Recommendations on clinical proof of efficacy for potential scar prevention and reduction therapies

Wound Repair and Regeneration

Volumn 19, Issue SUPPL. 1, 2011, Pages s32-s37

  Bush, James A ^a   McGrouther, D Angus ^b   Young, V Leroy ^c   Herndon, David N ^d   Longaker, Michael T ^e   Mustoe, Thomas A ^f   Ferguson, Mark W J ^a,b  

^a Renovo Group Plc   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c BodyAesthetic Plastic Surgery and Skincare Center   (United States)

^d SHRINERS HOSPITALS FOR CHILDREN   (United States)

^e STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^f NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE DISTRIBUTION; ANESTHESIST; ARTICLE; CLINICAL ASSESSMENT TOOL; CUSHING SYNDROME; DIABETES MELLITUS; GOLD STANDARD; HUMAN; MECHANICS; MEDICAL RESEARCH; MORPHOLOGY; NUTRITIONAL DEFICIENCY; OBESITY; PRIORITY JOURNAL; RACE DIFFERENCE; REGENERATIVE MEDICINE; SCAR; SEX DIFFERENCE; SKIN SCAR; SMOKING; SUBJECTIVE ASSESSMENT METHOD; SURGEON; TREATMENT INDICATION; TREATMENT OUTCOME; WOUND CLOSURE; WOUND DRESSING; WOUND HEALING;

EID: 79960948512     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2010.00607.x     Document Type: Article

References (60)

