메뉴 건너뛰기




Volumn 32, Issue 8, 2011, Pages 487-494

Pharmacogenomics and cancer stem cells: A changing landscape?

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; DICKKOPF 1 PROTEIN; DOXORUBICIN; GAMMA SECRETASE; IMATINIB; INTERLEUKIN 6; IRINOTECAN; NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 79960966714     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2011.03.010     Document Type: Review
Times cited : (20)

References (79)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0035689738 scopus 로고    scopus 로고
    • Drug resistance in cancer: A perspective
    • DOI 10.1023/A:1013164609041
    • J.H. Goldie Drug resistance in cancer: a perspective Cancer Metastasis Rev. 20 2001 63 68 (Pubitemid 34074680)
    • (2001) Cancer and Metastasis Reviews , vol.20 , Issue.1-2 , pp. 63-68
    • Goldie, J.H.1
  • 3
    • 33745876823 scopus 로고    scopus 로고
    • TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy?
    • DOI 10.1016/j.tips.2006.06.007, PII S0165614706001556
    • M.L. Maitland TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy? Trends Pharmacol. Sci. 27 2006 432 437 (Pubitemid 44051569)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.8 , pp. 432-437
    • Maitland, M.L.1    Vasisht, K.2    Ratain, M.J.3
  • 4
    • 43749114271 scopus 로고    scopus 로고
    • Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: A prospective clinical trial by the German 5-FU Toxicity Study Group
    • M. Schwab Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group J. Clin. Oncol. 26 2008 2131 2138
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2131-2138
    • Schwab, M.1
  • 5
    • 60149109533 scopus 로고    scopus 로고
    • Looking ahead in cancer stem cell research
    • J.E. Dick Looking ahead in cancer stem cell research Nat. Biotechnol. 27 2009 44 46
    • (2009) Nat. Biotechnol. , vol.27 , pp. 44-46
    • Dick, J.E.1
  • 6
    • 77953143517 scopus 로고    scopus 로고
    • Glioma cell populations grouped by different cell type markers drive brain tumor growth
    • L. Prestegarden Glioma cell populations grouped by different cell type markers drive brain tumor growth Cancer Res. 70 2010 4274 4279
    • (2010) Cancer Res. , vol.70 , pp. 4274-4279
    • Prestegarden, L.1
  • 7
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • DOI 10.1038/nrc1590
    • M. Dean Tumour stem cells and drug resistance Nat. Rev. Cancer 5 2005 275 284 (Pubitemid 40488633)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 8
    • 0001491686 scopus 로고
    • Historical structure of scientific discovery
    • T.S. Kuhn Historical structure of scientific discovery Science 136 1962 760 764
    • (1962) Science , vol.136 , pp. 760-764
    • Kuhn, T.S.1
  • 9
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • DOI 10.1038/nm0797-730
    • D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat. Med. 3 1997 730 737 (Pubitemid 27298715)
    • (1997) Nature Medicine , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 10
    • 48349133869 scopus 로고    scopus 로고
    • Side population cells in human cancers
    • C. Wu, and B.A. Alman Side population cells in human cancers Cancer Lett. 268 2008 1 9
    • (2008) Cancer Lett. , vol.268 , pp. 1-9
    • Wu, C.1    Alman, B.A.2
  • 11
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • DOI 10.1158/0008-5472.CAN-06-3557
    • M.M. Ho Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells Cancer Res. 67 2007 4827 4833 (Pubitemid 46910191)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 13
    • 79953006501 scopus 로고    scopus 로고
    • Side Population is not Necessary or Sufficient for a Cancer Stem Cell Phenotype in Glioblastoma Multiforme
    • doi:10.1002/stem.582
    • Broadley, K.W. et al. Side Population is not Necessary or Sufficient for a Cancer Stem Cell Phenotype in Glioblastoma Multiforme. Stem Cells, doi:10.1002/stem.582.
