopus 로고
    • Left heart failure with a normal ejection fraction: Identification of different pathophysiologic mechanisms
    • Maurer MS, King D, El-Khoury R, Packer M, Burkhoff D. Left heart failure with a normal ejection fraction: identification of different pathophysiologic mechanisms. J Card Fail. 2005; 11 (3): 177-87.
    • (2005) J Card Fail , vol.11 , Issue.3 , pp. 177-187
    • Maurer, M.S.1    King, D.2    El-Khoury, R.3    Packer, M.4    Burkhoff, D.5
  • 28
    • 61549090009 scopus 로고    scopus 로고
    • Heart failure with normal left ventricular ejection fraction
    • Maeder M, Kaye D, Heart failure with normal left ventricular ejection fraction. J Am Coll Cardiol. 2009; 53 (11): 905-18.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.11 , pp. 905-918
    • Maeder, M.1    Kaye, D.2
  • 29
    • 0037432184 scopus 로고    scopus 로고
    • Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: Implications for systolic and diastolic reserve limitations
    • Kawaguchi M, Hay I, Fetics B, Kass DA. Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic reserve limitations. Circulation. 2003; 107 (5): 714-20.
    • (2003) Circulation , vol.107 , Issue.5 , pp. 714-720
    • Kawaguchi, M.1    Hay, I.2    Fetics, B.3    Kass, D.A.4
  • 30
    • 39649106311 scopus 로고    scopus 로고
    • Ventricular-vascular interaction in heart failure
    • Borlaug BA, Kass DA. Ventricular-vascular interaction in heart failure. Heart Fail Clin. 2008; 4 (1): 23-36.
    • (2008) Heart Fail Clin , vol.4 , Issue.1 , pp. 23-36
    • Borlaug, B.A.1    Kass, D.A.2
  • 31
    • 33750995868 scopus 로고    scopus 로고
    • Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction
    • Borlaug BA, Melenovski V, Russell SD, Kessler K, Pacak K, Becker LC, et al. Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. Circulation. 2006; 114 (20): 2138-47.
    • (2006) Circulation , vol.114 , Issue.20 , pp. 2138-2147
    • Borlaug, B.A.1    Melenovski, V.2    Russell, S.D.3    Kessler, K.4    Pacak, K.5    Becker, L.C.6
  • 32
    • 33847316480 scopus 로고    scopus 로고
    • Ventricular structure and function in hypertensive participants with heart failure and a normal ejection fraction: The Cardiovascular Health Study
    • Maurer MS, Burkhoff D, Fried LP, Gottdiener J, King DL, Kitzman DW. Ventricular structure and function in hypertensive participants with heart failure and a normal ejection fraction: the Cardiovascular Health Study. J Am Coll Cardiol. 2007; 49 (9): 972-81.
    • (2007) J Am Coll Cardiol , vol.49 , Issue.9 , pp. 972-981
    • Maurer, M.S.1    Burkhoff, D.2    Fried, L.P.3    Gottdiener, J.4    King, D.L.5    Kitzman, D.W.6
  • 33
    • 44449100711 scopus 로고    scopus 로고
    • Preserved left ventricular twist and circumferential deformation, but depressed longitudinal and radial deformation in patients with diastolic heart failure
    • Wang J, Khoury D, Yue Y, Torre-Amione G, Nagueh SF. Preserved left ventricular twist and circumferential deformation, but depressed longitudinal and radial deformation in patients with diastolic heart failure. Eur Heart J. 2008; 29 (10): 1283-9.
