Clinical significance of circulating tumor cells in breast cancer patients

Breast Cancer Research and Treatment

Volumn 129, Issue 1, 2011, Pages 247-254

  Tao, Min ^a   Ma, Deliang ^a   Li, Yan ^a,b   Zhou, Chong ^a   Zhang, Yinsheng ^b   Duan, Weiming ^a   Xu, Xiujuan ^a   Wang, Rong ^a   Wu, Lingzhi ^a   Liu, Haiyan ^b  

^a SOOCHOW UNIVERSITY   (China)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

Breast cancer; Circulating tumor cells; Laser scanning cytometry

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2;

ACCURACY; ADULT; AGED; ARTICLE; BREAST CANCER; CANCER STAGING; CELL COUNT; CELL SEPARATION; CIRCULATING TUMOR CELL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DRUG EFFICACY; HUMAN; HUMAN CELL; LASER SCANNING CYTOMETRY; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME;

ADULT; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; LASER SCANNING CYTOMETRY; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; NEOPLASTIC CELLS, CIRCULATING; PROGNOSIS; REPRODUCIBILITY OF RESULTS;

EID: 79960846056     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1512-4     Document Type: Article

References (33)

1. K Pantel RH Brakenhoff 2004 Dissecting the metastatic cascade Nat Rev Cancer 4 6 448 456 15170447 10.1038/nrc1370 1:CAS:528:DC%2BD2cXksVaisbY%3D (Pubitemid 38745530)
2. S Sleijfer JW Gratama AM Sieuwerts, et al. 2007 Circulating tumour cell detection on its way to routine diagnostic implementation? Eur J Cancer 43 18 2645 2650 17977713 10.1016/j.ejca.2007.09.016 1:CAS:528:DC%2BD2sXhsVSgs7nM (Pubitemid 350151847)
3. DF Hayes J Smerage 2008 Is there a role for circulating tumor cells in the management of breast cancer? Clin Cancer Res 14 12 3646 3650 18559576 10.1158/1078-0432.CCR-07-4481 1:CAS:528:DC%2BD1cXntlWkurg%3D
4. K Pantel S Riethdorf 2009 Pathology: are circulating tumor cells predictive of overall survival? Nat Rev Clin Oncol 6 4 190 191 19333222 10.1038/nrclinonc.2009.23
5. Z Panteleakou P Lembessis A Sourla, et al. 2009 Detection of circulating tumor cells in prostate cancer patients: methodological pitfalls and clinical relevance Mol Med 15 3-4 101 114 19081770 1:CAS:528:DC%2BD1MXnvF2lsrY%3D
6. AE Ring L Zabaglo MG Ormerod, et al. 2005 Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques Br J Cancer 92 5 906 912 15714202 10.1038/sj.bjc.6602418 1:STN:280:DC%2BD2M7isVKitQ%3D%3D (Pubitemid 40462638)
7. L Zabaglo MG Ormerod M Parton, et al. 2003 Cell filtration-laser scanning cytometry for the characterisation of circulating breast cancer cells Cytometry A 55 2 102 108 14505315 10.1002/cyto.a.10071 (Pubitemid 37522512)
8. M Cristofanilli GT Budd MJ Ellis, et al. 2004 Circulating tumor cells, disease progression, and survival in metastatic breast cancer N Engl J Med 351 8 781 791 15317891 10.1056/NEJMoa040766 1:CAS:528:DC%2BD2cXntVeitb4%3D (Pubitemid 39095313)
9. U De Giorgi V Valero E Rohren, et al. 2009 Circulating tumor cells and [18F]fluorodeoxyglucose positron emission tomography/computed tomography for outcome prediction in metastatic breast cancer J Clin Oncol 27 20 3303 3311 19451443 10.1200/JCO.2008.19.4423
10. JS de Bono HI Scher RB Montgomery, et al. 2008 Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer Clin Cancer Res 14 19 6302 6309 18829513 10.1158/1078-0432.CCR- 08-0872
11. SJ Cohen CJ Punt N Iannotti, et al. 2008 Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer J Clin Oncol 26 19 3213 3221 18591556 10.1200/JCO.2007.15.8923
12. M Cristofanilli DF Hayes GT Budd, et al. 2005 Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer J Clin Oncol 23 7 1420 1430 15735118 10.1200/JCO.2005.08.140
13. K Pachmann R Dengler K Lobodasch, et al. 2008 An increase in cell number at completion of therapy may develop as an indicator of early relapse: quantification of circulating epithelial tumor cells (CETC) for monitoring of adjuvant therapy in breast cancer J Cancer Res Clin Oncol 134 1 59 65 17611779 10.1007/s00432-007-0248-3 (Pubitemid 350060685)
14. T Bauernhofer S Zenahlik G Hofmann, et al. 2005 Association of disease progression and poor overall survival with detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer Oncol Rep 13 2 179 184 15643496
15. S Riethdorf H Fritsche V Muller, et al. 2007 Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system Clin Cancer Res 13 3 920 928 17289886 10.1158/1078-0432.CCR-06-1695 1:CAS:528:DC%2BD2sXhsVyrsL0%3D (Pubitemid 46340368)
