-
1
-
-
2642526164
-
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
-
Azzouz M., Ralph G.S., Storkebaum E., Walmsley L.E., Mitrophanous K.A., Kingsman S.M., Carmeliet P., Mazarakis N.D. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 2004, 429:413-417.
-
(2004)
Nature
, vol.429
, pp. 413-417
-
-
Azzouz, M.1
Ralph, G.S.2
Storkebaum, E.3
Walmsley, L.E.4
Mitrophanous, K.A.5
Kingsman, S.M.6
Carmeliet, P.7
Mazarakis, N.D.8
-
2
-
-
33749056809
-
ALS: a disease of motor neurons and their nonnneuronal neighbors
-
Boillée S., Velde C.V., Cleveland D.W. ALS: a disease of motor neurons and their nonnneuronal neighbors. Neuron 2006, 52:39-59.
-
(2006)
Neuron
, vol.52
, pp. 39-59
-
-
Boillée, S.1
Velde, C.V.2
Cleveland, D.W.3
-
3
-
-
0035444173
-
Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice
-
Bordet T., Lesbordes J.C., Rouhani S., Castelnau-Ptakhine L., Schmalbruch H., Haase G., Kahn A. Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice. Hum Mol Genet 2001, 10:1925-1933.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1925-1933
-
-
Bordet, T.1
Lesbordes, J.C.2
Rouhani, S.3
Castelnau-Ptakhine, L.4
Schmalbruch, H.5
Haase, G.6
Kahn, A.7
-
4
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
Cleveland D.W., Rothstein J.D. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2001, 2:806-819.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
5
-
-
68349139704
-
Exercise induces metallothioneins in mouse spinal cord
-
Hashimoto K., Hayashi Y., Inuzuka T., Hozumi I. Exercise induces metallothioneins in mouse spinal cord. Neuroscience 2009, 163:244-251.
-
(2009)
Neuroscience
, vol.163
, pp. 244-251
-
-
Hashimoto, K.1
Hayashi, Y.2
Inuzuka, T.3
Hozumi, I.4
-
6
-
-
77951661535
-
Resistance of metallothionein-III null mice to cadmium-induced acute hepatotoxicity
-
Honda A., Komuro H., Hasegawa T., Seko Y., Shimada A., Nagase H., Hozumi I., Inuzuka T., Hara H., Fujiwara Y., Satoh M. Resistance of metallothionein-III null mice to cadmium-induced acute hepatotoxicity. J Toxicol Sci 2010, 35:209-215.
-
(2010)
J Toxicol Sci
, vol.35
, pp. 209-215
-
-
Honda, A.1
Komuro, H.2
Hasegawa, T.3
Seko, Y.4
Shimada, A.5
Nagase, H.6
Hozumi, I.7
Inuzuka, T.8
Hara, H.9
Fujiwara, Y.10
Satoh, M.11
-
7
-
-
77957875601
-
Attenuation of cadmium-induced testicular injury in metallothionein-III null mice
-
Honda A., Komuro H., Shimada A., Hasegawa T., Seko Y., Nagase H., Hozumi I., Inuzuka T., Hara H., Fujiwara Y., Satoh M. Attenuation of cadmium-induced testicular injury in metallothionein-III null mice. Life Sci 2010, 87:545-550.
-
(2010)
Life Sci
, vol.87
, pp. 545-550
-
-
Honda, A.1
Komuro, H.2
Shimada, A.3
Hasegawa, T.4
Seko, Y.5
Nagase, H.6
Hozumi, I.7
Inuzuka, T.8
Hara, H.9
Fujiwara, Y.10
Satoh, M.11
-
8
-
-
24744431646
-
Metallothioneins and neurodegenerative diseases
-
Hozumi I., Asanuma M., Hiraiwa M., Uchida Y. Metallothioneins and neurodegenerative diseases. J Health Sci 2004, 50:323-331.
-
(2004)
J Health Sci
, vol.50
, pp. 323-331
-
-
Hozumi, I.1
Asanuma, M.2
Hiraiwa, M.3
Uchida, Y.4
-
9
-
-
43549085481
-
Metallothionein-3 is expressed in the brain and various peripheral organs of the rat
-
Hozumi I., Suzuki J.S., Kanazawa H., Hara A., Saio M., Inuzuka T., Miyairi S., Naganuma A., Tohyama C. Metallothionein-3 is expressed in the brain and various peripheral organs of the rat. Neurosci Lett 2008, 438:54-58.
-
(2008)
Neurosci Lett
, vol.438
, pp. 54-58
-
-
Hozumi, I.1
Suzuki, J.S.2
Kanazawa, H.3
Hara, A.4
Saio, M.5
Inuzuka, T.6
Miyairi, S.7
Naganuma, A.8
Tohyama, C.9
-
10
-
-
32244434439
-
Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain
-
Hozumi I., Uchida Y., Watabe K., Sakamoto T., Inuzuka T. Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain. Neurosci Lett 2006, 395:220-223.
