메뉴 건너뛰기




Volumn 309, Issue 2, 2011, Pages 199-208

RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling

Author keywords

Akt; Cyclin; GAIP; PI3K; RGS19

Indexed keywords

CYCLIN D1; CYCLIN D3; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAD; PROTEIN KINASE B; RAF PROTEIN; RETINOBLASTOMA PROTEIN; RGS PROTEIN; RGS19 PROTEIN; TUBERIN; UNCLASSIFIED DRUG;

EID: 79960845213     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.06.002     Document Type: Article
Times cited : (27)

References (44)
  • 1
    • 0031893949 scopus 로고    scopus 로고
    • The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades
    • Gutkind S.J. The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades. J. Biol. Chem. 1998, 273:1839-1842.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1839-1842
    • Gutkind, S.J.1
  • 2
    • 65549119281 scopus 로고    scopus 로고
    • Regulation of transcription factors by heterotrimeric G proteins
    • Ho M.K.C., Su Y., Yeung W.W.S., Wong Y.H. Regulation of transcription factors by heterotrimeric G proteins. Curr. Mol. Pharmacol. 2009, 2:19-31.
    • (2009) Curr. Mol. Pharmacol. , vol.2 , pp. 19-31
    • Ho, M.K.C.1    Su, Y.2    Yeung, W.W.S.3    Wong, Y.H.4
  • 3
    • 34250814224 scopus 로고    scopus 로고
    • Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression
    • New D.C., Wong Y.H. Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression. J. Mol. Signal 2007, 2:2.
    • (2007) J. Mol. Signal , vol.2 , pp. 2
    • New, D.C.1    Wong, Y.H.2
  • 5
    • 0036733358 scopus 로고    scopus 로고
    • Cellular regulation of RGS proteins: modulators and integrators of G protein signalling
    • Hollinger S., Hepler J.R. Cellular regulation of RGS proteins: modulators and integrators of G protein signalling. Pharmacol. Rev. 2002, 54:527-559.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 527-559
    • Hollinger, S.1    Hepler, J.R.2
  • 6
    • 33747819275 scopus 로고    scopus 로고
    • Effect of exogenous RGS16 gene transfection on growth of glioma cell line C6
    • Hong L., Li Q., Chen G.S., Zhang F., Nie L., Lin S.C. Effect of exogenous RGS16 gene transfection on growth of glioma cell line C6. Ai Zheng 2006, 25:51-55.
    • (2006) Ai Zheng , vol.25 , pp. 51-55
    • Hong, L.1    Li, Q.2    Chen, G.S.3    Zhang, F.4    Nie, L.5    Lin, S.C.6
  • 7
    • 62449130006 scopus 로고    scopus 로고
    • RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway
    • James M.A., Lu Y., Liu Y., Vikis H.G., You M. RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway. Cancer Res. 2009, 69:2108-2116.
    • (2009) Cancer Res. , vol.69 , pp. 2108-2116
    • James, M.A.1    Lu, Y.2    Liu, Y.3    Vikis, H.G.4    You, M.5
  • 8
    • 12844274258 scopus 로고    scopus 로고
    • Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signalling
    • Albig A.R., Schiemann W.P. Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signalling. Mol. Biol. Cell 2005, 16:609-625.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 609-625
    • Albig, A.R.1    Schiemann, W.P.2
  • 9
    • 69249124530 scopus 로고    scopus 로고
    • RGS16 inhibits breast cancer cell growth by mitigating phosphatidylinositol 3-kinase signalling
    • Liang G., Bansal G., Xie Z., Druey K.M. RGS16 inhibits breast cancer cell growth by mitigating phosphatidylinositol 3-kinase signalling. J. Biol. Chem. 2009, 284:21719-21727.
    • (2009) J. Biol. Chem. , vol.284 , pp. 21719-21727
    • Liang, G.1    Bansal, G.2    Xie, Z.3    Druey, K.M.4
  • 10
    • 0037020184 scopus 로고    scopus 로고
    • RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the Gγ subunit-like (GGL) domain of RGS6
    • Liu Z., Chatterjee T.K., Fisher R.A. RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the Gγ subunit-like (GGL) domain of RGS6. J. Biol. Chem. 2002, 277:37832-37839.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37832-37839
    • Liu, Z.1    Chatterjee, T.K.2    Fisher, R.A.3
  • 11
    • 33646362269 scopus 로고    scopus 로고
    • Regulator of G-protein signaling (RGS) proteins differentially control chondrocyte differentiation
