Ligand configurational entropy and protein binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 5, 2007, Pages 1534-1539

  Chang, Chia En A ^a   Chen, Wei ^b   Gilson, Michael K ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

Affinity; Drug design; Rotamer; Rotation; Translation

Indexed keywords

AMPRENAVIR; LIGAND; PROTEINASE;

ARTICLE; BINDING AFFINITY; CALCULATION; ENERGY TRANSFER; ENTROPY; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; ROTATION;

ALGORITHMS; ANTI-HIV AGENTS; CARBAMATES; DRUG DESIGN; ENTROPY; HIV PROTEASE; LIGANDS; MODELS, CHEMICAL; MODELS, STATISTICAL; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; SULFONAMIDES; THERMODYNAMICS;

EID: 33846822002     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610494104     Document Type: Article

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