Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo

Breast Cancer Research and Treatment

Volumn 128, Issue 3, 2011, Pages 691-701

  Bluff, J E ^a   Amarzguioui, M ^b   Slattery, J ^a   Reed, M W R ^a   Brown, N J ^a   Staton, C A ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Angiogenesis; Breast cancer; Haemostasis; Tissue factor; VEGF

Indexed keywords

SHORT HAIRPIN RNA; SMALL INTERFERING RNA; THROMBOPLASTIN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CANCER SIZE; CAPILLARY DENSITY; CELL DIFFERENTIATION; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; TREATMENT DURATION; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; UPREGULATION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; RNA, SMALL INTERFERING; THROMBOPLASTIN; TUMOR BURDEN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79960841638     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1149-8     Document Type: Article

References (36)

1. JE Bluff NJ Brown MWR Reed CA Staton 2008 Tissue factor, angiogenesis and tumour progression (review) Breast Cancer Res 10 204 214 18373885 10.1186/bcr1871
2. JE Bluff SR Menakuru SS Cross SE Higham SP Balasubramanian NJ Brown MW Reed CA Staton 2009 Angiogenesis is associated with hyperplasia in human ductal breast disease Br J Cancer 101 666 672 19623180 10.1038/sj.bjc.6605196 1:CAS:528:DC%2BD1MXpvFyisLg%3D
3. CA Staton AS Chetwood IC Cameron SS Cross NJ Brown MWR Reed 2007 The angiogenic switch occurs at the adenoma stage of the adenoma carcinoma sequence in colorectal cancer Gut 56 1426 1432 17566019 10.1136/gut.2007.125286 (Pubitemid 47517839)
4. T Ueno M Toi M Koike S Nakamura T Tominaga 2000 Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration Br J Cancer 83 164 170 10901365 10.1054/bjoc.2000.1272 1:CAS:528:DC%2BD3cXltl2murs%3D (Pubitemid 30411712)
5. CV Ngo K Picha F McCabe, et al. 2007 CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models Int J Cancer 120 1261 1267 17192924 10.1002/ijc.22426 1:CAS:528:DC%2BD2sXhvVOju74%3D
6. M Amarzguioui Q Peng MT Wiiger, et al. 2006 Ex vivo and in vivo delivery of anti-tissue factor siRNA inhibits mouse pulmonary metastasis of B16 melanoma cells Clin Cancer Res 12 4055 4061 16818705 10.1158/1078-0432.CCR-05-2482 1:CAS:528:DC%2BD28XmsValu7c%3D (Pubitemid 44078093)
7. J Rak C Milsom L May P Klement J Yu 2006 Tissue factor in cancer and angiogenesis: the molecular link between genetic tumor progression, tumour neovascularization, and cancer coagulopathy Semin Thromb Hemost 32 54 70 16479463 10.1055/s-2006-933341 1:CAS:528:DC%2BD28XisFajs78%3D
8. K Abe M Shoji J Chen, et al. 1999 Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor Proc Natl Acad Sci USA 96 8663 8668 10411932 10.1073/pnas.96.15.8663 1:CAS:528:DyaK1MXkslOktL0%3D (Pubitemid 29354848)
9. E Krajewska CE Lewis S Tazzyman Y-Y Chen CA Staton 2010 A novel fragment derived from the beta chain of human fibrinogen, β43-63, is a potent inhibitor of activated endothelial cells in vitro and in vivo Br J Cancer 102 594 601 20068569 10.1038/sj.bjc.6605495 1:CAS:528:DC%2BC3cXhsVSrsL4%3D
10. L Aagaard M Amarzguioui G Sun, et al. 2007 A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha Mol Ther 15 938 945 17311008 1:CAS:528:DC%2BD2sXhtVejt7bO (Pubitemid 46621652)
