Volume depletion versus dehydration: How understanding the difference can guide therapy

American Journal of Kidney Diseases

Volumn 58, Issue 2, 2011, Pages 302-309

  Bhave, Gautam ^a   Neilson, Eric G ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

dehydration; hyperglycemic hypertonic nonketosis (HHNK); Hypertonicity; volume depletion

Indexed keywords

CALCIUM; HYPERTONIC SOLUTION; SODIUM;

ADULT; ARTICLE; BLOOD PRESSURE; BODY FLUID; CASE REPORT; CONFUSION; DEHYDRATION; EXTRACELLULAR SPACE; FLUID THERAPY; GLUCOSE BLOOD LEVEL; HUMAN; MALE; MORBID OBESITY; NAUSEA; PATHOPHYSIOLOGY; PULSE RATE; SODIUM BLOOD LEVEL; SPORTS DRINK; VOLUME DEPLETION; VOMITING;

ADULT; DEHYDRATION; EXTRACELLULAR FLUID; FLUID THERAPY; HUMANS; MALE; TERMINOLOGY AS TOPIC;

EID: 79960846060     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2011.02.395     Document Type: Article

References (62)

1. W.C. Chumlea, S.S. Guo, and C.M. Zeller Total body water reference values and prediction equations for adults Kidney Int 59 6 2001 2250 2258 (Pubitemid 32467618)
2. P.E. Watson, I.D. Watson, and R.D. Batt Total body water volumes for adult males and females estimated from simple anthropometric measurements Am J Clin Nutr 33 1 1980 27 39 (Pubitemid 10141676)
3. I.S. Edelman, and J. Leibman Anatomy of body water and electrolytes Am J Med 27 1959 256 277
4. I.S. Edelman, J. Leibman, M.P. O'Meara, and L.W. Birkenfeld Interrelations between serum sodium concentration, serum osmolarity and total exchangeable sodium, total exchangeable potassium and total body water J Clin Invest 37 9 1958 1236 1256
5. F.J. Gennari Current concepts Serum osmolality. Uses and limitations N Engl J Med 310 2 1984 102 105 (Pubitemid 14214868)
6. K. Mange, D. Matsuura, and B. Cizman Language guiding therapy: the case of dehydration versus volume depletion Ann Intern Med 127 9 1997 848 853 (Pubitemid 27465560)
7. M. Goldberg Hyponatremia Med Clin North Am 65 2 1981 251 269 (Pubitemid 11080205)
8. T. Berl Impact of solute intake on urine flow and water excretion J Am Soc Nephrol 19 6 2008 1076 1078
9. E. Ferrannini, J.D. Smith, C. Cobelli, G. Toffolo, A. Pilo, and R.A. DeFronzo Effect of insulin on the distribution and disposition of glucose in man J Clin Invest 76 1 1985 357 364 (Pubitemid 15243464)
10. J.A. Jacquez Theory of production rate calculations in steady and non-steady states and its application to glucose metabolism Am J Physiol 262 6, pt 1 1992 E779 E790
11. M.A. Katz Hyperglycemia-induced hyponatremiacalculation of expected serum sodium depression N Engl J Med 289 16 1973 843 844
12. M.S. Oh Pathogenesis and diagnosis of hyponatremia Nephron 92 suppl 1 2002 2 8 (Pubitemid 36151475)
13. S.M. Moran, and R.L. Jamison The variable hyponatremic response to hyperglycemia West J Med 142 1 1985 49 53 (Pubitemid 15127484)
14. A.H. Tzamaloukas, T.S. Ing, and K.C. Siamopoulos Body fluid abnormalities in severe hyperglycemia in patients on chronic dialysis: review of published reports J Diabetes Complications 22 1 2008 29 37
15. R.W. Schrier Decreased effective blood volume in edematous disorders: what does this mean? J Am Soc Nephrol 18 7 2007 2028 2031 (Pubitemid 47041067)
16. O.H. Gauer, J.P. Henry, and C. Behn The regulation of extracellular fluid volume Annu Rev Physiol 32 1970 547 595
17. W.R. Drucker, C.D. Chadwick, and D.S. Gann Transcapillary refill in hemorrhage and shock Arch Surg 116 10 1981 1344 1353 (Pubitemid 11004858)