    • (2008) Eur Heart J , vol.29 , Issue.10 , pp. 1283-1289
    • Wang, J.1    Khoury, D.2    Yue, Y.3    Torre-Amione, G.4    Nagueh, S.F.5
  • 34
    • 67449092157 scopus 로고    scopus 로고
    • The pathophysiology of heart failure with normal ejection fraction: Exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion
    • Tan YT, Wenzelburger F, Lee E, Heatlie G, Leyva F, Patel K, et al. The pathophysiology of heart failure with normal ejection fraction: exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion. J Am Coll Cardiol. 2009; 54 (10): 36-46.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.10 , pp. 36-46
    • Tan, Y.T.1    Wenzelburger, F.2    Lee, E.3    Heatlie, G.4    Leyva, F.5    Patel, K.6
  • 35
    • 42449100055 scopus 로고    scopus 로고
    • Role of left ventricular stiffness in heart failure with normal ejection fraction
    • Westermann D, Kasner M, Steendijk P, Spillmann F, Riead A, Weitmann K, et al. Role of left ventricular stiffness in heart failure with normal ejection fraction. Circulation. 2008; 117 (16): 2051-60.
    • (2008) Circulation , vol.117 , Issue.16 , pp. 2051-2060
    • Westermann, D.1    Kasner, M.2    Steendijk, P.3    Spillmann, F.4    Riead, A.5    Weitmann, K.6
  • 36
    • 0025727274 scopus 로고
    • Exercise intolerance in patients with heart failure and preserved left ventricular systolic function: Failure of the Frank-Starling mechanism
    • Kitzman DW, Higginbotham M, Cobb FR, Sheikh KH, Sullivan MJ. Exercise intolerance in patients with heart failure and preserved left ventricular systolic function: failure of the Frank-Starling mechanism. J Am Coll Cardiol. 1991; 17 (5): 1065-72.
    • (1991) J Am Coll Cardiol , vol.17 , Issue.5 , pp. 1065-1072
    • Kitzman, D.W.1    Higginbotham, M.2    Cobb, F.R.3    Sheikh, K.H.4    Sullivan, M.J.5
  • 37
    • 0141752959 scopus 로고    scopus 로고
    • Doppler tissue analysis of mitral annular velocities: Evidence for systolic abnormalities in patients with diastolic heart failure
    • Bruch C, Gradaus R, Gunia S, Breithardt G, Wichter T. Doppler tissue analysis of mitral annular velocities: evidence for systolic abnormalities in patients with diastolic heart failure. J Am Soc Echocardiogr. 2003; 16 (10): 1031-6.
    • (2003) J Am Soc Echocardiogr , vol.16 , Issue.10 , pp. 1031-1036
    • Bruch, C.1    Gradaus, R.2    Gunia, S.3    Breithardt, G.4    Wichter, T.5
  • 38
    • 0036153340 scopus 로고    scopus 로고
    • Left ventricular long axis function in diastolic heart failure is reduced in both diastole and systole: Time for a redefinition?
    • Yip G, Wang M, Zhang Y, Fung JW, Ho PY, Sanderson JE. Left ventricular long axis function in diastolic heart failure is reduced in both diastole and systole: time for a redefinition? Heart Fail Clin. 2002; 87 (2): 121-5.
    • (2002) Heart Fail Clin , vol.87 , Issue.2 , pp. 121-125
    • Yip, G.1    Wang, M.2    Zhang, Y.3    Fung, J.W.4    Ho, P.Y.5    Sanderson, J.E.6
  • 39
    • 62449330865 scopus 로고    scopus 로고
    • Recommendations for the evaluation of left ventricular diastolic function by echocardiography
    • Nagueh SF, Appleton C, Gillebert TC, Marino PN, Oh JK, Smiseth AO, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. Eur J Echocardiogr. 2009; 10 (2): 165-93.
    • (2009) Eur J Echocardiogr , vol.10 , Issue.2 , pp. 165-193
    • Nagueh, S.F.1    Appleton, C.2    Gillebert, T.C.3    Marino, P.N.4    Oh, J.K.5    Smiseth, A.O.6
  • 40
    • 70350714038 scopus 로고    scopus 로고
    • Heart failure with normal ejection fraction: New diagnostic criteria and pathophysiological advances
    • Mesquita E, Jorge A. Heart failure with normal ejection fraction: new diagnostic criteria and pathophysiological advances. Arq Bras Cardiol. 2009; 93 (2): 180-7.
