Tuning Wnt-signaling to enhance cardiomyogenesis in human embryonic and induced pluripotent stem cells

Journal of Molecular and Cellular Cardiology

Volumn 51, Issue 3, 2011, Pages 277-279

  Hudson, James E ^a   Zimmermann, Wolfram Hubertus ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

WNT PROTEIN;

CARDIOMYOGENESIS; CELL DIFFERENTIATION; DEVELOPMENTAL STAGE; EDITORIAL; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; HEART DEVELOPMENT; HEART MUSCLE CELL; HUMAN; IN VITRO STUDY; MESODERM; NONHUMAN; PALMITOYLATION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MYOCYTES, CARDIAC; WNT PROTEINS;

EID: 79960928175     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.06.011     Document Type: Editorial

References (18)

1. Chen B., Dodge M.E., Tang W., Lu J., Ma Z., Fan C.-W., et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol 2009, 5:100-107.
2. Kattman S.J., Witty A.D., Gagliardi M., Dubois N.C., Niapour M., Hotta A., et al. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell 2011, 8:228-240.
3. Paige S.L., Osugi T., Afanasiev O.K., Pabon L., Reinecke H., Murry C.E. Endogenous wnt/β-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS One 2010, 5:e11134.
4. Yang L., Soonpaa M.H., Adler E.D., Roepke T.K., Kattman S.J., Kennedy M., et al. Human cardiovascular progenitor cells develop from a KDR+embryonic-stem-cell-derived population. Nature 2008, 453:524-528.
5. Jackson S.A., Schiesser J., Stanley E.G., Elefanty A.G. Differentiating embryonic stem cells pass through temporal windows that mark responsiveness to exogenous and paracrine mesendoderm inducing signals. PLoS One 2010, 5:e10706.
6. Eisenberg L.M., Eisenberg C.A. Wnt signal transduction and the formation of the myocardium. Dev Biol 2006, 293:305-315.
7. Naito A.T., Shiojima I., Akazawa H., Hidaka K., Morisaki T., Kikuchi A., et al. Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis. PNAS. 2006, 103:19812-19817.
8. Takada R., Satomi Y., Kurata T., Ueno N., Norioka S., Kondoh H., et al. Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell 2006, 11:791-801.
9. 2+ wavefronts in mouse and human embryonic stem cell derived cardiomyocytes. Stem Cells Dev 2009, 18:1493-1500.
10. Satin J., Kehat I., Caspi O., Huber I., Arbel G., Itzhaki I., et al. Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes. J Physiol 2004, 559:479-496.
11. Mummery C., Ward-van Oostwaard D., Doevendans P., Spijker R., van den Brink S., Hassink R., et al. Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 2003, 107:2733-2740.
12. Kehat I., Kenyagin-Karsenti D., Snir M., Segev H., Amit M., Gepstein A., et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001, 108:407-414.
13. Satin J., Itzhaki I., Rapoport S., Schroder E.A., Izu L., Arbel G., et al. Calcium handling in human embryonic stem cell-derived cardiomyocytes. Stem Cells 2008, 26:1961-1972.
14. Binah O., Dolnikov K., Sadan O., Shilkrut M., Zeevi-Levin N., Amit M., et al. Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes. J Electrocardiol 2007, 40:S192-S196.
15. Itzhaki I., Maizels L., Huber I., Zwi-Dantsis L., Caspi O., Winterstern A., et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature 2011, 471:225-229.
16. Moretti A., Bellin M., Welling A., Jung C.B., Lam J.T., Bott-Flugel L., et al. Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med 2010, 363:1397-1409.
17. Carvajal-Vergara X., Sevilla A., D'Souza S.L., Ang Y.S., Schaniel C., Lee D.F., et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010, 465:808-812.
18. Nelson T.J., Martinez-Fernandez A., Terzic A. Induced pluripotent stem cells: developmental biology to regenerative medicine. Nat Rev Cardiol 2010, 7:700-710.