The effects of short-course preoperative irradiation on local recurrence rate and survival in rectal cancer: A Population-based nationwide study

Diseases of the Colon and Rectum

Volumn 54, Issue 6, 2011, Pages 672-680

  Tiefenthal, Marit ^a   Nilsson, Per J ^b,c   Johansson, Robert ^d   Glimelius, Bengt ^c,e   Pahlman, Lars ^f  

^a ERSTA HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^e UPPSALA UNIVERSITY   (Sweden)

^f Department of Surgical Sciences ^*  (Sweden)

Author keywords

Colon and rectal surgery; Radiation oncology; Rectal cancer

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER REGISTRY; CANCER SIZE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CHEMORADIOTHERAPY; DISEASE FREE SURVIVAL; FEMALE; HARTMANN PROCEDURE; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OVERALL SURVIVAL; POPULATION RESEARCH; PREOPERATIVE PERIOD; PREOPERATIVE RADIOTHERAPY; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM CANCER; RECURRENCE RISK; RETROSPECTIVE STUDY; SHORT COURSE THERAPY; SURVIVAL RATE; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PREOPERATIVE CARE; PROPORTIONAL HAZARDS MODEL; RECTUM TUMOR; REGISTER; RISK FACTOR; SURVIVAL; SWEDEN; TREATMENT OUTCOME; TUMOR RECURRENCE;

AGED; AGED, 80 AND OVER; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PREOPERATIVE CARE; PROPORTIONAL HAZARDS MODELS; RECTAL NEOPLASMS; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL ANALYSIS; SWEDEN; TREATMENT OUTCOME;

EID: 79960940571     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/DCR.0b013e318210c067     Document Type: Article

References (34)

