메뉴 건너뛰기




Volumn 317, Issue 15, 2011, Pages 2086-2098

Inhibition of glycogen synthase kinase-3 enhances the differentiation and reduces the proliferation of adult human olfactory epithelium neural precursors

Author keywords

Differentiation; GSK 3; Olfactory mucosa; Stem cell; TAT(47 57)

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3;

EID: 79960835809     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2011.06.004     Document Type: Article
Times cited : (16)

References (64)
  • 1
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds B.A., Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992, 255:1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 3
    • 0002436390 scopus 로고
    • The olfactory system: a model for the study of neurogenesis and axon regeneration in mammals
    • Raven Press, New York, C.W. Cotman (Ed.)
    • Graziadei P.P.C., Monti Graziadei G.A. The olfactory system: a model for the study of neurogenesis and axon regeneration in mammals. Neuronal Plasticity 1978, 131-153. Raven Press, New York. C.W. Cotman (Ed.).
    • (1978) Neuronal Plasticity , pp. 131-153
    • Graziadei, P.P.C.1    Monti Graziadei, G.A.2
  • 4
    • 0026048481 scopus 로고
    • Cell dynamics in the adult mouse olfactory epithelium: a quantitative autoradiographic study
    • Mackay-Sim A., Kittel P. Cell dynamics in the adult mouse olfactory epithelium: a quantitative autoradiographic study. J. Neurosci. 1991, 11:979-984.
    • (1991) J. Neurosci. , vol.11 , pp. 979-984
    • Mackay-Sim, A.1    Kittel, P.2
  • 5
    • 0031927946 scopus 로고    scopus 로고
    • The neuronal stem cell of the olfactory epithelium
    • Calof A.L., Mumm J.S., Rim P.C., Shou J. The neuronal stem cell of the olfactory epithelium. J. Neurobiol. 1998, 36:190-205.
    • (1998) J. Neurobiol. , vol.36 , pp. 190-205
    • Calof, A.L.1    Mumm, J.S.2    Rim, P.C.3    Shou, J.4
  • 9
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein P.S., Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl Acad. Sci. U. S. A. 1996, 93:8455-8459.
    • (1996) Proc. Natl Acad. Sci. U. S. A. , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 10
    • 33750866196 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions
    • Jope R.S., Roh M.S. Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Curr. Drug Targets 2006, 7:1421-1434.
    • (2006) Curr. Drug Targets , vol.7 , pp. 1421-1434
    • Jope, R.S.1    Roh, M.S.2
  • 11
    • 13444269371 scopus 로고    scopus 로고
    • Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta -50T/C SNP
    • Benedetti F., Serretti A., Pontiggia A., Bernasconi A., Lorenzi C., Colombo C., Smeraldi E. Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta -50T/C SNP. Neurosci. Lett. 2005, 376:51-55.
    • (2005) Neurosci. Lett. , vol.376 , pp. 51-55
    • Benedetti, F.1    Serretti, A.2    Pontiggia, A.3    Bernasconi, A.4    Lorenzi, C.5    Colombo, C.6    Smeraldi, E.7
  • 13
    • 20544437694 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs
    • Gould T.D., Manji H.K. Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology 2005, 30:1223-1237.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1223-1237
    • Gould, T.D.1    Manji, H.K.2
  • 16
    • 0033625098 scopus 로고    scopus 로고
    • Low GSK-3beta immunoreactivity in postmortem frontal cortex of schizophrenic patients
    • Kozlovsky N., Belmaker R.H., Agam G. Low GSK-3beta immunoreactivity in postmortem frontal cortex of schizophrenic patients. Am. J. Psychiatry 2000, 157:831-833.
    • (2000) Am. J. Psychiatry , vol.157 , pp. 831-833
