High-content analysis of CCR2 antagonists on human primary monocytes

Journal of Biomolecular Screening

Volumn 16, Issue 7, 2011, Pages 683-693

  Kredel, Simone ^a   Wolff, Michael ^b   Hobbie, Silke ^b   Bieler, Michael ^b   Gierschik, Peter ^a   Heilker, Ralf ^b  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

CCL2 internalization; CCR2; chemokine receptors; high content analysis; primary human monocytes

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR2 ANTAGONIST;

ALGORITHM; ARTICLE; BIOASSAY; CONTENT ANALYSIS; CONTROLLED STUDY; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; INTERNALIZATION; MONOCYTE; PRIORITY JOURNAL;

AUTOMATION, LABORATORY; CELL LINE, TUMOR; CHEMOKINE CCL2; FLUORESCENT DYES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; INTRACELLULAR SPACE; MONOCYTES; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, CCR2; STAINING AND LABELING;

EID: 79960904758     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111406884     Document Type: Article

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