Genetically engineered stem cells expressing cytosine deaminase and interferon-β migrate to human lung cancer cells and have potentially therapeutic anti-tumor effects

International Journal of Oncology

Volumn 39, Issue 4, 2011, Pages 833-839

  Yi, Bo Rim ^a   O, Si Na ^a   Kang, Nam Hee ^a   Hwang, Kyung A ^a   Kim, Seung U ^b   Jeung, Eui Bae ^a   Kim, Yun Bae ^a   Heo, Gang Joon ^a   Choi, Kyung Chul ^a  

^a Chungbuk National University   (South Korea)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cytosine deaminase; Interferon ; Lung cancer; Therapeutic stem cells; Tumor tropism

Indexed keywords

BETA INTERFERON; CHEMOKINE RECEPTOR CXCR4; CYTOSINE DEAMINASE; FLUCYTOSINE; SCATTER FACTOR; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CONTROLLED STUDY; DRUG TARGETING; FUSION GENE; GENE DIRECTED ENZYME PRODRUG THERAPY; GENE EXPRESSION; GENETIC ENGINEERING; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CANCER; PRIORITY JOURNAL; STEM CELL; SUICIDE GENE;

CARCINOMA, NON-SMALL-CELL LUNG; CELL COMMUNICATION; CELL LINE, TUMOR; CELL MIGRATION ASSAYS; CELL MOVEMENT; CHEMOTACTIC FACTORS; CYTOSINE DEAMINASE; DRUG DELIVERY SYSTEMS; FLUCYTOSINE; FLUOROURACIL; GENE THERAPY; GENETIC ENGINEERING; HUMANS; INTERFERON-BETA; LUNG NEOPLASMS; PRODRUGS; STEM CELLS;

EID: 79960885800     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1126     Document Type: Article

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