    • Kozlovsky, N.1    Belmaker, R.H.2    Agam, G.3
  • 17
    • 0035476357 scopus 로고    scopus 로고
    • Low GSK-3 activity in frontal cortex of schizophrenic patients
    • Kozlovsky N., Belmaker R.H., Agam G. Low GSK-3 activity in frontal cortex of schizophrenic patients. Schizophr. Res. 2001, 52:101-105.
    • (2001) Schizophr. Res. , vol.52 , pp. 101-105
    • Kozlovsky, N.1    Belmaker, R.H.2    Agam, G.3
  • 20
    • 0037392942 scopus 로고    scopus 로고
    • The specificities of protein kinase inhibitors: an update
    • Bain J., McLauchlan H., Elliott M., Cohen P. The specificities of protein kinase inhibitors: an update. Biochem. J. 2003, 371:199-204.
    • (2003) Biochem. J. , vol.371 , pp. 199-204
    • Bain, J.1    McLauchlan, H.2    Elliott, M.3    Cohen, P.4
  • 21
    • 77955860888 scopus 로고    scopus 로고
    • Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction
    • Allsopp T.E., Bunnage M.E., Fish P.V. Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction. Med. Chem. Commun. 2010, 1:16-29.
    • (2010) Med. Chem. Commun. , vol.1 , pp. 16-29
    • Allsopp, T.E.1    Bunnage, M.E.2    Fish, P.V.3
  • 22
    • 61649121919 scopus 로고    scopus 로고
    • Selective enhancement of the uptake and bioactivity of a TAT-conjugated peptide inhibitor of glycogen synthase kinase-3
    • Manceur A.P., Driscoll B.D., Sun W., Audet J. Selective enhancement of the uptake and bioactivity of a TAT-conjugated peptide inhibitor of glycogen synthase kinase-3. Mol. Ther. 2009, 17:500-507.
    • (2009) Mol. Ther. , vol.17 , pp. 500-507
    • Manceur, A.P.1    Driscoll, B.D.2    Sun, W.3    Audet, J.4
  • 24
    • 58549109668 scopus 로고    scopus 로고
    • Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides
    • Bone H.K., Damiano T., Bartlett S., Perry A., Letchford J., Ripoll Y.S., Nelson A.S., Welham M.J. Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides. Chem. Biol. 2009, 16:15-27.
    • (2009) Chem. Biol. , vol.16 , pp. 15-27
    • Bone, H.K.1    Damiano, T.2    Bartlett, S.3    Perry, A.4    Letchford, J.5    Ripoll, Y.S.6    Nelson, A.S.7    Welham, M.J.8
  • 25
    • 4344619713 scopus 로고    scopus 로고
    • Pharmacological inhibitors of glycogen synthase kinase 3
    • Meijer L., Flajolet M., Greengard P. Pharmacological inhibitors of glycogen synthase kinase 3. Trends Pharmacol. Sci. 2004, 25:471-480.
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 471-480
    • Meijer, L.1    Flajolet, M.2    Greengard, P.3
  • 27
    • 33845302976 scopus 로고    scopus 로고
    • Peptides targeting protein kinases: strategies and implications
    • Kaidanovich-Beilin O., Eldar-Finkelman H. Peptides targeting protein kinases: strategies and implications. Physiology (Bethesda) 2006, 21:411-418.
    • (2006) Physiology (Bethesda) , vol.21 , pp. 411-418
    • Kaidanovich-Beilin, O.1    Eldar-Finkelman, H.2
  • 28
    • 0031034809 scopus 로고    scopus 로고
    • Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts
    • Welsh G.I., Patel J.C., Proud C.G. Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Anal. Biochem. 1997, 244:16-21.
    • (1997) Anal. Biochem. , vol.244 , pp. 16-21
    • Welsh, G.I.1    Patel, J.C.2    Proud, C.G.3
  • 30
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N., Meijer L., Skaltsounis L., Greengard P., Brivanlou A.H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 2004, 10:55-63.
    • (2004) Nat. Med. , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 31
    • 34249311572 scopus 로고    scopus 로고
    • Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