1. Ward CM., Surgical research, experimentation and innovation. Br J Plast Surg 1994; 47: 90-4. (Pubitemid 24076500)
2. Rudicel S, Esdaile J., The randomised clinical trial in orthopaedics: obligation or option? J Bone Joint Surg Am 1985; 67: 1284-93. (Pubitemid 16222977)
3. Jimenez RE, Gutierrez AR, Benitez IM., Methodologic requirements for assessing surgical procedures in current medical literature. World J Surg 2003; 27: 229-33. (Pubitemid 36920175)
4. Rosner F., The ethics of randomised clinical trials. Am J Med 1987; 82: 283-90.
5. Durani P, Bayat A., Levels of evidence for the treatment of keloid disease. J Plast Reconstr Aesthet Surg 2008; 61: 4-17. (Pubitemid 350199116)
6. Lavori PW, Louis TA, Bailar JC, Polansky M., Designs for experiments-parallel comparisons of treatment. N Engl J Med 1983; 309: 1291-9.
7. Bayat A, McGrouther DA, Ferguson MWJ,. Skin scarring. Br Med J 2003; 326: 88-92. (Pubitemid 36092292)
8. Louis TA, Lavori PW, Bailar JC, Polansky M,. Crossover and self-controlled designs in clinical research. N Engl J Med 1984; 310: 24-31. (Pubitemid 14212477)
9. Burd A, Huang L., Hypertrophic response and keloid diathesis: two very different forms of scar. Plast Reconstr Surg 2005; 116: 150e-7e.
10. Bond JS, Duncan JA, Sattar A, Boanas A, Mason T, O'Kane S, Ferguson MW,. Maturation of the human scar: an observational study. Plast Reconstr Surg 2008; 121: 1650-8. (Pubitemid 351642718)
11. Ashcroft GS, Mills SJ, Ashworth JJ., Ageing and wound healing. Biogerontology 2002; 3: 337-45.
12. Ashcroft GS, Horan MA, Herrick SE, Tarnuzzer RW, Schultz GS, Ferguson MW,. Age-related differences in the temporal and spatial regulation of matrix metalloproteinases (MMPs) in normal skin and acute cutaneous wounds of healthy humans. Cell Tissue Res 1997; 290: 581-91. (Pubitemid 27522258)
13. Ashcroft GS, Kielty CM, Horan MA, Ferguson MWJ., Age-related changes in the temporal and spatial distributions of fibrillin and elastin mRNAs and proteins in acute cutaneous wounds of healthy humans. J Path 1997; 183: 80-9. (Pubitemid 27368531)
14. Vitellaro-Zuccarello L, Cappelletti S, Dal Pozzo Rossi V, Sari-Gorla M., Stereological analysis of collagen and elastic fibers in the normal human dermis: variability with age, sex and body region. Anat Rec 1994; 238: 153-62. (Pubitemid 24018179)
15. Gilliver SC, Ashworth JJ, Ashcroft GS., The hormonal regulation of cutaneous wound healing. Clin Dermatol 2007; 25: 56-62. (Pubitemid 46177465)
16. Borges AF., The scar prognosis of wounds. Br J Plast Surg 1960; 13: 47-54.
17. Muir IF., On the nature of keloid and hypertrophic scars. Br J Plast Surg 1990; 43: 61-9.
18. Silverstein P., Smoking and wound healing. Am J Med 1992; 93 (Suppl. 1A): 22S-4S.
19. Arnold M, Barbul A., Nutrition and wound healing. Plast Reconstr Surg 2006; 117 (Suppl.): 42S-58S. (Pubitemid 44317771)
20. Platt AJ, Mohan D, Baguley P., The effect of body mass index and wound irrigation on outcome after bilateral breast reconstruction. Ann Plast Surg 2003; 51: 552-5. (Pubitemid 37499358)
21. Koivukangas V, Annala A-P, Salmela PI, Oikarinen A., Delayed restoration of epidermal barrier function after suction blister injury in patients with diabetes mellitus. Diabetic Med 1999; 16: 563-7.
22. Zervolea I, Pratsinis H, Tsagarakis S, Karavitaki N, Stathakos D, Thalassinos N, Kletsas D., The impact of chronic in vivo glucocorticoid excess on the functional characteristics of human skin fibroblasts obtained from patients with endogenous Cushing's syndrome. Eur J Endocrinol 2005; 152: 895-902. (Pubitemid 40903581)
23. Franz MG, Robson MC, Steed DL, Barbul A, Brem H, Cooper DM, Leaper D, Milner SM, Payne WG, Wachtel TL, Wiersema-Bryant L., Guidelines to aid healing of acute wounds by decreasing impediments of healing. Wound Rep Regen 2008; 16: 723-48.
24. Ketchum LD, Cohen IK, Masters FW., Hypertropic scars and keloids. A collective review. Plast Reconstr Surg 1974; 53: 140-54.
25. Bayat A, Arscott G, Ollier WER, Ferguson MWJ, McGrouther DA., Description of site-specific morphology of keloid phenotypes in an Afro-Caribbean population. Br J Plast Surg 2004; 57: 122-33. (Pubitemid 38239884)
26. Cox HT., The cleavage lines of the skin. Br J Surg 1942; 29: 234-40.
27. Ridge MD, Wright V., The directional effects of skin. A bioengineering study of skin with particular reference to Langer's Lines. J Invest Dermatol 1966; 46: 341-6.
28. Langer K., On the anatomy and physiology of the skin II. Skin tension. Br J Plast Surg 1978; 31: 93-106.
29. Simon HK, Zempsky WT, Bruns TB, Sullivan KM., Lacerations against Langer's lines: to glue or suture? J Emerg Med 1998; 16: 185-9. (Pubitemid 28155431)
30. Meyer M, McGrouther DA., A study relating wound tension to scar morphology in the pre-sternal scar using Langer's technique. Br J Plast Surg 1991; 44: 291-4.
31. Wray RC., Force required for wound closure and scar appearance. Plast Reconstr Surg 1983; 72: 380-2. (Pubitemid 13040074)
32. Arem AJ, Madden JW., Effects of stress on healing wounds. J Surg Res 1976; 20: 93-102.
33. Burgess LPA, Morin GV, Rand M, Vossoughi J, Hollinger JO., Wound healing. Relationship of wound closing tension to scar width in rats. Arch Otolaryngol Head Neck Surg 1990; 116: 798-802. (Pubitemid 20218756)
34. Bernard L, Doyle J, Friedlander SF., A prospective comparison of Octyl Cyanoacrylate tissue adhesive (Dermabond) and suture for the closure of excisional wounds in children and adolescents. Arch Dermatol 2001; 137: 1177-80. (Pubitemid 32847839)