-
(2006)
Neurosci Lett
, vol.395
, pp. 220-223
-
-
Hozumi, I.1
Uchida, Y.2
Watabe, K.3
Sakamoto, T.4
Inuzuka, T.5
-
11
-
-
52649122792
-
The expression of metallothioneins is diminished in the spinal cords of patients with sporadic ALS
-
Hozumi I., Yamada M., Uchida Y., Ozawa K., Takahashi H., Inuzuka T. The expression of metallothioneins is diminished in the spinal cords of patients with sporadic ALS. Amyotroph Lateral Scler 2008, 9:294-298.
-
(2008)
Amyotroph Lateral Scler
, vol.9
, pp. 294-298
-
-
Hozumi, I.1
Yamada, M.2
Uchida, Y.3
Ozawa, K.4
Takahashi, H.5
Inuzuka, T.6
-
12
-
-
18744409323
-
Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords-screening by molecular indexing and subsequent cDNA microarray analysis
-
Ishigaki S., Niwa J., Ando Y., Yoshihara T., Sawada K., Doyu M., Yamamoto M., Kato K., Yotsumoto Y., Sobue G. Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords-screening by molecular indexing and subsequent cDNA microarray analysis. FEBS Lett 2002, 531:354-358.
-
(2002)
FEBS Lett
, vol.531
, pp. 354-358
-
-
Ishigaki, S.1
Niwa, J.2
Ando, Y.3
Yoshihara, T.4
Sawada, K.5
Doyu, M.6
Yamamoto, M.7
Kato, K.8
Yotsumoto, Y.9
Sobue, G.10
-
13
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
Kaspar B.K., Lladó J., Sherkat N., Rothstein J.D., Gage F.H. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 2003, 301:839-842.
-
(2003)
Science
, vol.301
, pp. 839-842
-
-
Kaspar, B.K.1
Lladó, J.2
Sherkat, N.3
Rothstein, J.D.4
Gage, F.H.5
-
14
-
-
0038103806
-
Regular exercise is beneficial to a mouse model of amyotrophic lateral sclerosis
-
Kirkinezos I.G., Hernandez D., Bradley W.G., Moraes C.T. Regular exercise is beneficial to a mouse model of amyotrophic lateral sclerosis. Ann Neurol 2003, 53:804-807.
-
(2003)
Ann Neurol
, vol.53
, pp. 804-807
-
-
Kirkinezos, I.G.1
Hernandez, D.2
Bradley, W.G.3
Moraes, C.T.4
-
15
-
-
34250209501
-
Amyotrophic lateral sclerosis
-
Mitchell J.D., Borasio G.D. Amyotrophic lateral sclerosis. Lancet 2007, 369:2031-2041.
-
(2007)
Lancet
, vol.369
, pp. 2031-2041
-
-
Mitchell, J.D.1
Borasio, G.D.2
-
16
-
-
0034047740
-
Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons
-
Montoliu C., Monfort P., Carrasco J., Palacios O., Capdevila M., Hidalgo J., Felipo V. Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons. J Neurochem 2000, 75:266-273.
-
(2000)
J Neurochem
, vol.75
, pp. 266-273
-
-
Montoliu, C.1
Monfort, P.2
Carrasco, J.3
Palacios, O.4
Capdevila, M.5
Hidalgo, J.6
Felipo, V.7
-
17
-
-
41149159534
-
Target muscles for retrograde gene delivery to specific spinal cord segments
-
Nakajima H., Uchida K., Kobayashi S., Inukai T., Yayama T., Sato R., Mwaka E., Baba H. Target muscles for retrograde gene delivery to specific spinal cord segments. Neurosci Lett 2008, 435:1-6.
-
(2008)
Neurosci Lett
, vol.435
, pp. 1-6
-
-
Nakajima, H.1
Uchida, K.2
Kobayashi, S.3
Inukai, T.4
Yayama, T.5
Sato, R.6
Mwaka, E.7
Baba, H.8
-
18
-
-
0037109771
-
Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins
-
Puttaparthi K., Gitomer W.L., Krishnan U., Son M., Rajendran B., Elliott J.L. Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins. J Neurosci 2002, 22:8790-8796.
-
(2002)
J Neurosci
, vol.22
, pp. 8790-8796
-
-
Puttaparthi, K.1
Gitomer, W.L.2
Krishnan, U.3
Son, M.4
Rajendran, B.5
Elliott, J.L.6
-
19
-
-
0028289610
-
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia
-
Quaife C.J., Findley S.D., Erickson J.C., Froelick G.J., Kelly E.J., Zambrowicz B.P., Palmiter R.D. Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry 1994, 33:7250-7259.