    • Stem Cells
    • Broadley, K.W.1
  • 16
    • 49149107236 scopus 로고    scopus 로고
    • Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
    • S.J. Dylla Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy PLoS ONE 3 2008 e2428
    • (2008) PLoS ONE , vol.3 , pp. 2428
    • Dylla, S.J.1
  • 18
    • 73349112868 scopus 로고    scopus 로고
    • Targeting prostate cancer stem cells
    • F. Crea Targeting prostate cancer stem cells Anticancer Agents Med. Chem. 9 2009 1105 1113
    • (2009) Anticancer Agents Med. Chem. , vol.9 , pp. 1105-1113
    • Crea, F.1
  • 19
    • 18944375734 scopus 로고    scopus 로고
    • Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
    • G. Dontu Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells Breast Cancer Res. 6 2004 R605 615
    • (2004) Breast Cancer Res. , vol.6 , pp. 605-615
    • Dontu, G.1
  • 20
    • 0142259346 scopus 로고    scopus 로고
    • The role of Notch in tumorigenesis: Oncogene or tumour suppressor
    • F. Radtke, and K. Raj The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat. Rev. Cancer 3 2003 756 767 (Pubitemid 37328814)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 756-767
    • Radtke, F.1    Raj, K.2
  • 21
    • 65349121368 scopus 로고    scopus 로고
    • Notch signalling in cancer stem cells
    • V. Bolos Notch signalling in cancer stem cells Clin. Transl. Oncol. 11 2009 11 19
    • (2009) Clin. Transl. Oncol. , vol.11 , pp. 11-19
    • Bolos, V.1
  • 22
    • 33644992868 scopus 로고    scopus 로고
    • Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals
    • G. McKenzie Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals BMC Cell Biol. 7 2006 10
    • (2006) BMC Cell Biol. , vol.7 , pp. 10
    • McKenzie, G.1
  • 23
    • 58349091690 scopus 로고    scopus 로고
    • Gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
    • R.D. Meng gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity Cancer Res. 69 2009 573 582
    • (2009) Cancer Res. , vol.69 , pp. 573-582
    • Meng, R.D.1
  • 24
    • 64549091858 scopus 로고    scopus 로고
    • Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism
    • C. Giovannini Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism J. Hepatol. 50 2009 969 979
    • (2009) J. Hepatol. , vol.50 , pp. 969-979
    • Giovannini, C.1
  • 25
    • 43049144313 scopus 로고    scopus 로고
    • Wnt signaling and stem cell control
    • DOI 10.1038/cr.2008.47, PII CR200847
    • R. Nusse Wnt signaling and stem cell control Cell Res. 18 2008 523 527 (Pubitemid 351630946)
    • (2008) Cell Research , vol.18 , Issue.5 , pp. 523-527
    • Nusse, R.1
  • 27
    • 0242551656 scopus 로고    scopus 로고
    • Activation of the Wnt pathway in non small cell lung cancer: Evidence of dishevelled overexpression
    • DOI 10.1038/sj.onc.1206817
    • K. Uematsu Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression Oncogene 22 2003 7218 7221 (Pubitemid 37378553)
    • (2003) Oncogene , vol.22 , Issue.46 , pp. 7218-7221
    • Uematsu, K.1    He, B.2    You, L.3    Xu, Z.4    McCormick, F.5    Jablons, D.M.6
  • 28
    • 85047699343 scopus 로고    scopus 로고
    • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA
    • DOI 10.1038/sj/onc/1205138
    • J. Shou Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA Oncogene 21 2002 878 889 (Pubitemid 34146301)
    • (2002) Oncogene , vol.21 , Issue.6 , pp. 878-889
    • Shou, J.1    Ali-Osman, F.2    Multani, A.S.3    Pathak, S.4    Fedi, P.5    Srivenugopal, K.S.6
  • 29
    • 10144237223 scopus 로고    scopus 로고
    • Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells
    • DOI 10.1002/pros.20117
    • T. Ohigashi Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells Prostate 62 2005 61 68 (Pubitemid 39614295)
    • (2005) Prostate , vol.62 , Issue.1 , pp. 61-68
    • Ohigashi, T.1    Mizuno, R.2    Nakashima, J.3    Marumo, K.4    Murai, M.5
  • 30
    • 57049089995 scopus 로고    scopus 로고
    • Hedgehog signaling in development and cancer
    • J. Jiang, and C.C. Hui Hedgehog signaling in development and cancer Dev. Cell 15 2008 801 812
    • (2008) Dev. Cell , vol.15 , pp. 801-812
    • Jiang, J.1    Hui, C.C.2
  • 31
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • S. Liu Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells Cancer Res. 66 2006 6063 6071
    • (2006) Cancer Res. , vol.66 , pp. 6063-6071
    • Liu, S.1
  • 32
    • 73649145223 scopus 로고    scopus 로고
    • Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion
    • F. Varnat Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion EMBO Mol. Med. 1 2009 338 351
    • (2009) EMBO Mol. Med. , vol.1 , pp. 338-351
    • Varnat, F.1
  • 33
