Mangiferin attenuates methylmercury induced cytotoxicity against IMR-32, human neuroblastoma cells by the inhibition of oxidative stress and free radical scavenging potential

Chemico-Biological Interactions

Volumn 193, Issue 2, 2011, Pages 129-140

  Das, Shubhankar ^a   Nageshwar Rao, B ^a   Satish Rao, B S ^a  

^a MANIPAL UNIVERSITY   (India)

Author keywords

Apoptosis; Genotoxicity; Mangiferin; Methylmercury; Neurotoxicity

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CYTOCHROME C; FLUORESCEIN ISOTHIOCYANATE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LIPOCORTIN 5; MALONALDEHYDE; MANGIFERIN; MELATONIN 1 RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SCAVENGER; TUBULIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ASSAY; CELL MEMBRANE DEPOLARIZATION; CELL PROTECTION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DETERMINATION; DNA FRAGMENTATION; DRUG DETERMINATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MICRONUCLEUS; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANNEXIN A5; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CASPASE 3; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; COMET ASSAY; CYTOCHROMES C; CYTOKINESIS; CYTOPROTECTION; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FREE RADICAL SCAVENGERS; HUMANS; INHIBITORY CONCENTRATION 50; INTRACELLULAR SPACE; MEMBRANE POTENTIAL, MITOCHONDRIAL; METALLOTHIONEIN; METHYLMERCURY COMPOUNDS; MICRONUCLEUS TESTS; NECROSIS; NEUROBLASTOMA; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; TUBULIN; TUBULIN MODULATORS; TUMOR STEM CELL ASSAY; XANTHONES;

EID: 79960976005     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.06.002     Document Type: Article

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