-
(1994)
Biochemistry
, vol.33
, pp. 7250-7259
-
-
Quaife, C.J.1
Findley, S.D.2
Erickson, J.C.3
Froelick, G.J.4
Kelly, E.J.5
Zambrowicz, B.P.6
Palmiter, R.D.7
-
20
-
-
85026146143
-
Growth inhibitory factor prevents degeneration of injured adult rat motoneurons
-
Sakamoto T., Kawazoe Y., Uchida Y., Hozumi I., Inuzuka T., Watabe K. Growth inhibitory factor prevents degeneration of injured adult rat motoneurons. Neuroreport 2003, 14:2147-2151.
-
(2003)
Neuroreport
, vol.14
, pp. 2147-2151
-
-
Sakamoto, T.1
Kawazoe, Y.2
Uchida, Y.3
Hozumi, I.4
Inuzuka, T.5
Watabe, K.6
-
21
-
-
58149242839
-
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
-
Sorenson E.J., Windbank A.J., Mandrekar J.N., Bamlet W.R., Appel S.H., Armon C., Barkhaus P.E., Bosch P., Boylan K., David W.S., Feldman E., Glass J., Gutmann L., Katz J., King W., Luciano C.A., McCluskey L.F., Nash S., Newman D.S., Pascuzzi R.M., Pioro E., Sams L.J., Scelsa S., Simpson E.P., Subramony S.H., Tiryaki E., Thornton C.A. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology 2008, 71:1770-1775.
-
(2008)
Neurology
, vol.71
, pp. 1770-1775
-
-
Sorenson, E.J.1
Windbank, A.J.2
Mandrekar, J.N.3
Bamlet, W.R.4
Appel, S.H.5
Armon, C.6
Barkhaus, P.E.7
Bosch, P.8
Boylan, K.9
David, W.S.10
Feldman, E.11
Glass, J.12
Gutmann, L.13
Katz, J.14
King, W.15
Luciano, C.A.16
McCluskey, L.F.17
Nash, S.18
Newman, D.S.19
Pascuzzi, R.M.20
Pioro, E.21
Sams, L.J.22
Scelsa, S.23
Simpson, E.P.24
Subramony, S.H.25
Tiryaki, E.26
Thornton, C.A.27
more..
-
22
-
-
33845289424
-
Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis
-
Tokuda E., Ono S., Ishige K., Naganuma A., Ito Y., Suzuki T. Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis. Toxicology 2007, 229:33-41.
-
(2007)
Toxicology
, vol.229
, pp. 33-41
-
-
Tokuda, E.1
Ono, S.2
Ishige, K.3
Naganuma, A.4
Ito, Y.5
Suzuki, T.6
-
23
-
-
0037200013
-
Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging
-
32353-32259
-
Uchida Y., Gomi F., Masumizu T., Miura Y. Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging. J Biol Chem 2002, 277. 32353-32259.
-
(2002)
J Biol Chem
, vol.277
-
-
Uchida, Y.1
Gomi, F.2
Masumizu, T.3
Miura, Y.4
-
24
-
-
0025768860
-
The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein
-
Uchida Y., Takio K., Titani K., Ihara Y., Tomonaga M. The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Neuron 1991, 7:337-347.
-
(1991)
Neuron
, vol.7
, pp. 337-347
-
-
Uchida, Y.1
Takio, K.2
Titani, K.3
Ihara, Y.4
Tomonaga, M.5
-
25
-
-
0037104725
-
Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis
-
Wang L.J., Lu Y.Y., Muramatsu S., Ikeguchi K., Fujimoto K., Okada T., Mizukami H., Matsushita T., Hanazono Y., Kume A., Nagatsu T., Ozawa K., Nakano I. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis. J Neurosci 2002, 22:6920-6928.
-
(2002)
J Neurosci
, vol.22
, pp. 6920-6928
-
-
Wang, L.J.1
Lu, Y.Y.2
Muramatsu, S.3
Ikeguchi, K.4
Fujimoto, K.5
Okada, T.6
Mizukami, H.7
Matsushita, T.8
Hanazono, Y.9
Kume, A.10
Nagatsu, T.11
Ozawa, K.12
Nakano, I.13
-
26
-
-
21444451106
-
Gait analysis detects early changes in transgenic SOD1(G93A) mice
-
Wooley C.M., Sher R.B., Kale A., Frankel W.N., Cox G.A., Seburn K.L. Gait analysis detects early changes in transgenic SOD1(G93A) mice. Muscle Nerve 2005, 32:43-50.
-
(2005)
Muscle Nerve
, vol.32
, pp. 43-50
-
-
Wooley, C.M.1
Sher, R.B.2
Kale, A.3
Frankel, W.N.4
Cox, G.A.5
Seburn, K.L.6
|