Functional improvement of an IRQ-PEG-MEND for delivering genes to the lung

Journal of Controlled Release

Volumn 154, Issue 1, 2011, Pages 77-83

  Ishitsuka, Taichi ^a   Akita, Hidetaka ^a   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Active targeting; Endosomal escape; Endothelial cells; Gene delivery; Liposome

Indexed keywords

ACTIVE TARGETING; BIODISTRIBUTIONS; CATIONIC LIPIDS; CELLULAR UPTAKE; CORE PARTICLES; CRITICAL ISSUES; ENDOSOMAL ESCAPE; GENE DELIVERY; GENE DELIVERY SYSTEMS; IN-VIVO; INHIBITORY EFFECT; INTRACELLULAR TRAFFICKING; LIPID CHAINS; NANO DEVICE; NORMAL TISSUE; ORDERS OF MAGNITUDE; PEG SPACERS; PEGYLATION; PLASMID DNA; POLYCATIONS; TARGETED DELIVERY; TRANSGENE EXPRESSION; VASCULAR ENDOTHELIAL CELLS;

BIOLOGICAL ORGANS; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; LIGANDS; LIPOSOMES; MOLECULAR BIOLOGY; PEPTIDES; PHOSPHOLIPIDS; TISSUE;

ENDOTHELIAL CELLS;

IRQ PEPTIDE; LIPOSOME; MACROGOL; PEPTIDE; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE TARGETING; LUNG; MALE; MOUSE; MULTIFUNCTIONAL ENVELOPE TYPE NANO DEVICE; NANODEVICE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ANIMALS; CATIONS; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; INJECTIONS, INTRAVENOUS; LIPIDS; LIPOSOMES; LUCIFERASES, FIREFLY; LUNG; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; NANOSTRUCTURES; OLIGOPEPTIDES; PARTICLE SIZE; PLASMIDS; POLYETHYLENE GLYCOLS; SURFACE PROPERTIES; TISSUE DISTRIBUTION; TRANSFECTION; TRANSGENES;

EID: 79960911514     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.05.012     Document Type: Article

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