18. S. Ishibe, and A.J. Peixoto Methods of assessment of volume status and intercompartmental fluid shifts in hemodialysis patients: implications in clinical practice Semin Dial 17 1 2004 37 43 (Pubitemid 38376690)
19. R.V. Ebert, E.A. Stead, and J.G. Gibson Response of normal man to acute blood loss Arch Intern Med 68 3 1941 578 590
20. H.A. Koomans, A.B. Geers, and E.J. Mees Plasma volume recovery after ultrafiltration in patients with chronic renal failure Kidney Int 26 6 1984 848 854 (Pubitemid 15197006)
21. F.D. Moore The effects of hemorrhage on body composition N Engl J Med 273 1965 567 577
22. L. Riddez, R.G. Hahn, B. Brismar, A. Strandberg, C. Svensen, and G. Hedenstierna Central and regional hemodynamics during acute hypovolemia and volume substitution in volunteers Crit Care Med 25 4 1997 635 640 (Pubitemid 27193976)
23. S.M. Kavic, E.J. Frehm, and A.S. Segal Case studies in cholera: lessons in medical history and science Yale J Biol Med 72 6 1999 393 408 (Pubitemid 32006402)
24. T.L. Grayson, J.E. White, and C.A. Moyer Oxygen consumptions; concentrations of inorganic ions in urine, serum and duodenal fluid, hematocrits, urinary excretions; pulse rates and blood pressure during duodenal depletions of sodium salts in normal and alcoholic man Ann Surg 158 1963 840 858
25. F.C. Reubi Hemodynamic changes in isotonic dehydration Contrib Nephrol 21 1980 55 61
26. M.H. Harrison Effects on thermal stress and exercise on blood volume in humans Physiol Rev 65 1 1985 149 209 (Pubitemid 15165387)
27. P.U. Feig, and D.K. McCurdy The hypertonic state N Engl J Med 297 26 1977 1444 1454
28. R. Knopp, R. Claypool, and D. Leonardi Use of the tilt test in measuring acute blood loss Ann Emerg Med 9 2 1980 72 75 (Pubitemid 10093492)
29. S. McGee, W.B. Abernethy III, and D.L. Simel The rational clinical examination Is this patient hypovolemic? JAMA 281 11 1999 1022 1029
30. R.A. McCance Medical problems in mineral metabolism III. Experimental human salt deficiency Lancet 227 5876 1936 823 830
31. R.A. McCance The effect of salt deficiency in man on the volume of the extracellular fluids, and on the composition of sweat, saliva, gastric juice and cerebrospinal fluid J Physiol 92 2 1938 208 218
32. R.A. McCance, and E.M. Widdowson The secretion of urine in man during experimental salt deficiency J Physiol 91 2 1937 222 231
33. R.A. McCance, W.F. Young, and D.A. Black The secretion of urine during dehydration and rehydration J Physiol 102 4 1944 415 428
34. J.W. Nadal, S. Pedersen, and W.G. Maddock A comparison between dehydration from salt loss and from water deprivation J Clin Invest 20 6 1941 691 703
35. K.F. Badr, and I. Ichikawa Prerenal failure: a deleterious shift from renal compensation to decompensation N Engl J Med 319 10 1988 623 629
36. H.D. Lauson, S.E. Bradley, A. Cournand, and V.V. Andrews The renal circulation in shock J Clin Invest 23 3 1944 381 402
37. T.A. Lombardo, S. Eisenberg, B.B. Oliver, W.N. Viar, E.E. Eddleman Jr, and T.R. Harrison Effects of bleeding on electrolyte excretion and on glomerular filtration Circulation 3 2 1951 260 270
38. A.M. Stone, and W.M. Stahl Renal effects of hemorrhage in normal man Ann Surg 172 5 1970 825 836
39. W.S. Wiggins, C.H. Manry, R.H. Lyons, and R.F. Pitts The effect of salt loading and salt depletion on renal function and electrolyte excretion in man Circulation 3 2 1951 275 281