    • Doble B.W., Patel S., Wood G.A., Kockeritz L.K., Woodgett J.R. Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev. Cell 2007, 12:957-971.
    • (2007) Dev. Cell , vol.12 , pp. 957-971
    • Doble, B.W.1    Patel, S.2    Wood, G.A.3    Kockeritz, L.K.4    Woodgett, J.R.5
  • 32
    • 27144526161 scopus 로고    scopus 로고
    • Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation
    • Fok E.Y., Zandstra P.W. Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation. Stem Cells 2005, 23:1333-1342.
    • (2005) Stem Cells , vol.23 , pp. 1333-1342
    • Fok, E.Y.1    Zandstra, P.W.2
  • 33
    • 33344472348 scopus 로고    scopus 로고
    • Cell cycle alterations in biopsied olfactory neuroepithelium in schizophrenia and bipolar I disorder using cell culture and gene expression analyses
    • McCurdy R.D., Feron F., Perry C., Chant D.C., McLean D., Matigian N., Hayward N.K., McGrath J.J., Mackay-Sim A. Cell cycle alterations in biopsied olfactory neuroepithelium in schizophrenia and bipolar I disorder using cell culture and gene expression analyses. Schizophr. Res. 2006, 82:163-173.
    • (2006) Schizophr. Res. , vol.82 , pp. 163-173
    • McCurdy, R.D.1    Feron, F.2    Perry, C.3    Chant, D.C.4    McLean, D.5    Matigian, N.6    Hayward, N.K.7    McGrath, J.J.8    Mackay-Sim, A.9
  • 34
    • 79960838906 scopus 로고    scopus 로고
    • Applying an olfactory neuroepithelial model of neurodevelopment to familial schizophrenia
    • McCurdy R., Witterick I., Lin D., Weksberg R., Chow E., Bassett A. Applying an olfactory neuroepithelial model of neurodevelopment to familial schizophrenia. Schizophr. Bull. 2007, 33:301.
    • (2007) Schizophr. Bull. , vol.33 , pp. 301
    • McCurdy, R.1    Witterick, I.2    Lin, D.3    Weksberg, R.4    Chow, E.5    Bassett, A.6
  • 35
    • 1542617770 scopus 로고    scopus 로고
    • Adult human olfactory neural progenitors cultured in defined medium
    • Zhang X., Klueber K.M., Guo Z., Lu C., Roisen F.J. Adult human olfactory neural progenitors cultured in defined medium. Exp. Neurol. 2004, 186:112-123.
    • (2004) Exp. Neurol. , vol.186 , pp. 112-123
    • Zhang, X.1    Klueber, K.M.2    Guo, Z.3    Lu, C.4    Roisen, F.J.5
  • 38
    • 67649818853 scopus 로고    scopus 로고
    • Olfactory stem cells can be induced to express chondrogenic phenotype in a rat intervertebral disc injury model
    • Murrell W., Sanford E., Anderberg L., Cavanagh B., Mackay-Sim A. Olfactory stem cells can be induced to express chondrogenic phenotype in a rat intervertebral disc injury model. Spine J. 2009, 9:585-594.
    • (2009) Spine J. , vol.9 , pp. 585-594
    • Murrell, W.1    Sanford, E.2    Anderberg, L.3    Cavanagh, B.4    Mackay-Sim, A.5
  • 39
    • 0032212348 scopus 로고    scopus 로고
    • An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts
    • Ryves W.J., Fryer L., Dale T., Harwood A.J. An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts. Anal. Biochem. 1998, 264:124-127.
    • (1998) Anal. Biochem. , vol.264 , pp. 124-127
    • Ryves, W.J.1    Fryer, L.2    Dale, T.3    Harwood, A.J.4
  • 41
    • 33947688612 scopus 로고    scopus 로고
    • Flow cytometric screening of cell-penetrating peptides for their uptake into embryonic and adult stem cells
    • Manceur A., Wu A., Audet J. Flow cytometric screening of cell-penetrating peptides for their uptake into embryonic and adult stem cells. Anal. Biochem. 2007, 364:51-59.
    • (2007) Anal. Biochem. , vol.364 , pp. 51-59
    • Manceur, A.1    Wu, A.2    Audet, J.3
  • 42
    • 77954874401 scopus 로고    scopus 로고
    • GSK3 signalling in neural development. Nature reviews