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity
    • DOI 10.1016/j.cub.2006.11.033, PII S0960982206025140
    • V. Clement HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity Curr. Biol. 17 2007 165 172 (Pubitemid 46107823)
    • (2007) Current Biology , vol.17 , Issue.2 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    De Tribolet, N.3    Radovanovic, I.4    Ruiz, I.5    Altaba, A.6
  • 35
    • 70350001754 scopus 로고    scopus 로고
    • Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy
    • N.M. Alajez Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy Cell Death Differ. 16 2009 1469 1479
    • (2009) Cell Death Differ. , vol.16 , pp. 1469-1479
    • Alajez, N.M.1
  • 36
    • 79951980129 scopus 로고    scopus 로고
    • BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer
    • F. Crea BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer Int. J. Cancer 128 2010 1946 1954
    • (2010) Int. J. Cancer , vol.128 , pp. 1946-1954
    • Crea, F.1
  • 37
    • 37249044166 scopus 로고    scopus 로고
    • Comment on tumor growth need not be driven by rare cancer stem cells
    • author reply 1722
    • J.A. Kennedy Comment on "Tumor growth need not be driven by rare cancer stem cells" Science 318 2007 1722 author reply 1722
    • (2007) Science , vol.318 , pp. 1722
    • Kennedy, J.A.1
  • 38
    • 48649104080 scopus 로고    scopus 로고
    • Temozolomide preferentially depletes cancer stem cells in glioblastoma
    • D. Beier Temozolomide preferentially depletes cancer stem cells in glioblastoma Cancer Res. 68 2008 5706 5715
    • (2008) Cancer Res. , vol.68 , pp. 5706-5715
    • Beier, D.1
  • 39
    • 75449109041 scopus 로고    scopus 로고
    • Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients
    • R. Artells Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients Eur. J. Cancer 46 2010 642 649
    • (2010) Eur. J. Cancer , vol.46 , pp. 642-649
    • Artells, R.1
  • 40
    • 58149340463 scopus 로고    scopus 로고
    • Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme
    • R. Pallini Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme Clin. Cancer Res. 14 2008 8205 8212
    • (2008) Clin. Cancer Res. , vol.14 , pp. 8205-8212
    • Pallini, R.1
  • 41
    • 70350746167 scopus 로고    scopus 로고
    • CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer
    • H. Okayama CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer Oncol. Rep. 22 2009 745 755
    • (2009) Oncol. Rep. , vol.22 , pp. 745-755
    • Okayama, H.1
  • 42
    • 70649111149 scopus 로고    scopus 로고
    • Predicting invasive phenotype with CDH1, CDH13, CD44, and TIMP3 gene expression in primary breast cancer
    • A. Celebiler Cavusoglu Predicting invasive phenotype with CDH1, CDH13, CD44, and TIMP3 gene expression in primary breast cancer Cancer Sci. 100 2009 2341 2345
    • (2009) Cancer Sci. , vol.100 , pp. 2341-2345
    • Celebiler Cavusoglu, A.1
  • 43
    • 42649085349 scopus 로고    scopus 로고
    • Prognostic versus predictive value of biomarkers in oncology
    • C.N. Oldenhuis Prognostic versus predictive value of biomarkers in oncology Eur. J. Cancer 44 2008 946 953
    • (2008) Eur. J. Cancer , vol.44 , pp. 946-953
    • Oldenhuis, C.N.1
  • 44
    • 77649272778 scopus 로고    scopus 로고
    • CD133 expression predicts for non-response to chemotherapy in colorectal cancer
    • C.W. Ong CD133 expression predicts for non-response to chemotherapy in colorectal cancer Mod. Pathol. 23 2010 450 457
    • (2010) Mod. Pathol. , vol.23 , pp. 450-457
    • Ong, C.W.1
  • 45
    • 46449115281 scopus 로고    scopus 로고
    • Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
    • A. Murat Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma J. Clin. Oncol. 26 2008 3015 3024
    • (2008) J. Clin. Oncol. , vol.26 , pp. 3015-3024
    • Murat, A.1
  • 46
    • 59649121301 scopus 로고    scopus 로고
    • Co-expression of Bmi-1 and podoplanin predicts overall survival in patients with squamous cell carcinoma of the head and neck treated with radio(chemo)therapy
    • L. Vormittag Co-expression of Bmi-1 and podoplanin predicts overall survival in patients with squamous cell carcinoma of the head and neck treated with radio(chemo)therapy Int. J. Radiat. Oncol. Biol. Phys. 73 2009 913 918
    • (2009) Int. J. Radiat. Oncol. Biol. Phys. , vol.73 , pp. 913-918
    • Vormittag, L.1
  • 47
    • 49649083394 scopus 로고    scopus 로고
    • Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: A tissue microarray study
    • K. Vrzalikova Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study J. Cancer Res. Clin. Oncol. 134 2008 1037 1042
    • (2008) J. Cancer Res. Clin. Oncol. , vol.134 , pp. 1037-1042
    • Vrzalikova, K.1