    • (2009) Arq Bras Cardiol , vol.93 , Issue.2 , pp. 180-187
    • Mesquita, E.1    Jorge, A.2
  • 41
    • 34250846408 scopus 로고    scopus 로고
    • Restrictive filling pattern is a powerful predictor of heart failure events post acute myocardial infarction and in established heart failure: A literature-based meta-analysis
    • Somaratne JB, Whalley G, Gamble GD, Doughty R. Restrictive filling pattern is a powerful predictor of heart failure events post acute myocardial infarction and in established heart failure: a literature-based meta-analysis. J Card Fail. 2007; 13 (5): 346-52.
    • (2007) J Card Fail , vol.13 , Issue.5 , pp. 346-352
    • Somaratne, J.B.1    Whalley, G.2    Gamble, G.D.3    Doughty, R.4
  • 42
    • 70349307069 scopus 로고    scopus 로고
    • Echocardiographic evaluation of diastolic function can be used to guide clinical care
    • Little WC, Oh J. Echocardiographic evaluation of diastolic function can be used to guide clinical care. Circulation. 2009; 120 (9): 802-9.
    • (2009) Circulation , vol.120 , Issue.9 , pp. 802-809
    • Little, W.C.1    Oh, J.2
  • 44
    • 0141504294 scopus 로고    scopus 로고
    • The left atrium: A biomarker of chronic diastolic dysfunction and cardiovascular disease risk
    • Douglas P. The left atrium: a biomarker of chronic diastolic dysfunction and cardiovascular disease risk. J Am Coll Cardiol. 2003; 42 (7): 1206-7.
    • (2003) J Am Coll Cardiol , vol.42 , Issue.7 , pp. 1206-1207
    • Douglas, P.1
  • 45
    • 42749090179 scopus 로고    scopus 로고
    • Usefulness of new diastolic strain and strain rate indexes for the estimation of left ventricular filling pressure
    • Dokainish H, Sengupta R, Pillai M, Bobek J, Lakkis N. Usefulness of new diastolic strain and strain rate indexes for the estimation of left ventricular filling pressure. Am J Cardiol. 2008; 101 (10): 1504-9.
    • (2008) Am J Cardiol , vol.101 , Issue.10 , pp. 1504-1509
    • Dokainish, H.1    Sengupta, R.2    Pillai, M.3    Bobek, J.4    Lakkis, N.5
  • 46
    • 11144239323 scopus 로고    scopus 로고
    • Diastolic stress echocardiography: A novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography
    • Ha JW, Oh JK, Pellikka PA, Ommen SR, Stussy VL, Bailey KR, et al. Diastolic stress echocardiography: a novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography. J Am Soc Echocardiogr. 2005; 18 (1): 63-8.
    • (2005) J Am Soc Echocardiogr , vol.18 , Issue.1 , pp. 63-68
    • Ha, J.W.1    Oh, J.K.2    Pellikka, P.A.3    Ommen, S.R.4    Stussy, V.L.5    Bailey, K.R.6
  • 47
    • 70349331277 scopus 로고    scopus 로고
    • Is echocardiographic evaluation of diastolic function useful in determining clinical care? Doppler echocardiography yields dubious estimates of left ventricular diastolic pressures
    • Tschöpe C, Paulus W. Is echocardiographic evaluation of diastolic function useful in determining clinical care? Doppler echocardiography yields dubious estimates of left ventricular diastolic pressures. Circulation. 2009; 120 (9): 810-20.
    • (2009) Circulation , vol.120 , Issue.9 , pp. 810-820
    • Tschöpe, C.1    Paulus, W.2
  • 48
    • 33748988737 scopus 로고    scopus 로고
    • PEP-CHF Investigators. The perindopril in elderly people with chronic heart failure (PEP-CHF) study
    • Cleland JG, Tendera M, Adamus J, Freemantle N, Polonski L, Taylor I. PEP-CHF Investigators. The perindopril in elderly people with chronic heart failure (PEP-CHF) study. Eur Heart J. 2006; 27 (19): 2338-45.
