A single amino acid of human immunodeficiency virus type 2 capsid protein affects conformation of two external loops and viral sensitivity to TRIM5α

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Miyamoto, Tadashi ^a   Yokoyama, Masaru ^b   Kono, Ken ^a,c   Shioda, Tatsuo ^a   Sato, Hironori ^b   Nakayama, Emi E ^a  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARTIC ACID; CAPSID PROTEIN; GLUTAMIC ACID; TRIPARTITE MOTIF PROTEIN 5; PROTEIN; TRIM5(ALPHA) PROTEIN, RHESUS MONKEY;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 2; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; NONHUMAN; PROBABILITY; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS; VIRUS MUTANT; VIRUS RESISTANCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MACACA FASCICULARIS; METABOLISM; SIMIAN IMMUNODEFICIENCY VIRUS; SITE DIRECTED MUTAGENESIS; VIROLOGY; VIRUS REPLICATION; WESTERN BLOTTING;

HUMAN IMMUNODEFICIENCY VIRUS 2; MACACA FASCICULARIS; MIRIDAE;

AMINO ACID SUBSTITUTION; ANIMALS; BLOTTING, WESTERN; CAPSID PROTEINS; HIV INFECTIONS; HIV-1; HIV-2; HUMANS; MACACA FASCICULARIS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEINS; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

EID: 79960855403     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022779     Document Type: Article

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