    • Appleton C.T., James C.G., Beier F. Regulator of G-protein signaling (RGS) proteins differentially control chondrocyte differentiation. J. Cell. Physiol. 2006, 207:735-745.
    • (2006) J. Cell. Physiol. , vol.207 , pp. 735-745
    • Appleton, C.T.1    James, C.G.2    Beier, F.3
  • 13
    • 34247274512 scopus 로고    scopus 로고
    • Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation
    • Willard M.D., Willard F.S., Li X., Cappell S.D., Snider W.D., Siderovski D.P. Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation. EMBO J. 2007, 26:2029-2040.
    • (2007) EMBO J. , vol.26 , pp. 2029-2040
    • Willard, M.D.1    Willard, F.S.2    Li, X.3    Cappell, S.D.4    Snider, W.D.5    Siderovski, D.P.6
  • 14
    • 34447514412 scopus 로고    scopus 로고
    • i oscillation regulation
    • i oscillation regulation. Gen. Dev. 2007, 21:1803-1816.
    • (2007) Gen. Dev. , vol.21 , pp. 1803-1816
    • Yang, S.1    Li, Y.P.2
  • 19
    • 0032939346 scopus 로고    scopus 로고
    • Protein interactions with the glucose transporter binding protein that provide a link between GLUT1 and the cytoskeleton
    • Bunn R.C., Jensen M.A., Reed B.C. Protein interactions with the glucose transporter binding protein that provide a link between GLUT1 and the cytoskeleton. Mol. Biol. Cell 1999, 10:819-823.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 819-823
    • Bunn, R.C.1    Jensen, M.A.2    Reed, B.C.3
  • 20
    • 0035158872 scopus 로고    scopus 로고
    • GIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways
    • Lou X.H., Yano H., Lee F., Chao M.V., Farquhar M.G. GIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways. Mol. Biol. Cell 2001, 12:615-627.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 615-627
    • Lou, X.H.1    Yano, H.2    Lee, F.3    Chao, M.V.4    Farquhar, M.G.5
  • 22
    • 3242789280 scopus 로고    scopus 로고
    • i-mediated stimulation of c-Jun N-terminal kinase activity
    • i-mediated stimulation of c-Jun N-terminal kinase activity. Br. J. Pharmacol. 2004, 142:635-646.
    • (2004) Br. J. Pharmacol. , vol.142 , pp. 635-646
    • Chan, A.S.L.1    Wong, Y.H.2
  • 23
    • 15744374220 scopus 로고    scopus 로고
    • i/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in PC12 cells and cortical neurons
    • i/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in PC12 cells and cortical neurons. Mol. Pharmacol. 2005, 67:1195-1205.
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1195-1205
    • Wu, E.H.T.1    Wong, Y.H.2
  • 24
    • 14844357948 scopus 로고    scopus 로고
    • i/o proteins are involved in nerve growth factor-induced pro-survival Akt signaling cascade in PC12 cells
    • i/o proteins are involved in nerve growth factor-induced pro-survival Akt signaling cascade in PC12 cells. Cell. Signal. 2005, 17:881-890.
    • (2005) Cell. Signal. , vol.17 , pp. 881-890
    • Wu, E.H.T.1    Wong, Y.H.2
  • 26
    • 34047107246 scopus 로고    scopus 로고
    • An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells
    • Ma H.T., On K.F., Tsang Y.H., Poon R.Y.C. An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells. Nucleic Acids Res. 2007, 35:e22.
    • (2007) Nucleic Acids Res. , vol.35
    • Ma, H.T.1    On, K.F.2    Tsang, Y.H.3    Poon, R.Y.C.4
  • 27
  • 28
    • 18244402890 scopus 로고    scopus 로고
    • Preferences for phosphorylation sites in the Retinoblastoma protein of D-type cyclin-dependent kinases, Cdk4 and Cdk6, in vitro
    • Takaki T., Fukasawa1 K., Suzuki-Takahashi I., Semba K., Kitagawa M., Taya Y., Hirai H. Preferences for phosphorylation sites in the Retinoblastoma protein of D-type cyclin-dependent kinases, Cdk4 and Cdk6, in vitro. J. Biochem. 2005, 137:381-386.
    • (2005) J. Biochem. , vol.137 , pp. 381-386
    • Takaki, T.1    Fukasawa1, K.2    Suzuki-Takahashi, I.3    Semba, K.4    Kitagawa, M.5    Taya, Y.6    Hirai, H.7
  • 29
    • 34547961707 scopus 로고    scopus 로고
    • Tuberin: a stimulus-regulated tumor suppressor protein controlled by a diverse array of receptor tyrosine kinases and G protein-coupled receptors