    • (2006) Eur Heart J , vol.27 , Issue.19 , pp. 2338-2345
    • Cleland, J.G.1    Tendera, M.2    Adamus, J.3    Freemantle, N.4    Polonski, L.5    Taylor, I.6
  • 49
    • 57349142933 scopus 로고    scopus 로고
    • I-PRESERVE Investigators. Irbesartan in patients with heart failure and preserved ejection fraction
    • Massie BM, Carson P, McMurray JJ, Komajda M, McKelvie R, Zile MR. I-PRESERVE Investigators. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med. 2008; 359 (23): 2456-67.
    • (2008) N Engl J Med , vol.359 , Issue.23 , pp. 2456-2467
    • Massie, B.M.1    Carson, P.2    McMurray, J.J.3    Komajda, M.4    McKelvie, R.5    Zile, M.R.6
  • 50
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARM-Preserved Trial
    • Yusuf S, Pfeffer M, Swedberg K, Granger CB, Held P, McMurray JJ, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003; 362 (9386): 777-81.
    • (2003) Lancet , vol.362 , Issue.9386 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    McMurray, J.J.6
  • 51
    • 33847320614 scopus 로고    scopus 로고
    • Prescription of beta-blockers in patients with advanced heart failure and preserved left ventricular ejection fraction: Clinical implications and survival
    • Dobre D, van Veldhuisen D, DeJongste MJ, Lucas C, Cleuren G, Sanderman R, et al. Prescription of beta-blockers in patients with advanced heart failure and preserved left ventricular ejection fraction: clinical implications and survival. Eur J Heart Fail. 2007; 9 (3): 280-6.
    • (2007) Eur J Heart Fail , vol.9 , Issue.3 , pp. 280-286
    • Dobre, D.1    van Veldhuisen, D.2    Dejongste, M.J.3    Lucas, C.4    Cleuren, G.5    Sanderman, R.6
  • 52
    • 66149123458 scopus 로고    scopus 로고
    • SENIORS Investigators. Beta-blockade with nebivolol in elderly heart failure patients with impaired and preserved left ventricular ejection fraction: Data from SENIORS
    • van Veldhuisen DJ, Cohen-Solal A, Böhm M, Anker SD, Babalis D, Roughton M, et al. SENIORS Investigators. Beta-blockade with nebivolol in elderly heart failure patients with impaired and preserved left ventricular ejection fraction: data from SENIORS. J Am Coll Cardiol. 2009; 53 (23): 2150-8.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.23 , pp. 2150-2158
    • van Veldhuisen, D.J.1    Cohen-Solal, A.2    Böhm, M.3    Anker, S.D.4    Babalis, D.5    Roughton, M.6
  • 53
    • 0035818917 scopus 로고    scopus 로고
    • Aldosterone in congestive heart failure
    • Weber KT. Aldosterone in congestive heart failure. N Engl J Med. 2001; 345 (23): 1689-97.
    • (2001) N Engl J Med , vol.345 , Issue.23 , pp. 1689-1697
    • Weber, K.T.1
  • 54
    • 3543099842 scopus 로고    scopus 로고
    • Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure
    • Mottram PM, Haluska B, Leano R, Cowley D, Stowasser M, Marwick TH. Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure. Circulation. 2004; 110 (5): 558-65.
    • (2004) Circulation , vol.110 , Issue.5 , pp. 558-565
    • Mottram, P.M.1    Haluska, B.2    Leano, R.3    Cowley, D.4    Stowasser, M.5    Marwick, T.H.6
  • 55
    • 16244371321 scopus 로고    scopus 로고
    • The effect of alagebrium chloride (ALT-711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure
    • Little WC, Zile M, Kitzman DW, Hundley WG, ÓBrien TX, Degroof RC. The effect of alagebrium chloride (ALT-711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure. J Card Fail. 2005; 11 (3): 191-5.
