-
1
-
-
0036636074
-
Nucleic acid therapeutics: Basis principles and recent application
-
Opalinska, J. B., and Gewirtz, A. M. (2002) Nucleic acid therapeutics: basis principles and recent application. Nat. Rev. Drug Discov. 1, 503–514.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 503-514
-
-
Opalinska, J.B.1
Gewirtz, A.M.2
-
2
-
-
18744366905
-
Short-term and long-term modulation of gene expression by antisense therapeutics
-
Sazani, P., Vacek, M. M., and Kole, R. (2002) Short-term and long-term modulation of gene expression by antisense therapeutics. Curr. Opin. Biotechnol. 13, 468–472.
-
(2002)
Curr. Opin. Biotechnol.
, vol.13
, pp. 468-472
-
-
Sazani, P.1
Vacek, M.M.2
Kole, R.3
-
3
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello, C. C. (1988) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806–811.
-
(1988)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
4
-
-
3242677639
-
siR-NAs: Applications in functional genomics and potential as therapeutics
-
Dorsett, Y., and Tuschl, T. (2004) siR-NAs: applications in functional genomics and potential as therapeutics. Nat. Rev. Drug Discov. 3, 318–329.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
5
-
-
58749104364
-
The promises and pitfalls of RNA-interference-based therapeutics
-
Castanotto, D., and Rossi, J. J. (2009) The promises and pitfalls of RNA-interference-based therapeutics. Nature 457, 426–433.
-
(2009)
Nature
, vol.457
, pp. 426-433
-
-
Castanotto, D.1
Rossi, J.J.2
-
7
-
-
33748563173
-
Addressing the challenges of cellular delivery and bioavailability of peptide nucleic acids (PNA)
-
Nielsen, P. E. (2006) Addressing the challenges of cellular delivery and bioavailability of peptide nucleic acids (PNA). Q. Rev. Biophys. 38, 345–350.
-
(2006)
Q. Rev. Biophys.
, vol.38
, pp. 345-350
-
-
Nielsen, P.E.1
-
8
-
-
0027364174
-
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules
-
Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S. M., Driver, D. A., Berg, R. H., Kim, S. K., Norden, B., and Nielsen, P. E. (1993) PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature 365, 566–568.
-
(1993)
Nature
, vol.365
, pp. 566-568
-
-
Egholm, M.1
Buchardt, O.2
Christensen, L.3
Behrens, C.4
Freier, S.M.5
Driver, D.A.6
Berg, R.H.7
Kim, S.K.8
Norden, B.9
Nielsen, P.E.10
-
9
-
-
34447559636
-
Interfering with disease: A progress report on siRNA-based therapeutics
-
De Fougerolles, A., Vornlocher, H.-P., Maraganore, J., and Lieberman, J. (2007) Interfering with disease: a progress report on siRNA-based therapeutics. Nat. Rev. Drug Discov. 6, 443–453.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 443-453
-
-
de Fougerolles, A.1
Vornlocher, H.-P.2
Maraganore, J.3
Lieberman, J.4
-
10
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
Whitehead, K. A., Langer, R., and Anderson, D. G. (2009) Knocking down barriers: advances in siRNA delivery. Nat. Rev. Drug Discov. 8, 129–138.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
-
11
-
-
77649275761
-
Novel RNA-based strategies for therapeutic gene silencing
-
Sibley, C. R., Seow, Y., and Wood, M. J. (2010) Novel RNA-based strategies for therapeutic gene silencing. Mol. Ther. 18, 466–476.
-
(2010)
Mol. Ther.
, vol.18
, pp. 466-476
-
-
Sibley, C.R.1
Seow, Y.2
Wood, M.J.3
-
12
-
-
47249138782
-
Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
-
Juliano, R., Alam, M. R., Dixit, V., and Kang, H. (2008) Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res. 36, 4158–4171.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4158-4171
-
-
Juliano, R.1
Alam, M.R.2
Dixit, V.3
Kang, H.4
-
13
-
-
68549110328
-
Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics
-
Heitz, F., Morris, M. C., and Divita, G. (2009) Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics. Br. J. Pharmacol. 157, 195–206.
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 195-206
-
-
Heitz, F.1
Morris, M.C.2
Divita, G.3
-
14
-
-
67649408951
-
siRNA delivery using peptide transduction domains
-
Eguchi, A., and Dowdy, S. F. (2009) siRNA delivery using peptide transduction domains. Trends Pharmacol. Sci. 30, 341–345.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 341-345
-
-
Eguchi, A.1
Dowdy, S.F.2
-
15
-
-
27744557054
-
Cell-penetrating peptides: Mech-anisms and applications
-
El-Andaloussi, S., Holm, T., and Langel, U. (2005) Cell-penetrating peptides: mech-anisms and applications. Curr. Pharm. Des. 11, 3597–3611.
-
(2005)
Curr. Pharm. Des.
