Cross-neutralisation of Australian brown snake, taipan and death adder venoms by monovalent antibodies

Vaccine

Volumn 28, Issue 3, 2010, Pages 798-802

  Isbister, Geoffrey K ^a,b,c   O'Leary, Margaret A ^a   Hagan, Jessica ^b   Nichols, Kearney ^b   Jacoby, Tammy ^d   Davern, Kathleen ^d   Hodgson, Wayne C ^e   Schneider, Jennifer J ^b  

^a CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

Antivenom; Cross neutralisation; Snake venom

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; SNAKE VENOM; SNAKE VENOM ANTISERUM;

ACANTHOPHIS ANTARCTICUS; ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DRUG MECHANISM; ENZYME IMMUNOASSAY; MALE; NEUROTOXICITY; NONHUMAN; OXYURANUS SCUTELLATUS; PRIORITY JOURNAL; PSEUDONAJA TEXTILIS; SNAKE;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIVENINS; AUSTRALIA; BLOOD COAGULATION; CROSS REACTIONS; ELAPIDAE; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN G; NEURONS; RABBITS; VENOMS;

EID: 71149107454     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.10.055     Document Type: Article

References (17)

1. Theakston R.D.G., and Warrell D.A. Crisis in snake antivenom supply for Africa. Lancet 356 (2000) 2104
2. O'Leary M.A., Schneider J.J., Krishnan B.P., Lavis C., McKendry A., Ong L.K., et al. Cross-neutralisation of Australian brown and tiger snake venoms with commercial antivenoms: cross-reactivity or antivenom mixtures?. Toxicon 50 (2007) 206-213
3. Isbister G.K. Procoagulant snake toxins: laboratory studies, diagnosis, and understanding snakebite coagulopathy. Semin Thromb Hemost 35 (2009) 93-103
4. Kuruppu S., Smith A.I., Isbister G.K., and Hodgson W.C. Neurotoxins from Australo-Papuan elapids: a biochemical and pharmacological perspective. Crit Rev Toxicol 38 (2008) 73-86
5. St Pierre L., Masci P.P., Filippovich I., Sorokina N., Marsh N., Miller D.J., et al. Comparative analysis of prothrombin activators from the venom of Australian elapids. Mol Biol Evol 22 (2005) 1853-1864
6. Pearson J.A., Tyler M.I., and Howden M.E. Immunological relationships between the subunits of textilotoxin and rabbit antisera raised against textilotoxin and some snake venoms. Toxicon 29 (1991) 375-378
7. Wickramaratna J.C., and Hodgson W.C. A pharmacological examination of venoms from three species of death adder (Acanthophis antarcticus, Acanthophis praelongus and Acanthophis pyrrhus). Toxicon 39 (2001) 209-216
8. O'Leary MA, Isbister GK. A turbidimetric assay for the measurement of clotting times of procoagulant venoms in plasma. J Pharmacol Toxicol Methods 2009 Jul 14. [Epub ahead of print] doi:10.1016/j.vascn.2009.06.004.
9. O'Leary M.A., Isbister G.K., Schneider J.J., Brown S.G., and Currie B.J. Enzyme immunoassays in brown snake (Pseudonaja spp.) envenoming: detecting venom, antivenom and venom-antivenom complexes. Toxicon 48 (2006) 4-11
10. Isbister G.K., Halkidis L., O'Leary M.A., Whitaker R., Cullen P., Mulcahy R., et al. Human anti-snake venom IgG antibodies in a previously bitten snake-handler, but no protection against local envenoming. Toxicon (2009) Aug 5. [Epub ahead of print]
11. Isbister G.K., Woods D., Alley S., O'Leary M.A., Seldon M., and Lincz L. Endogenous thrombin potential as a novel method for the characterization of procoagulant snake venoms. Haematology Society of Australia and New Zealand Annual Conference. Perth (2008)
12. Currie B.J. Snakebite in tropical Australia: a prospective study in the "Top End" of the Northern Territory. Med J Aust 181 (2004) 693-697
13. Birrell G.W., Earl S., Masci P.P., de Jersey J., Wallis T.P., Gorman J.J., et al. Molecular diversity in venom from the Australian brown snake, Pseudonaja textilis. Mol Cell Proteom (2005)
14. Isbister G.K., O'Leary M.A., Schneider J.J., Brown S.G., and Currie B.J. Efficacy of antivenom against the procoagulant effect of Australian brown snake (Pseudonaja sp.) venom: in vivo and in vitro studies. Toxicon 49 (2007) 57-67
15. Isbister G.K., Duffull S.B., and Brown S.G. Failure of antivenom to improve recovery in Australian snakebite coagulopathy. QJM 102 (2009) 563-568
16. Wagstaff S.C., Sanz L., Juarez P., Harrison R.A., and Calvete J.J. Combined snake venomics and venom gland transcriptomic analysis of the ocellated carpet viper, Echis ocellatus. J Proteom 71 (2009) 609-623
17. Wagstaff S.C., Laing G.D., Theakston R.D., Papaspyridis C., and Harrison R.A. Bioinformatics and multiepitope DNA immunization to design rational snake antivenom. PLoS Med 3 (2006) e184