35. Melandri D, De Angelis A, Orioli R, Ponzielli G, Lualdi P, Giarratana N, Reiner V., Use of a new hemicellulose dressing (Veloderm) for the treatment of split-thickness donor sites. A within-patient controlled study. Burns 2006; 32: 964-72. (Pubitemid 44647542)
36. Innes ME, Umraw N, Fish JS, Gomez M, Cartotto RC., The use of silver coated dressings on donor site wounds: a prospective, controlled matched pair study. Burns 2001; 27: 621-7. (Pubitemid 32755754)
37. Grantcharov TP, Bardram L, Funch-Jensen P, Rosenberg J., Learning curves and impact of previous operative experience on performance on a virtual reality simulator to test laparoscopic surgical skills. Am J Surg 2003; 185: 146-9. (Pubitemid 36143904)
38. Monk TH, Buysse DJ, Reynolds CF 3rd, Berga SL, Jarrett DB, Begley AE, Kupfer DJ., Circadian rhythms in human performance and mood under constant conditions. J Sleep Res 1997; 6: 9-18. (Pubitemid 27154249)
39. Reznick RK, Folse JR., Effect of sleep deprivation on the performance of surgical residents. Am J Surg 1987; 154: 520-5. (Pubitemid 18022634)
40. Durani P, McGrouther DA, Ferguson MWJ., Current scales for assessing human scarring: a review. J Plast Reconstr Aesthet Surg 2009; 62: 713-20.
41. Capon A, Iarmarcovai G, Gonnelli D, Degardin N, Magalon G, Mordon S., Scar prevention using laser-assisted skin healing (LASH) in plastic surgery. Aesth Plast Surg 2010; Epub: doi DOI: 10.1007/s00266-009-9469-y.
42. Nouri K, Rivas MP, Stevens M, Ballard CJ, Singer L, Ma F, Vejjabhinanta V, Elsaie ML, Elgart GW., Comparison of the effectiveness of the pulsed dye laser 585 nm versus 595 nm in the treatment of new surgical scars. Lasers Med Sci 2009; 24: 801-10.
43. Ferguson MW, Duncan J, Bond J, Bush J, Durani P, So K, Taylor L, Chantrey J, Mason T, James G, Laverty H, Occleston NL, Sattar A, Ludlow A, O'Kane S., Prophylactic administration of avotermin on skin scarring: three double-blind, placebo-controlled, phase I/II studies. Lancet 2009; 373: 1264-74.
44. Jih MH, Friedman PM, Goldberg LH, Robles M, Glaich AS, Kimyai-Asadi A., The 1450-nm diode laser for facial inflammatory acne vulgaris: dose response and 12-month follow-up study. J Am Acad Dermatol 2006; 55: 80-7. (Pubitemid 43867039)
45. Orringer JS, Kang S, Maier L, Johnson TM, Sachs DL, Karimipour DJ, Helfrich YR, Hamilton T, Voorhees JJ., A randomized, controlled, split-face clinical trial of 1320-nm Nd: YAG laser therapy in the treatment of acne vulgaris. J Am Acad Dermatol 2007; 56: 432-8. (Pubitemid 46273857)
46. Wiegell SR, Wulf HC., Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate. J Am Acad Dermatol 2006; 54: 647-51.
47. Butler EG, McClellan SD, Ross EV., Split treatment of photodamaged skin with KTP 532 nm laser with 10 mm handpiece versus IPL: a cheek-to-cheek comparison. Lasers Surg Med 2006; 38: 124-8.
48. Medicis Aesthetics Holdings Inc. FDA document. Summary of safety and effectiveness for FDA approved product: Restylane, P040024. Medicis Aesthetics Holdings Inc., US Food and Drug Administration: Silver Spring, MD; 2005.
49. Inamed Corporation. FDA document. Summary of safety and effectiveness for FDA approved product: Juvederm, P050047. Inamed Corporation, US Food and Drug Administration: Silver Spring, MD; 2006.
50. BioForm Medical Inc. FDA document. Summary of safety and effectiveness for FDA approved product: Radiesse, P050052. BioForm Medical Inc., US Food and Drug Administration: Silver Spring, MD; 2006.
51. Anika Therapeutics Inc. FDA document. Summary of safety and effectiveness for FDA approved product: Cosmetic Tissue Augmentation product, P050033. Anika Therapeutics Inc., US Food and Drug Administration: Silver Spring, MD; 2006.
52. Early treatment diabetic retinopathy study design and baseline patient characteristics. ETDRS report number 7. Ophthalmology 1991; 98: 741-756.
53. Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early treatment diabetic retinopathy study research group. Ophthalmology 1991; 98 (Suppl.): 766-785.
54. Antczak-Bouckoms AA, Tulloch JFK, Berkey CS., Split-mouth and cross-over designs in dental research. J Clin Periodontol 1990; 17: 446-53. (Pubitemid 20231070)
55. de Assis Cde A, Antoniazzi RP, Zanatta FB, Rösing CK., Efficacy of Gluma desensitizer on dentin hypersensitivity in periodontally treated patients. Braz Oral Res 2006; 20: 252-6. (Pubitemid 44613642)
56. Graziani F, D'Aiuto F, Arduino PG, Tonelli M, Gabriele M., Perioperative dexamethasone reduces post-surgical sequelae of wisdom tooth removal. A split-mouth randomized double-masked clinical trial. Int J Oral Maxillofac Surg 2006; 35: 241-6. (Pubitemid 43154392)
57. Li-Tsang CW, Lau JC, Choi J, Chan CC, Jinan L., A prospective randomized clinical trial to investigate the effect of silicone gel sheeting (Cica-Care) on post-traumatic hypertrophic scar among the Chinese population. Burns 2006; 32: 678-83. (Pubitemid 44293058)
58. De Giogi V, Sestini S, Mannone F, Papi F, Alfaioli B, Gori A, Lotti T., The use of silicone gel in the treatment of fresh surgical scars: a randomised study. Clin Exp Dermatol 2009; 34: 688-93.
59. Ono I, Akasaka Y, Kikuchi R, Sakemoto A, Kamiya T, Yamashita T, Jimbow K., Basic fibroblast growth factor reduces scar formation in acute incisional wounds. Wound Rep Regen 2007; 15: 617-23. (Pubitemid 47493894)
60. Burd A., So what is a keloid scar? J Plast Reconstr Aesthet Surg 2008; 61: 1-3. (Pubitemid 350199126)