The CSN1S1 N and F alleles identified by PCR-SSCP and their associations with milk yield and composition in Chinese dairy goats

Molecular Biology Reports

Volumn 38, Issue 4, 2011, Pages 2821-2825

  Yue, X P ^a   Zhang, X M ^a   Wang, W ^a   Ma, R N ^a   Deng, C J ^a   Lan, X Y ^a   Chen, H ^a,b   Li, F ^a   Xu, X R ^a   Ma, Y ^a   Lei, C Z ^a  

^a NORTHWEST A F UNIVERSITY   (China)

^b JIANGSU NORMAL UNIVERSITY   (China)

Author keywords

CSN1S1; Dairy goat; Milk composition; Milk yield; Polymorphism

Indexed keywords

ALLELE; ARTICLE; BREEDING; CHINA; CONTROLLED STUDY; CSN1S1 F GENE; CSN1S1 N GENE; DNA SEQUENCE; EXON; GENE; GENE DELETION; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GOAT; INTRON; LACTATION; MILK PRODUCTION; NONHUMAN; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; ANIMAL; CHEMISTRY; DAIRYING; GENETICS; METABOLISM; MILK; STATISTICAL MODEL;

CAPRA HIRCUS;

CASEIN; ISOPROTEIN; PRIMER DNA;

ANIMALS; CASEINS; CHINA; DAIRYING; DNA PRIMERS; GOATS; LINEAR MODELS; MILK; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTEIN ISOFORMS;

EID: 79960959985     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0428-0     Document Type: Article

References (23)

1. Barbieri E, Manfredi E, Elsen JM, Ricordeau G, Bouillon J, Grosclaude F, Mahé MF, Bibé B (1995) Effects of the aS1-casein locus on dairy performances and genetic parameters of Alpine goats. Genet Sel Evol 27:437-450
2. Bevilacqua C, Ferranti P, Garro G, Veltri C, Lagonigro R, Leroux C, Pietrolá E, Pilla F, Chianese L, Martin P (2002) Interallelic recombination is probably responsible for the occurrence of a new alpha (s1)-casein variant found in the goat species. Eur J Biochem 269:1293-1303
3. Caroli A, Chiatti F, Chessa S, Rignanese D, Ibeagha-Awemu EM, Erhardt G (2006) Characterization of casein gene complex in west African goats and description of a new aS1-casein polymorphism. J Dairy Sci 90:2989-2996
4. Chianese L, Ferranti P, Garro G, Mauriello R, Addeo F (1997) Occurrence of three novel aS1-casein variants in goat milk. IDFFIL seminar on milk protein polymorphism, Palmerston North pp. 259-267
5. Chilliard Y, Ferlay A (2004) Dietary lipids and forages interactions on cow and goat milk fatty acid composition and sensory properties. Reprod Nutr Dev 44:467-492
6. Clark S, Sherbon JW (2000) Genetic variants of alphas1-CN in goat milk: breed distribution and associations with milk composition and coagulation properties. Small Rumin Res 38:135-143
7. Cosenza G, Illario R, Rando A, Di Gregorio P, Masina P, Ramunno L (2003) Molecular characterization of the goat CSN1S1 01 allele. J Dairy Res 70:237-240
8. Cosenza G, Pauciullo A, Gallo D, Colimoro L, D'Avino A, Mancusi A, Ramunno L (2008) Genotyping at the CSN1S1 locus by PCR-RFLP and AS-PCR in a Neapolitan goat population. Small Rumin Res 74:84-90
9. Ferretti L, Leone P, Sgaramella V (1990) Long range restriction analysis of the bovine casein genes. Nucl Acids Res 18: 6829-6833
10. Grosclaude F, Mahé MF, Brignon G, di Stasio L, Juenet R (1987) A Mendelian polymorphism underlying quantitative variation of goat aS1-casein. Genet Sel Evol 19:399-412
11. Lan XY, Pan CY, Chen H, Zhang CL, Li JY, Zhao M, Lei CZ, Zhang AL, Zhang L (2007) An AluI PCR-RFLP detecting a silent allele at the goat POU1F1 locus and its association with production traits. Small Rumin Res 73:8-12
12. Leroux C, Mazure N, Martin P (1992) Mutations away from splice site recognition sequences might cis-modulate alternative splicing of goat aS1-casein transcripts, structural organization of the relevant gene. J Biol Chem 267:6147-6157
13. MahéMF, Manferedi E, Ricordeau G, Piacere A, Grosclaude F (1994) Effets du polymorphisme de la caséine as1 caprine sur les performances laitiéres: analyse intradescendance de boucs de race Alpine. Genet Sel Evol 26:151-157
14. Manfredi E, Barbieri ME, Bouillon J, Piacere A, MahéMF, Grosclaude E, Ricordeau G (1993) Effects of alpha (S1) casein variants on dairy performance in goats. Lait 73:567-572
15. Martin P, Ollivier-Bousquet M, Grosclaude F (1999) Genetic polymorphism of casein: a tool to investigate casein micelle organization. Int Dairy J 9:163-171
16. Ramunno L, Rando A, Di Gregorio P, Massari M, Blassi M, Masina P (1991) Structura genetica di alcune popuoazioni caprine allevate in Italian a locus della caseina-aS1. In: Proc. IX Congr. NazASPA, Milan, p 579
17. Ramunno L, Cosenza G, Rando A, Pauciullo A, Illario R, Gallo D, DiBerardino D, Masina P (2005) Comparative analysis of gene sequence of goat CSN1S1 F and N alleles and characterization of CSN1S1 transcript variants in mammary gland. Gene 345:289-299
18. Ramunno L, Cosenza G, Pappalardo M, Pastore N, Gallo D, Di Gregorio P, Masina P (2000) Identification of the goat CSN1S1 F allele by means of PCR-RFLP method. Anim Genet 31:342-343
19. Remeuf F (1993) Influence of genetic-polymorphism of caprine alpha (S1)-casein on physiochemical and technological properties of goats milk. Lait 73:549-557
20. Threadgill DW, Womack JE (1990) Genomic analysis of the major bovine 17 milk proteins genes. Nucl Acids Res 18:6935-6942
21. Lan X, Pan C, Zhang L, Zhao M, Zhang C, Lei C, Chen H (2009) A novel missense (A79 V) mutation of goat PROP1 gene and its association with production traits. Mol Biol Rep 36(8):2069-2073
22. Lan X, Lai X, Li Z, Wang J, Lei C, Chen H (2010) Effects of genetic variability of the carpine homeobox transcription factor HESX1 gene on performance traits. Mol Biol Rep 37(1):441-449
23. Li Z, Chen Z, Lan X, Ma L, Qu Y, Liu Y, Li M, Wang P, Li F, Chen H (2010) Two novel cSNPs of weaver gene in Chinese indigenous goat and their associations with milk yield. Mol Biol Rep 37(1):563-569