    • (2005) J Card Fail , vol.11 , Issue.3 , pp. 191-195
    • Little, W.C.1    Zile, M.2    Kitzman, D.W.3    Hundley, W.G.4    ÓBrien, T.X.5    Degroof, R.C.6
  • 56
    • 33947606366 scopus 로고    scopus 로고
    • Drug discovery for heart failure: A new era or the end of the pipeline?
    • Kaye DM, Krum H. Drug discovery for heart failure: a new era or the end of the pipeline? Nat Rev Drug Discov. 2007; 6 (2): 127-39.
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.2 , pp. 127-139
    • Kaye, D.M.1    Krum, H.2
  • 58
    • 0037377630 scopus 로고    scopus 로고
    • ET-1 increases distensibility of acutely loaded myocardium: A novel ETA and Na+/H+ exchanger mediated effect
    • Leite-Moreira AF, Bras-Silva C, Pedrosa CA, Rocha-Sousa AA. ET-1 increases distensibility of acutely loaded myocardium: a novel ETA and Na+/H+ exchanger mediated effect. Am J Physiol Heart Circ Physiol. 2003; 284 (4): 1332-9.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , Issue.4 , pp. 1332-1339
    • Leite-Moreira, A.F.1    Bras-Silva, C.2    Pedrosa, C.A.3    Rocha-Sousa, A.A.4
  • 59
    • 65649094804 scopus 로고    scopus 로고
    • Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart
    • Castro-Chaves P, Fontes-Carvalho R, Pintalhao M, Pimentel-Nunes P, Leite- Moreira AF. Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart. Exp Physiol. 2009; 94 (6): 665-74.
    • (2009) Exp Physiol , vol.94 , Issue.6 , pp. 665-674
    • Castro-Chaves, P.1    Fontes-Carvalho, R.2    Pintalhao, M.3    Pimentel-Nunes, P.4    Leite-Moreira, A.F.5
  • 61
    • 39649109423 scopus 로고    scopus 로고
    • Molecular basis of diastolic dysfunction
    • Periasamy M, Jansen PM. Molecular basis of diastolic dysfunction. Heart. Fail Clin. 2008; 4 (1): 13-21.
    • (2008) Heart Fail Clin , vol.4 , Issue.1 , pp. 13-21
    • Periasamy, M.1    Jansen, P.M.2
  • 62
    • 40149084622 scopus 로고    scopus 로고
    • Improved exercise capacity and reduced systemic inflammation after adenoviralmediated SERCA-2a gene transfer
    • Gupta D, Palma J, Molina E, Gaughan JP, Long W, Houser S, et al. Improved exercise capacity and reduced systemic inflammation after adenoviralmediated SERCA-2a gene transfer. J Surg Res. 2008; 145 (2): 257-65.
    • (2008) J Surg Res , vol.145 , Issue.2 , pp. 257-265
    • Gupta, D.1    Palma, J.2    Molina, E.3    Gaughan, J.P.4    Long, W.5    Houser, S.6
  • 63
    • 0034701045 scopus 로고    scopus 로고
    • Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase
    • Schmidt U, del Monte F, Miyamoto MI, Matsui T, Gwathmey JK, Rosenzweig A, et al. Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. Circulation. 2000; 101 (7): 790-6.
    • (2000) Circulation , vol.101 , Issue.7 , pp. 790-796
    • Schmidt, U.1    del Monte, F.2    Miyamoto, M.I.3    Matsui, T.4    Gwathmey, J.K.5    Rosenzweig, A.6
  • 64
    • 36148932890 scopus 로고    scopus 로고
    • Type 5 Phosphodiesterase inhibition in heart failure: The next step
    • Goldsmith SR. Type 5 Phosphodiesterase inhibition in heart failure: the next step. J Am Coll Cardiol. 2007; 50 (22): 2145-7.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.22 , pp. 2145-2147
    • Goldsmith, S.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.