, vol.11
, pp. 3597-3611
-
-
El-Andaloussi, S.1
Holm, T.2
Langel, U.3
-
16
-
-
0031754150
-
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
-
Pooga, M., Soomets, U., Hallbrink, M., Valkna, A., Saar, K., Rezaei, K., Kahl, U., Hao, J. X., Xu, X. J., Wiesenfeld-Hallin, Z., Hokfelt, T., Bartfai, T., and Langel, U. (1998) Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat. Biotechnol. 16, 857–861.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 857-861
-
-
Pooga, M.1
Soomets, U.2
Hallbrink, M.3
Valkna, A.4
Saar, K.5
Rezaei, K.6
Kahl, U.7
Hao, J.X.8
Xu, X.J.9
Wiesenfeld-Hallin, Z.10
Hokfelt, T.11
Bartfai, T.12
Langel, U.13
-
17
-
-
38949206876
-
Cell penetrating peptide conjugates of steric block oligonucleotides
-
Lebleu, B., Moulton, H. M., Abes, R., Ivanova, G. D., Abes, S., Stein, C. A., Iversen, P. L., Arzumanov, A. A., and Gait, M. J. (2008) Cell penetrating peptide conjugates of steric block oligonucleotides. Adv. Drug Deliv. Rev. 60, 517–529.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 517-529
-
-
Lebleu, B.1
Moulton, H.M.2
Abes, R.3
Ivanova, G.D.4
Abes, S.5
Stein, C.A.6
Iversen, P.L.7
Arzumanov, A.A.8
Gait, M.J.9
-
18
-
-
77949890248
-
Cell penetrating peptides: Overview and applications to the delivery of oligonucleotides
-
Said Hassane, F., Saleh, A. F., Abes, R., Gait, M. J., and Lebleu, B. (2010) Cell penetrating peptides: overview and applications to the delivery of oligonucleotides. Cell Mol. Life Sci. 67, 715–26.
-
(2010)
Cell Mol. Life Sci.
, vol.67
, pp. 715-726
-
-
Said Hassane, F.1
Saleh, A.F.2
Abes, R.3
Gait, M.J.4
Lebleu, B.5
-
19
-
-
59849099411
-
Peptide-based Nanoparticles for ex vivo and in vivo drug delivery
-
Crombez, L., Morris, M. C., Deshayes, S., and Divita, G. (2008) Peptide-based Nanoparticles for ex vivo and in vivo drug delivery. Curr. Pharm. Des. 14, 3656–3665.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 3656-3665
-
-
Crombez, L.1
Morris, M.C.2
Deshayes, S.3
Divita, G.4
-
20
-
-
0037592877
-
Insight into the mechanism of the peptide-based gene delivery system MPG: Implications for delivery of siRNA into mammalian cells
-
Simeoni, F., Morris, M. C., Heitz, F., and Divita, G. (2003) Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells. Nucleic Acids Res. 31, 2717–2724.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2717-2724
-
-
Simeoni, F.1
Morris, M.C.2
Heitz, F.3
Divita, G.4
-
21
-
-
33748926761
-
Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development
-
Zeineddine, D., Papadimou, E., Chebli, K., Gineste, M., Liu, J., Grey, C., Thurig, S., Behfar, A., Wallace, V. A., Skerjanc, I. S., and Puceat, M. (2006) Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development. Dev. Cell 11, 535–546.
-
(2006)
Dev. Cell
, vol.11
, pp. 535-546
-
-
Zeineddine, D.1
Papadimou, E.2
Chebli, K.3
Gineste, M.4
Liu, J.5
Grey, C.6
Thurig, S.7
Behfar, A.8
Wallace, V.A.9
Skerjanc, I.S.10
Puceat, M.11
-
22
-
-
68149125757
-
Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth
-
Crombez, L., Morris, M. C., Dufort, S., Aldrian-Herrada, G., Nguyen, Q., Mc Master, G., Coll, J. L., Heitz, F., and Divita, G. (2009) Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth. Nucleic Acids Res. 37, 4559–4569.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4559-4569
-
-
Crombez, L.1
Morris, M.C.2
Dufort, S.3
Aldrian-Herrada, G.4
Nguyen, Q.5
Mc Master, G.6
Coll, J.L.7
Heitz, F.8
Divita, G.9
-
23
-
-
34249854268
-
A non-covalent peptide-based carrier for in vivo delivery of DNA mimics
-
Morris, M. C., Gros, E., Aldrian-Herrada, G., Choob, M., Archdeacon, J., Heitz, F., and Divita, G. (2007) A non-covalent peptide-based carrier for in vivo delivery of DNA mimics. Nucleic Acids Res. 35, e49–e59.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. e49-e59
-
-
Morris, M.C.1
Gros, E.2
Aldrian-Herrada, G.3
Choob, M.4
Archdeacon, J.5
Heitz, F.6
Divita, G.7
-
24
-
-
0035204427
-
A peptide carrier for the delivery of biologically active proteins into mammalian cells
-
Morris, M. C., Depollier, J., Mery, J., Heitz, F., and Divita, G. (2001) A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat. Biotechnol. 19, 1173–1176.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 1173-1176
-
-
Morris, M.C.1
Depollier, J.2
Mery, J.3
Heitz, F.4
Divita, G.5
-
25
-
-
0034839763
-
PNA-related oligonucleotide mimics and their evaluation for nucleic acid hybridization studies and analysis
-
Efimov, V., Choob, M., Buryakova, A., Phelan, D., and Chakhmakhcheva, O. (2001) PNA-related oligonucleotide mimics and their evaluation for nucleic acid hybridization studies and analysis. Nucleosides Nucleotides Nucleic Acids 20, 419–428.
-
(2001)
Nucleosides Nucleotides Nucleic Acids
, vol.20
, pp. 419-428
-
-
Efimov, V.1
Choob, M.2
Buryakova, A.3
Phelan, D.4
Chakhmakhcheva, O.5
-
26
-
-
38949184554
-
Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy
-
Deshayes, S., Morris, M., Heitz, F., and Divita, G. (2008) Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy. Adv. Drug Deliv. Rev. 60, 537–547.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 537-547
-
-
Deshayes, S.1
Morris, M.2
Heitz, F.3
Divita, G.4
-
27
-
-
0029859580
-
Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finas-teride
-
Umekita, Y., Hiipakka., R. A., Kokontis, J. M., and Liao, S. (1996) Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finas-teride. Proc. Natl. Acad. Sci. USA 93, 11802–11807.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11802-11807
-
-
Umekita, Y.1
Hiipakka, R.A.2
Kokontis, J.M.3
Liao, S.4
|