Coagulant effects of black snake (Pseudechis spp.) venoms and in vitro efficacy of commercial antivenom

Toxicon

Volumn 58, Issue 3, 2011, Pages 239-246

  Lane, J ^a,b   O'Leary, M A ^c   Isbister, G K ^b,c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

Author keywords

Anticoagulation; Coagulopathy; Phospholipase A2; Pseudechis; Venom

Indexed keywords

4 BROMOPHENACYL BROMIDE; IMMUNOGLOBULIN G; PHOSPHOLIPASE A2; SNAKE VENOM; SNAKE VENOM ANTISERUM;

ANTIBODY SPECIFICITY; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING DISORDER; CONTROLLED STUDY; CROSS REACTION; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NOTECHIS; NOTECHIS SCUTATUS; PRIORITY JOURNAL; PSEUDECHIS; PSEUDECHIS AUSTRALIS; PSEUDECHIS PORPHYRIACUS; SERODIAGNOSIS; SNAKE; TURBIDIMETRY;

ACETOPHENONES; ANIMALS; ANTIVENINS; BLOOD COAGULATION; CROSS REACTIONS; ELAPID VENOMS; HUMANS; PHOSPHOLIPASES A2; RABBITS;

NOTECHIS SCUTATUS; ORYCTOLAGUS CUNICULUS; PSEUDECHIS; PSEUDECHIS AUSTRALIS; PSEUDECHIS PORPHYRIACUS; SERPENTES; SPILOTES PULLATUS PULLATUS;

EID: 79960945923     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2011.05.020     Document Type: Article

References (33)

1. Campbell C.H. Myotoxic paralysis and hemolytic anemia due to king brown snake bite. Australian & New Zealand Journal of Medicine 1984, 14(2):169.
2. Chester A., Crawford G.P. In vitro coagulant properties of venoms from Australian snakes. Toxicon 1982, 20(2):501-504.
3. Churchman A., O'Leary M., et al. Clinical effects of red-bellied black snake (Pseudechis porphyriacus) envenoming and correlation with venom concentrations: Australian snakebite project (ASP-11). Medical Journal of Australia 2010, 193(11/12):696-700.
4. Cogger H. Reptiles and Amphibians of Australia 2000, Reed Books Australia, Port Melbourne.
5. Currie B.J. Snakebite in tropical Australia: a prospective study in the "top end" of the Northern Territory. Medical Journal of Australia 2004, 181(11-12):693-697.
6. Dambisya Y.M., Lee T.-L., et al. Action of Calloselasma rhodostoma (Malayan pit viper) venom on human blood coagulation and fibrinolysis using computerized thromboelastography (CTEG). Toxicon 1994, 32(12):1619.
7. Isbister G.K. Snake bite: a current approach to management. Australian Prescriber 2006, 29(5):125-129.
8. Isbister G.K. Procoagulant snake toxins: laboratory studies, diagnosis, and understanding snakebite coagulopathy. Seminars in Thrombosis & Hemostasis 2009, 35(1):93-103.
9. Isbister G.K., Hooper M.R., et al. Collett's snake (Pseudechis colletti) envenoming in snake handlers. Qjm 2006, 99(2):109-115.
10. Isbister G.K., O'Leary M.A., et al. Cross-neutralisation of Australian brown snake, Taipan and death adder venoms by monovalent antibodies. Vaccine 2010, 28(3):798-802.
11. Isbister G.K., Scorgie F.E., et al. Factor deficiencies in venom induced consumption coagulopathy resulting from Australian elapid envenomation: Australian snakebite project (ASP-10). Journal of Thrombosis & Haemostasis 2010, 8(11):2504-2513.
12. Jansen M., McLeod M., et al. Spotted black snake (Pseudechis guttatus) envenoming. Medical Journal of Australia 2007, 186(1):41-42.
13. Kamiguti A.S., Laing G.D., et al. Biological properties of the venom of the Papuan black snake (Pseudechis papuanus): presence of a phospholipase A2 platelet inhibitor. Toxicon 1994, 32(8):915-925.
14. Kini R.M. Anticoagulant proteins from snake venoms: structure, function and mechanism. Biochemical Journal 2006, 397(3):377-387.
15. Laing G.D., Kamiguti A.S., et al. Characterisation of a purified phospholipase A2 from the venom of the Papuan black snake (Pseudechis papuanus). Biochimica et Biophysica Acta 1995, 1250(2):137-143.
16. Lalloo D., Trevett A., et al. Neurotoxicity and haemostatic disturbances in patients envenomed by the Papuan black snake (Pseudechis papuanus). Toxicon 1994, 32(8):927-936.
17. Lomonte B., Angulo Y., et al. An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action. Toxicon 2003, 42:901-995.
18. Madaras F., Smith I., et al. Purification and characterisation of coagulation inhibitors from the King Brown venom [abstract]. Clinical & Experimental Pharmacology & Physiology 1983, 10:490.
19. Marshall L.R., Herrmann R.P. Coagulant and anticoagulant actions of Australian snake venoms. Thrombosis & Haemostasis 1983, 50(3):707-711.
20. O'Leary M.A., Isbister G.K. Commercial monovalent antivenoms in Australia are polyvalent. Toxicon 2009, 54(2):192.
21. O'Leary M.A., Isbister G.K. A turbidimetric assay for the measurement of clotting times of procoagulant venoms in plasma. Journal of Pharmacological & Toxicological Methods 2010, 61(1):27-31.
22. O'Leary M.A., Kornhauser R.S., et al. An examination of the activity of expired and mistreated commercial Australian antivenoms. Transactions of the Royal Society of Tropical Medicine and Hygiene 2009, 103(9):937.
23. O'Leary M.A., Schneider J.J., et al. Cross-neutralisation of Australian brown and tiger snake venoms with commercial antivenoms: cross-reactivity or antivenom mixtures?. Toxicon 2007, 50(2):206.
24. Pearn J., McGuire B., et al. The envenomation syndrome caused by the Australian red-bellied Black Snake Pseudechis porphyriacus. Toxicon 2000, 38(12):1715-1729.
25. Ramasamy S., Isbister G.K., et al. The efficacy of two antivenoms against the in vitro myotoxic effects of black snake (Pseudechis) venoms in the chick biventer cervicis nerve-muscle preparation. Toxicon 2004, 44(8):837-845.
26. St Pierre L., Masci P., et al. Comparative analysis of prothrombin activators from the venom of Australian elapids. Molecular Biology and Evolution 2005, 22:1853-1864.
27. Tan N.-H., Ponnudurai G. A comparative study of the biological properties of Australian elapid venoms. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 1990, 97(1):99.
28. Vines A. Severe local reaction to bite of King Brown snake. Medical Journal of Australia 1978, 1(12):657.
29. Volwerk J., Pieterson W., et al. Histidine at the active site of phospholipase A2. Biochemistry 1974, 13(7):1446-1454.
30. Wagstaff S., Laing G., et al. Bioinformatics and multiepitope DNA immunization to design rational snake antivenom. PLoS Medicine 2006, 3:e184.
31. Wagstaff S., Sanz L., et al. Combined snake venomics and venom gland transcriptomic analysis of the ocellated carpet Viper, Echis ocellatus. Journal of Proteomics 2009, 71:609-623.
32. White J. "Envenoming and antivenom use in Australia. Toxicon 1998, 36(11):1483.
33. White J. CSL Antivenom Handbook 2001, CSL Ltd, Melbourne.