40. E.K. Hoffmann, I.H. Lambert, and S.F. Pedersen Physiology of cell volume regulation in vertebrates Physiol Rev 89 1 2009 193 277
41. M.L. McManus, K.B. Churchwell, and K. Strange Regulation of cell volume in health and disease N Engl J Med 333 19 1995 1260 1266
42. R. Matz Management of the hyperosmolar hyperglycemic syndrome Am Fam Physician 60 5 1999 1468 1476 (Pubitemid 29498212)
43. D.K. McCurdy Hyperosmolar hyperglycemic nonketotic diabetic coma Med Clin North Am 54 3 1970 683 699
44. A.S. Pollock, and A.I. Arieff Abnormalities of cell volume regulation and their functional consequences Am J Physiol 239 3 1980 F195 F205
45. P. Zeitler, A. Haqq, A. Rosenbloom, N. Glaser Drugs and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society Hyperglycemic hyperosmolar syndrome in children: pathophysiological considerations and suggested guidelines for treatment J Pediatr 158 1 2011 9 14 14.e1-2
46. A.E. Kitabchi, G.E. Umpierrez, J.M. Miles, and J.N. Fisher Hyperglycemic crises in adult patients with diabetes Diabetes Care 32 7 2009 1335 1343
47. L. Bankir, N. Bouby, M.M. Trinh-Trang-Tan, M. Ahloulay, and D. Promeneur Direct and indirect cost of urea excretion Kidney Int 49 6 1996 1598 1607 (Pubitemid 26186587)
48. A. Leaf Dehydration in elderly N Engl J Med 311 12 1984 791 792 20
49. C.C. Carpenter Skin turgor Lancet 1 8221 1981 675
50. K.L. Dorrington Skin turgor: do we understand the clinical sign? Lancet 1 8214 1981 264 266
51. T. Hew-Butler, T.D. Noakes, S.J. Soldin, and J.G. Verbalis Acute changes in arginine vasopressin, sweat, urine and serum sodium concentrations in exercising humans: does a coordinated homeostatic relationship exist? Br J Sports Med 44 10 2010 710 715
52. N.P. Walsh, J.C. Montague, N. Callow, and A.V. Rowlands Saliva flow rate, total protein concentration and osmolality as potential markers of whole body hydration status during progressive acute dehydration in humans Arch Oral Biol 49 2 2004 149 154 (Pubitemid 38157578)
53. J. Lapides, R.B. Bourne, and L.R. Maclean Clinical signs of dehydration and extracellular fluid loss JAMA 191 1965 413 415
54. T.R. Miller, R.J. Anderson, and S.L. Linas Urinary diagnostic indices in acute renal failure: a prospective study Ann Intern Med 89 1 1978 47 50 (Pubitemid 8390144)
55. D.W. Atchley, R.F. Loeb, D.W. Richards, E.M. Benedict, and M.E. Driscoll On diabetic acidosis: a detailed study of electrolyte balances following the withdrawal and reestablishment of insulin therapy J Clin Invest 12 2 1933 297 326
56. W.A. Brodsky, S. Rapoport, and C.D. West The mechanism of glycosuric diuresis in diabetic man J Clin Invest 29 8 1950 1021 1032
57. D.W. Seldin, and R. Tarail The metabolism of glucose and electrolytes in diabetic acidosis J Clin Invest 29 5 1950 552 565
58. F.J. Gennari, and J.P. Kassirer Osmotic diuresis N Engl J Med 291 14 1974 714 720
59. B.D. Rose New approach to disturbances in the plasma sodium concentration Am J Med 81 6 1986 1033 1040
60. A.H. Tzamaloukas, T.S. Ing, and K.C. Siamopoulos Pathophysiology and management of fluid and electrolyte disturbances in patients on chronic dialysis with severe hyperglycemia Semin Dial 21 5 2008 431 439
61. N.R. Rosenthal, and E.J. Barrett An assessment of insulin action in hyperosmolar hyperglycemic nonketotic diabetic patients J Clin Endocrinol Metab 60 3 1985 607 610 (Pubitemid 15133868)
62. H.J. Adrogue, and N.E. Madias Hypernatremia N Engl J Med 342 20 2000 1493 1499 (Pubitemid 30318274)