  • 48
    • 70350383057 scopus 로고    scopus 로고
    • Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer
    • H. Yasuda Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer Oncol. Rep. 22 2009 709 717
    • (2009) Oncol. Rep. , vol.22 , pp. 709-717
    • Yasuda, H.1
  • 49
    • 40849114332 scopus 로고    scopus 로고
    • Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy
    • K.L. Schaefer Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy Eur. J. Cancer 44 2008 699 709
    • (2008) Eur. J. Cancer , vol.44 , pp. 699-709
    • Schaefer, K.L.1
  • 51
    • 74049105514 scopus 로고    scopus 로고
    • CD133 is indicative for a resistance phenotype but does not represent a prognostic marker for survival of non-small cell lung cancer patients
    • A.V. Salnikov CD133 is indicative for a resistance phenotype but does not represent a prognostic marker for survival of non-small cell lung cancer patients Int. J. Cancer 126 2010 950 958
    • (2010) Int. J. Cancer , vol.126 , pp. 950-958
    • Salnikov, A.V.1
  • 53
    • 75349105363 scopus 로고    scopus 로고
    • NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
    • X. Fan NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts Stem Cells 28 2010 5 16
    • (2010) Stem Cells , vol.28 , pp. 5-16
    • Fan, X.1
  • 54
    • 74049145806 scopus 로고    scopus 로고
    • Therapeutic targeting of NOTCH1 signaling in T-cell acute lymphoblastic leukemia
    • T. Palomero, and A. Ferrando Therapeutic targeting of NOTCH1 signaling in T-cell acute lymphoblastic leukemia Clin Lymphoma Myeloma 9 Suppl 3 2009 S205 210
    • (2009) Clin Lymphoma Myeloma , vol.9 , Issue.SUPPL 3 , pp. 205-210
    • Palomero, T.1    Ferrando, A.2
  • 55
    • 76049110053 scopus 로고    scopus 로고
    • Alterations of the Notch pathway in lung cancer
    • B. Westhoff Alterations of the Notch pathway in lung cancer Proc. Natl. Acad. Sci. U.S.A. 106 2009 22293 22298
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 22293-22298
    • Westhoff, B.1
  • 56
    • 33745685874 scopus 로고    scopus 로고
    • Notch3 gene amplification in ovarian cancer
    • J.T. Park Notch3 gene amplification in ovarian cancer Cancer Res. 66 2006 6312 6318
    • (2006) Cancer Res. , vol.66 , pp. 6312-6318
    • Park, J.T.1
  • 57
    • 37549059579 scopus 로고    scopus 로고
    • Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias
    • S.H. Lee Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias APMIS 115 2007 1357 1363
    • (2007) APMIS , vol.115 , pp. 1357-1363
    • Lee, S.H.1
  • 58
    • 77952316663 scopus 로고    scopus 로고
    • NOTCH2 in breast cancer: Association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
    • Y.P. Fu NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations Mol Cancer 9 2010 113
    • (2010) Mol Cancer , vol.9 , pp. 113
    • Fu, Y.P.1
  • 59
    • 75149153252 scopus 로고    scopus 로고
    • HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions
    • M.A. Villaronga HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions Oncogene 29 2010 411 420
    • (2010) Oncogene , vol.29 , pp. 411-420
    • Villaronga, M.A.1
  • 60
    • 45549104579 scopus 로고    scopus 로고
    • Invincible, but not invisible: Imaging approaches toward in vivo detection of cancer stem cells
    • L.S. Hart, and W.S. El-Deiry Invincible, but not invisible: imaging approaches toward in vivo detection of cancer stem cells J. Clin. Oncol. 26 2008 2901 2910
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2901-2910
    • Hart, L.S.1    El-Deiry, W.S.2
  • 62
    • 51649120140 scopus 로고    scopus 로고
    • Review: Biological relevance of disseminated tumor cells in cancer patients
    • S. Riethdorf Review: Biological relevance of disseminated tumor cells in cancer patients Int. J. Cancer 123 2008 1991 2006
    • (2008) Int. J. Cancer , vol.123 , pp. 1991-2006
    • Riethdorf, S.1
  • 63
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • DOI 10.1158/1078-0432.CCR-06-0169
    • M. Balic Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype Clin. Cancer Res. 12 2006 5615 5621 (Pubitemid 44629587)
    • (2006) Clinical Cancer Research , vol.12 , Issue.19 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6    Datar, R.H.7    Cote, R.J.8
  • 64
    • 73649125337 scopus 로고    scopus 로고
    • Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer
    • P.A. Theodoropoulos Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer Cancer Lett. 288 2009 99 106
    • (2009) Cancer Lett. , vol.288 , pp. 99-106
    • Theodoropoulos, P.A.1
  • 65
    • 35848944658 scopus 로고    scopus 로고
    • Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: Research tool or clinical application?