1. Improved survival with preoperative radiotherapy in respectable rectal cancer. Swedish Rectal Cancer Trial. N Engl J Med. 1997; 336:980-987.
2. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for respectable rectal cancer. N Engl J Med. 2001;345:638-646.
3. Glimelius B, Gronberg H, Jarhult J, Wallgren A, Cavallin-Stahl E. A systematic overview of radiation therapy effects in rectal cancer. Acta Oncol. 2003;42:476-492. (Pubitemid 37193839)
4. Heald RJ, Ryall RD. Recurrence and survival after total mesorectal excision for rectal cancer. Lancet. 1986;1:1479-1482. (Pubitemid 16095660)
5. Kapiteijn E, van de Velde CJ. The role of total mesorectal excision in the management of rectal cancer. Surg Clin North Am. 2002;82:995-1007. (Pubitemid 35463080)
6. Smith N, Brown G. Preoperative staging of rectal cancer. Acta Oncol. 2008;47:20-31.
7. Martling A, Cedermark B, Johansson H, Rutqvist LE, Holm T. The surgeon as a prognostic factor after the introduction of total mesorectal excision in the treatment of rectal cancer. Br J Surg. 2002;89:1008-1013. (Pubitemid 34994693)
8. Nagtegaal ID, van Krieken JH. The role of pathologists in the quality control of diagnosis and treatment of rectal cancer-an overview. Eur J Cancer. 2002;38:964-972. (Pubitemid 34442324)
9. Braendengen M, Tveit KM, Berglund A, et al. Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer. J Clin Oncol. 2008;26:3687-3694.
10. Daniels IR, Fisher SE, Heald RJ, Moran BJ. Accurate staging, selective preoperative therapy and optimal surgery improves outcome in rectal cancer: a review of the recent evidence. Colorectal Dis. 2007;9:290-301. (Pubitemid 46563458)
11. Birgisson H, Påhlman L, Gunnarsson U, Glimelius B, Swedish Rectal Cancer Trial Group. Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial. J Clin Oncol. 2005;23:8697-8705. (Pubitemid 46211513)
12. Birgisson H, Påhlman L, Gunnarsson U, Glimelius B. Occurrence of second cancers in patients treated with radiotherapy for rectal cancer. J Clin Oncol. 2005;23:6126-6131.
13. Birgisson H, Påhlman L, Gunnarsson U, Glimelius B. Late adverse effects of radiation therapy for rectal cancer-a systematic overview. Acta Oncol. 2007;46:504-516. (Pubitemid 46752252)
14. Peeters KC, Marijnen CA, Nagtegaal ID, et al. The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma. Ann Surg. 2007;246:693-701. (Pubitemid 350035641)
15. Sebag-Montefiore D, Stephens RJ, Steele R, et al. Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet. 2009;373:811-820.
16. Hermanek P, Heald RJ. Pre-operative radiotherapy for rectal carcinoma? Has the case really been made for short course preoperative radiotherapy if surgical standards for rectal carcinoma are optimal? Colorectal Dis. 2004;6:10-14. (Pubitemid 38195485)
17. Simunovic M, Sexton R, Rempel E, Moran BJ, Heald RJ. Optimal preoperative assessment and surgery for rectal cancer may greatly limit the need for radiotherapy. Br J Surg. 2003;90:999-1003. (Pubitemid 37026331)
18. Påhlman L, Bohe M, Cedermark B, et al. The Swedish rectal cancer registry. Br J Surg. 2007;94:1285-1292. (Pubitemid 47584780)
19. Pettersson D, Cedermark B, Holm T, et al. Interim analysis of the Stockholm III trial of preoperative radiotherapy regimens for rectal cancer. Br J Surg. 2010;97:580-587.
20. Gunnlaugsson A, Anderson H, Fernebro E, et al. Multicentre phase II trial of capecitabine and oxaliplatin in combination with radiotherapy for unresectable colorectal cancer: the CORGI-L Study. Eur J Cancer. 2009;45:807-813.
21. Radu C, Berglund A, Påhlman L, Glimelius B. Short-course preoperative radiotherapy with delayed surgery in rectal cancer-a retrospective study. Radiother Oncol. 2008;87:343-349.
22. Påhlman L. Surgery and radiotherapy best in the treatment of rectal cancer: correct use of patient registries can further increase the quality [in Swedish]. Lakartidningen. 2000;97: 3564-3566.
23. Jorgren F, Johansson R, Damber L, Lindmark G. Risk factors of rectal cancer local recurrence: population-based survey and validation of the Swedish Rectal Cancer Registry. Colorectal Dis. 2009;12:977-986.
24. Sherif, Bintu N. A comparison of Kaplan-Meier and cumulative incidence estimate in the presence or absence of competing risks in breast cancer data. University of Pittsburgh. http://etd.library.pitt.edu/ETD/available/etd- 12032007-005529/. Statistics. Deposited April 1, 2009.
25. Graf W, Dahlberg M, Osman MM, Holmberg L, Påhlman L, Glimelius B. Short-term preoperative radiotherapy results in down-staging of rectal cancer: a study of 1316 patients. Radiother Oncol. 1997;43:133-137. (Pubitemid 27261581)
26. Holm T, Ljung A, Häggmark T, Jurell G, Lagergren J. Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer. Br J Surg. 2007;94: 232-238. (Pubitemid 46340406)
27. West NP, Finan PJ, Anderin C, Lindholm J, Holm T, Quirke P. Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer. J Clin Oncol. 2008;26: 3517-3522.
28. Martling A, Granath F, Cedermark B, Johansson R, Holm T. Gender differences in the treatment of rectal cancer: a population based study. Eur J Surg Oncol. 2009;35:427-433.
29. Colorectal Cancer Collaborative Group. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials. Lancet. 2001;358:1291-1304.
30. Glimelius B, Oliveira J; ESMO Guidelines Working Group. Rectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol. 2008;19:ii31-ii32.
31. Glimelius B. The role of radiotherapy in rectal cancer. Eur. J Cancer. 2001;37:S203-S212. (Pubitemid 33734652)
32. Quirke P, Steele R, Monson J, et al. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial. Lancet. 2009;373: 821-828.
33. Valentini V, Aristei C, Glimelius B, et al. Multidisciplinary rectal cancer management: 2nd European Rectal Cancer Consensus Conference (EURECA-CC2). Radiother Oncol. 2009;92:148-163.
34. Valentini V, Glimelius B. Rectal cancer radiotherapy: towards European consensus. Acta Oncol. 2010;49:1206-1216.