Calculation of configurational entropy with a boltzmann-quasiharmonic model: The origin of high-affinity protein-ligand binding

Journal of Physical Chemistry B

Volumn 115, Issue 30, 2011, Pages 9461-9472

  Harpole, Kyle W ^a   Sharp, Kim A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGANDS; PROTEINS;

BOLTZMANN EXPRESSION; COMPUTATIONAL DEMANDS; CONFIGURATIONAL ENTROPY; CONFORMATIONAL ENTROPY; ENTROPY CHANGES; FIRST-ORDER; LIGAND BINDING; PROTEIN COMPLEXES; PROTEIN MOTION; TEST MOLECULES;

ENTROPY;

EID: 79960913321     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp111176x     Document Type: Article

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