16. K Pachmann 2005 Longtime recirculating tumor cells in breast cancer patients Clin Cancer Res 11 15 5657 16061886 10.1158/1078-0432.CCR-05-0191 author reply 5657-5658 (Pubitemid 41060846)
17. B Naume E Borgen K Beiske, et al. 1997 Immunomagnetic techniques for the enrichment and detection of isolated breast carcinoma cells in bone marrow and peripheral blood J Hematother 6 2 103 114 9131439 10.1089/scd.1.1997.6.103 1:STN:280:DyaK2s3nvVWjtw%3D%3D
18. E Racila D Euhus AJ Weiss, et al. 1998 Detection and characterization of carcinoma cells in the blood Proc Natl Acad Sci USA 95 8 4589 4594 9539782 10.1073/pnas.95.8.4589 1:CAS:528:DyaK1cXis1OgsLg%3D (Pubitemid 28207957)
19. JY Pierga C Bonneton A Vincent-Salomon, et al. 2004 Clinical significance of immunocytochemical detection of tumor cells using digital microscopy in peripheral blood and bone marrow of breast cancer patients Clin Cancer Res 10 4 1392 1400 14977842 10.1158/1078-0432.CCR-0102-03 1:CAS:528:DC%2BD2cXhsVGjsLw%3D (Pubitemid 38365234)
20. L Zhou K Wang W Tan, et al. 2006 Quantitative intracellular molecular profiling using a one-dimensional flow system Anal Chem 78 17 6246 6251 16944908 10.1021/ac060598e 1:CAS:528:DC%2BD28Xnt12ntL4%3D (Pubitemid 44360139)
21. S Nagrath LV Sequist S Maheswaran, et al. 2007 Isolation of rare circulating tumour cells in cancer patients by microchip technology Nature 450 7173 1235 1239 18097410 10.1038/nature06385 1:CAS:528:DC%2BD2sXhsVGjsL%2FK
22. L Su PR Morgan EB Lane 1996 Expression of cytokeratin messenger RNA versus protein in the normal mammary gland and in breast cancer Hum Pathol 27 8 800 806 8760013 10.1016/S0046-8177(96)90452-9 1:STN:280:DyaK28zis1KmsQ%3D%3D (Pubitemid 26287221)
23. S Bonin D Brunetti E Benedetti, et al. 2008 Molecular characterisation of breast cancer patients at high and low recurrence risk Virchows Arch 452 3 241 250 18236071 10.1007/s00428-007-0570-9 1:CAS:528:DC%2BD1cXmtFGntLc%3D
24. B Willipinski-Stapelfeldt S Riethdorf V Assmann, et al. 2005 Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells Clin Cancer Res 11 22 8006 8014 16299229 10.1158/1078-0432.CCR-05-0632 1:CAS:528:DC%2BD2MXht1entr7K (Pubitemid 41698741)
25. O Zach D Lutz 2006 Tumor cell detection in peripheral blood and bone marrow Curr Opin Oncol 18 1 48 56 16357564 10.1097/01.cco.0000198973.51615.fa (Pubitemid 43740450)
26. JE Lang K Mosalpuria M Cristofanilli, et al. 2009 HER2 status predicts the presence of circulating tumor cells in patients with operable breast cancer Breast Cancer Res Treat 113 3 501 507 18327638 10.1007/s10549-008-9951-2 1:CAS:528:DC%2BD1MXotVamtQ%3D%3D
27. GT Budd M Cristofanilli MJ Ellis, et al. 2006 Circulating tumor cells versus imaging-predicting overall survival in metastatic breast cancer Clin Cancer Res 12 21 6403 6409 17085652 10.1158/1078-0432.CCR-05-1769 1:CAS:528:DC%2BD28XhtFKitb%2FJ (Pubitemid 44799711)
28. JE Lang CS Hall B Singh, et al. 2007 Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: research tool or clinical application? Expert Rev Anticancer Ther 7 10 1463 1472 17944570 10.1586/14737140.7.10.1463 (Pubitemid 351826911)
29. N Xenidis M Perraki M Kafousi, et al. 2006 Predictive and prognostic value of peripheral blood cytokeratin-19 mRNA-positive cells detected by real-time polymerase chain reaction in node-negative breast cancer patients J Clin Oncol 24 23 3756 3762 16769987 10.1200/JCO.2005.04.5948 1:CAS:528:DC%2BD28XpsVaqs78%3D (Pubitemid 46622314)
30. JJ Gaforio MJ Serrano P Sanchez-Rovira, et al. 2003 Detection of breast cancer cells in the peripheral blood is positively correlated with estrogen-receptor status and predicts for poor prognosis Int J Cancer 107 6 984 990 14601059 10.1002/ijc.11479 1:CAS:528:DC%2BD3sXptFOgtb8%3D (Pubitemid 37429841)
31. IH Benoy H Elst M Philips, et al. 2006 Real-time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer Br J Cancer 94 5 672 680 16495933 1:STN:280:DC%2BD287mtFegsA%3D%3D (Pubitemid 43361898)
32. EN Stathopoulos E Sanidas M Kafousi, et al. 2005 Detection of CK-19 mRNA-positive cells in the peripheral blood of breast cancer patients with histologically and immunohistochemically negative axillary lymph nodes Ann Oncol 16 2 240 246 15668277 10.1093/annonc/mdi043 1:STN:280:DC%2BD2M%2FjvFyitg%3D%3D (Pubitemid 40309303)
33. S Braun FD Vogl B Naume, et al. 2005 A pooled analysis of bone marrow micrometastasis in breast cancer N Engl J Med 353 8 793 802 16120859 10.1056/NEJMoa050434 1:CAS:528:DC%2BD2MXovVKlu7s%3D (Pubitemid 41215488)