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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4698-4701

Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase

(9) Ducray, Richard a Simpson, Iain a Jung, Frederic H a Nissink, J Willem M a Kenny, Peter W a Fitzek, Martina a Walker, Graeme E a Ward, Lara T a Hudson, Kevin a

a ASTRAZENECA (United Kingdom)

Author keywords

IGF1 R; Insulin like growth factor 1 receptor; Tyrosine kinase inhibitor

Indexed keywords

BMS 754807; IMIDAZO[1,2 A]PYRIDINE DERIVATIVE; LINSITINIB; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG POTENCY; HIGH THROUGHPUT SCREENING; INHIBITION KINETICS; MOUSE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; DOGS; DRUG DISCOVERY; HUMANS; MICE; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; PYRIDINES; RATS; RECEPTOR, IGF TYPE 1; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 79960918946 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.06.093 Document Type: Article

Times cited : (48)

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