11. X Wang M Wang M Amarzguioui F Liu ∅ Fodstad H Prydz 2004 Down-regulation of tissue factor by RNA interference in human melanoma LOX-L cells reduce pulmonary metastasis in nude mice Int J Cancer 112 994 1002 15386437 10.1002/ijc.20527 1:CAS:528:DC%2BD2cXhtVSnsLnO (Pubitemid 39507005)
12. S Filleur A Courtin S Ait-Si-Ali, et al. 2003 SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth Cancer Res 63 3919 3922 12873985 1:CAS:528:DC%2BD3sXlsFOjtbs%3D (Pubitemid 36917906)
13. X Lin Y Yu H Zhao Y Zhang J Manela DA Tonetti 2006 Overexpresion of PKCα is required to impart estradiol inhibition and tamoxifen-resistance in a T47D human breast cancer tumour model Carcinogenesis 27 1538 1546 16513679 10.1093/carcin/bgl002 1:CAS:528:DC%2BD28XosVemurs%3D (Pubitemid 44288042)
14. CA Staton SM Stribbling C Garcia-Echeverria JP Bury S Tazzyman CE Lewis NJ Brown 2007 Identification of key residues involved in mediating the in vivo anti-tumour/anti-endothelial activity of Alphastatin J Thromb Haemost 5 846 854 17408413 10.1111/j.1538-7836.2007.02432.x 1:CAS:528:DC%2BD2sXltlWgtLY%3D (Pubitemid 46563586)
15. GM Tozer ZM Bhujwalla JR Griffiths RJ Maxwell 1989 Phosphorus-31 magnetic resonance spectroscopy and blood perfusion of the RIF-1 tumor following X-irradiation Int J Radiat Oncol Biol Phys 16 155 164 2912937 10.1016/0360-3016(89)90023-0 1:CAS:528:DyaL1MXhtlWntLs%3D (Pubitemid 19045348)
16. CA Staton NJ Brown GR Rodgers KP Corke S Tazzyman JCE Underwood CE Lewis 2004 Alphastatin, a 24 amino-acid fragment of human fibrinogen, is a potent new inhibitor of activated endothelial cells in vitro and in vivo Blood 103 601 606 14512300 10.1182/blood-2003-07-2192 1:CAS:528:DC%2BD2cXmsFCiuw%3D%3D (Pubitemid 38140093)
17. FB Morrone DL Oliveira P Gamermann, et al. 2006 In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model BMC Cancer 6 226 16995949 10.1186/1471-2407-6-226 (Pubitemid 44541832)
18. N Ferrara HP Gerber J LeCouter 2003 The biology of VEGF and its receptors Nat Med 9 669 676 12778165 10.1038/nm0603-669 1:CAS:528:DC%2BD3sXktFOnur4%3D (Pubitemid 36749215)
19. Y He G Chang S Zhan X Song X Wang Y Luo 2008 Soluble tissue factor has unique angiogenic activities that selectively promote migration and differentiation but not proliferation of endothelial cells Biochem Biophys Res Commun 370 489 494 18395519 10.1016/j.bbrc.2008.03.133 1:CAS:528: DC%2BD1cXlsFOht7Y%3D
20. JE Hobbs A Zakarija DL Cundiff, et al. 2007 Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model Thromb Res 120 S13 S21 18023707 10.1016/S0049-3848(07)70126-3 (Pubitemid 350101769)
21. A Amirkhosravi T Meyer G Warnes, et al. 1998 Pentoxifylline inhibits hypoxia-induced upregulation of tumor cell tissue factor and vascular endothelial growth factor Thromb Haemost 80 598 602 9798977 1:CAS:528: DyaK1cXms1ahs70%3D (Pubitemid 28479346)
22. M Sawada S Miyake S Ohdama, et al. 1999 Expression of tissue factor in non-small-cell lung cancers and its relationship to metastasis Br J Cancer 79 472 477 10027315 10.1038/sj.bjc.6690073 1:CAS:528:DyaK1MXhtlejtro%3D (Pubitemid 29046221)