    • Wu E.H.T., Wu K.K.H., Wong Y.H. Tuberin: a stimulus-regulated tumor suppressor protein controlled by a diverse array of receptor tyrosine kinases and G protein-coupled receptors. Neurosignals 2007, 15:217-227.
    • (2007) Neurosignals , vol.15 , pp. 217-227
    • Wu, E.H.T.1    Wu, K.K.H.2    Wong, Y.H.3
  • 30
    • 0033607633 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Raf by Akt (protein kinase B)
    • Zimmermann S., Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 1999, 286:1741-1744.
    • (1999) Science , vol.286 , pp. 1741-1744
    • Zimmermann, S.1    Moelling, K.2
  • 31
    • 77953708565 scopus 로고    scopus 로고
    • Non-canonical functions of RGS proteins
    • Sethakorn N., Yau D.M., Dulin N.O. Non-canonical functions of RGS proteins. Cell. Signal. 2010, 22:1274-1281.
    • (2010) Cell. Signal. , vol.22 , pp. 1274-1281
    • Sethakorn, N.1    Yau, D.M.2    Dulin, N.O.3
  • 32
    • 70349473057 scopus 로고    scopus 로고
    • Regulator of G-protein signaling (RGS) proteins in cancer biology
    • Hurst J.H., Hooks S.B. Regulator of G-protein signaling (RGS) proteins in cancer biology. Biochem. Pharmacol. 2009, 78:1289-1297.
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 1289-1297
    • Hurst, J.H.1    Hooks, S.B.2
  • 33
    • 58949100016 scopus 로고    scopus 로고
    • Regulator of G-protein signaling expression and function in ovarian cancer cell lines
    • Hurst J.H., Mendpara N., Hooks S.B. Regulator of G-protein signaling expression and function in ovarian cancer cell lines. Cell. Mol. Biol. Lett. 2008, 14:153-174.
    • (2008) Cell. Mol. Biol. Lett. , vol.14 , pp. 153-174
    • Hurst, J.H.1    Mendpara, N.2    Hooks, S.B.3
  • 36
    • 0034672063 scopus 로고    scopus 로고
    • Erk1/2-dependent phosphorylation of Gα-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells
    • Ogier-Denis E., Pattingre S., El Benna J., Codogno P. Erk1/2-dependent phosphorylation of Gα-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells. J. Biol. Chem. 2000, 275:39090-39095.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39090-39095
    • Ogier-Denis, E.1    Pattingre, S.2    El Benna, J.3    Codogno, P.4
  • 37
    • 0035361602 scopus 로고    scopus 로고
    • PTEN induces G1 cell cycle arrest and decreases Cyclin D3 levels in endometrial carcinoma cells
    • Zhu X., Kwon C.H., Schlosshauer P.W., Ellenson L.H., Baker S.J. PTEN induces G1 cell cycle arrest and decreases Cyclin D3 levels in endometrial carcinoma cells. Cancer Res. 2001, 61:4569-4575.
    • (2001) Cancer Res. , vol.61 , pp. 4569-4575
    • Zhu, X.1    Kwon, C.H.2    Schlosshauer, P.W.3    Ellenson, L.H.4    Baker, S.J.5
  • 39
    • 36248985545 scopus 로고    scopus 로고
    • G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis
    • New D.C., Wu K.K.H., Kwok A.W.S., Wong Y.H. G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis. FEBS J. 2007, 274:6025-6036.
    • (2007) FEBS J. , vol.274 , pp. 6025-6036
    • New, D.C.1    Wu, K.K.H.2    Kwok, A.W.S.3    Wong, Y.H.4
  • 40
    • 27844607317 scopus 로고    scopus 로고
    • 4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells
    • 4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells. Cell. Signal. 2006, 18:285-293.
    • (2006) Cell. Signal. , vol.18 , pp. 285-293
    • Wu, E.H.T.1    Wong, Y.H.2
  • 42
    • 34247116441 scopus 로고    scopus 로고
    • Physiological roles of PKB/Akt isoforms in development and disease
    • Dummler B., Hemmings B.A. Physiological roles of PKB/Akt isoforms in development and disease. Biochem. Soc. Trans. 2007, 35:231-235.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 231-235
    • Dummler, B.1    Hemmings, B.A.2
  • 43
    • 33750380920 scopus 로고    scopus 로고
    • Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies
    • Dummler B., Tschopp O., Hynx D., Yang Z.Z., Dirnhofer S., Hemmings B.A. Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies. Mol. Cell. Biol. 2006, 26:8042-8051.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 8042-8051
    • Dummler, B.1    Tschopp, O.2    Hynx, D.3    Yang, Z.Z.4    Dirnhofer, S.5    Hemmings, B.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.