    • DOI 10.1586/14737140.7.10.1463
    • J.E. Lang Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: research tool or clinical application? Expert Rev. Anticancer Ther. 7 2007 1463 1472 (Pubitemid 351826911)
    • (2007) Expert Review of Anticancer Therapy , vol.7 , Issue.10 , pp. 1463-1472
    • Lang, J.E.1    Hall, C.S.2    Singh, B.3    Lucci, A.4
  • 66
    • 33845914033 scopus 로고    scopus 로고
    • The clinical significance of disseminated tumor cells in breast cancer
    • DOI 10.1038/ncponc0685, PII NCPONC0685
    • M.J. Slade, and R.C. Coombes The clinical significance of disseminated tumor cells in breast cancer Nat. Clin. Pract. Oncol. 4 2007 30 41 (Pubitemid 46017692)
    • (2007) Nature Clinical Practice Oncology , vol.4 , Issue.1 , pp. 30-41
    • Slade, M.J.1    Combes, R.C.2
  • 67
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • P. Therasse New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J. Natl. Cancer Inst. 92 2000 205 216
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 205-216
    • Therasse, P.1
  • 68
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • J.M. Llovet Sorafenib in advanced hepatocellular carcinoma N. Engl. J. Med. 359 2008 378 390
    • (2008) N. Engl. J. Med. , vol.359 , pp. 378-390
    • Llovet, J.M.1
  • 69
    • 39449090031 scopus 로고    scopus 로고
    • - prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis
    • DOI 10.1038/sj.bjc.6604242, PII 6604242
    • E.M. Hurt CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis Br. J. Cancer 98 2008 756 765 (Pubitemid 351272625)
    • (2008) British Journal of Cancer , vol.98 , Issue.4 , pp. 756-765
    • Hurt, E.M.1    Kawasaki, B.T.2    Klarmann, G.J.3    Thomas, S.B.4    Farrar, W.L.5
  • 70
    • 54949101585 scopus 로고    scopus 로고
    • Cytokines and their relationship to the symptoms and outcome of cancer
    • B. Seruga Cytokines and their relationship to the symptoms and outcome of cancer Nat. Rev. Cancer 8 2008 887 899
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 887-899
    • Seruga, B.1
  • 74
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • H.S. Robins Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells Blood 114 2009 4099 4107
    • (2009) Blood , vol.114 , pp. 4099-4107
    • Robins, H.S.1
  • 75
    • 55749106963 scopus 로고    scopus 로고
    • Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
    • M.J. Grimshaw Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells Breast Cancer Res. 10 2008 R52
    • (2008) Breast Cancer Res. , vol.10 , pp. 52
    • Grimshaw, M.J.1
  • 76
    • 80055109560 scopus 로고    scopus 로고
    • Isolation, enrichment, and maintenance of medulloblastoma stem cells
    • 10.3791/2086
    • X. Huang Isolation, enrichment, and maintenance of medulloblastoma stem cells J. Vis. Exp. 2010 10.3791/2086
    • (2010) J. Vis. Exp.
    • Huang, X.1
  • 77
    • 77952538478 scopus 로고    scopus 로고
    • Genomic profiling of tumor initiating prostatospheres
    • M.A. Duhagon Genomic profiling of tumor initiating prostatospheres BMC Genomics 11 2010 324
    • (2010) BMC Genomics , vol.11 , pp. 324
    • Duhagon, M.A.1
  • 78
    • 77949889989 scopus 로고    scopus 로고
    • Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo
    • I.P. Garraway Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo Prostate 70 2010 491 501
    • (2010) Prostate , vol.70 , pp. 491-501
    • Garraway, I.P.1
  • 79
    • 58549108859 scopus 로고    scopus 로고
    • The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
    • A. Dubrovska The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations Proc. Natl. Acad. Sci. U.S.A. 106 2009 268 273
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 268-273
    • Dubrovska, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.