23. H Kataoka H Uchino Y Asada, et al. 1997 Analysis of tissue factor and tissue factor pathway inhibitor expression in human colorectal carcinoma cell lines and metastatic sublines to the liver Int J Cancer 72 878 884 9311608 10.1002/(SICI)1097-0215(19970904)72:5<878::AID-IJC27>3.0.CO;2-3 1:CAS:528:DyaK2sXmtVKqsr4%3D (Pubitemid 27431534)
24. BM Mueller RA Reisfeld TS Edgington W Ruf 1992 Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis Proc Natl Acad Sci USA 89 11832 11836 1465406 10.1073/pnas.89.24.11832 1:CAS:528:DyaK3sXpvFamtg%3D%3D (Pubitemid 23004738)
25. G Matsumoto T Kushibiki Y Kinoshita, et al. 2006 Cationized gelatin delivery of a plasmid DNA expressing small interference RNA for VEGF inhibits murine squamous cell carcinoma Cancer Sci 97 313 321 16630124 10.1111/j.1349-7006.2006.00174.x 1:CAS:528:DC%2BD28XksVWksbk%3D
26. J Tao YT Tu CZ Huang, et al. 2005 Inhibiting the growth of malignant melanoma by blocking the expression of vascular endothelial growth factor using an RNA interference approach Br J Dermatol 153 715 724 16181451 10.1111/j.1365-2133.2005.06765.x 1:CAS:528:DC%2BD2MXhtFyhu7%2FJ (Pubitemid 41415896)
27. JL Yu L May V Lhotak, et al. 2005 Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis Blood 105 1734 1741 15494427 10.1182/blood-2004-05-2042 1:CAS:528:DC%2BD2MXhsVCqu74%3D (Pubitemid 40223697)
28. H Uusitalo-Jarvinen T Kurokawa BM Mueller, et al. 2007 Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis Arterioscler Thromb Vasc Biol 27 1456 1462 17363687 10.1161/ATVBAHA.107.142539 1:CAS:528:DC%2BD2sXltl2itL0%3D (Pubitemid 46809438)
29. HH Versteeg F Schaffner M Kerver, et al. 2008 Inhibition of tissue factor signaling suppresses tumor growth Blood 111 190 199 17901245 10.1182/blood-2007-07-101048 1:CAS:528:DC%2BD1cXjtVKjug%3D%3D
30. DR Morris Y Ding TK Ricks A Gullapalli BL Wolfe J Trejo 2006 Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells Cancer Res 66 307 314 16397244 10.1158/0008-5472.CAN-05-1735 1:CAS:528:DC%2BD28XhsFWnsA%3D%3D (Pubitemid 43166037)
31. Y Zhang Y Deng T Luther, et al. 1994 Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice J Clin Invest 94 1320 1327 7521887 10.1172/JCI117451 1:CAS:528:DyaK2cXlslKnsbc%3D (Pubitemid 24286478)
32. F Geler V Voss S Dutzmann R Gerlach D Kogel 2010 Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells Neuroscience 165 1312 1322 10.1016/j.neuroscience.2009.11.049
33. DA Morrow SA Murphy CH McCabe N Mackman HC Wong EM Antman 2005 Potent inhibition of thrombin with a monoclonal antibody against tissue factor (Sunol-cH36): results of the PROXIMATE-TIMI 27 trial Eur Heart J 26 682 688 15684280 10.1093/eurheartj/ehi094 1:CAS:528:DC%2BD2MXksFGnsrY%3D (Pubitemid 40516880)
34. SH Kim JH Jeong SH Lee SW Kim TG Park 2008 Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer J Control Release 129 107 116 18486981 10.1016/j.jconrel.2008.03.008 1:CAS:528:DC%2BD1cXnsFaltbo%3D
35. P Mu S Nagahara N Makita Y Tarumi K Kadomatsu Y Takei 2009 Systemic delivery of siRNA specific to tumor mediated by atelocollagen: combined therapy using siRNA targeting Bcl-xL and cisplatin against prostate cancer Int J Cancer 125 2978 2990 19422046 10.1002/ijc.24382 1:CAS:528:DC%2BD1MXhtlSqsLrL
36. N Yagi I Manabe T Tottori, et al. 2009 A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo Cancer Res 69 6531 6538 19654315 10.1158/0008-5472.CAN-08-3945 1:CAS:528: DC%2BD1MXpvFejtro%3D