    • Hur E.M., Zhou F.Q. GSK3 signalling in neural development. Nature reviews. Neuroscience 2010, 11:539-551.
    • (2010) Neuroscience , vol.11 , pp. 539-551
    • Hur, E.M.1    Zhou, F.Q.2
  • 43
    • 30044444251 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation
    • Trowbridge J.J., Xenocostas A., Moon R.T., Bhatia M. Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat. Med. 2006, 12:89-98.
    • (2006) Nat. Med. , vol.12 , pp. 89-98
    • Trowbridge, J.J.1    Xenocostas, A.2    Moon, R.T.3    Bhatia, M.4
  • 44
    • 33645511274 scopus 로고    scopus 로고
    • Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin
    • Inoue T., Kagawa T., Fukushima M., Shimizu T., Yoshinaga Y., Takada S., Tanihara H., Taga T. Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin. Stem Cells 2006, 24:95-104.
    • (2006) Stem Cells , vol.24 , pp. 95-104
    • Inoue, T.1    Kagawa, T.2    Fukushima, M.3    Shimizu, T.4    Yoshinaga, Y.5    Takada, S.6    Tanihara, H.7    Taga, T.8
  • 45
    • 59649100796 scopus 로고    scopus 로고
    • Wnt signaling controls the fate of mesenchymal stem cells
    • Ling L., Nurcombe V., Cool S.M. Wnt signaling controls the fate of mesenchymal stem cells. Gene 2009, 433:1-7.
    • (2009) Gene , vol.433 , pp. 1-7
    • Ling, L.1    Nurcombe, V.2    Cool, S.M.3
  • 48
    • 73349121619 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells
    • Cajanek L., Ribeiro D., Liste I., Parish C.L., Bryja V., Arenas E. Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells. Stem Cells 2009, 27:2917-2927.
    • (2009) Stem Cells , vol.27 , pp. 2917-2927
    • Cajanek, L.1    Ribeiro, D.2    Liste, I.3    Parish, C.L.4    Bryja, V.5    Arenas, E.6
  • 49
    • 35448972941 scopus 로고    scopus 로고
    • Wnt3a regulates survival, expansion, and maintenance of neural progenitors derived from human embryonic stem cells
    • Davidson K.C., Jamshidi P., Daly R., Hearn M.T., Pera M.F., Dottori M. Wnt3a regulates survival, expansion, and maintenance of neural progenitors derived from human embryonic stem cells. Mol. Cell. Neurosci. 2007, 36:408-415.
    • (2007) Mol. Cell. Neurosci. , vol.36 , pp. 408-415
    • Davidson, K.C.1    Jamshidi, P.2    Daly, R.3    Hearn, M.T.4    Pera, M.F.5    Dottori, M.6
  • 50
    • 44849086769 scopus 로고    scopus 로고
    • A unique cell population in the mouse olfactory bulb displays nuclear beta-catenin signaling during development and olfactory sensory neuron regeneration
    • Booker-Dwyer T., Hirsh S., Zhao H. A unique cell population in the mouse olfactory bulb displays nuclear beta-catenin signaling during development and olfactory sensory neuron regeneration. Dev. Neurobiol. 2008, 68:859-869.
    • (2008) Dev. Neurobiol. , vol.68 , pp. 859-869
    • Booker-Dwyer, T.1    Hirsh, S.2    Zhao, H.3
  • 52
    • 3242889925 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells
    • Hirabayashi Y., Itoh Y., Tabata H., Nakajima K., Akiyama T., Masuyama N., Gotoh Y. The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 2004, 131:2791-2801.
    • (2004) Development , vol.131 , pp. 2791-2801
    • Hirabayashi, Y.1    Itoh, Y.2    Tabata, H.3    Nakajima, K.4    Akiyama, T.5    Masuyama, N.6    Gotoh, Y.7
  • 53
    • 77950512319 scopus 로고    scopus 로고
    • Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex
    • Kuwahara A., Hirabayashi Y., Knoepfler P.S., Taketo M.M., Sakai J., Kodama T., Gotoh Y. Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development 2010, 137:1035-1044.
    • (2010) Development , vol.137 , pp. 1035-1044
    • Kuwahara, A.1    Hirabayashi, Y.2    Knoepfler, P.S.3    Taketo, M.M.4    Sakai, J.5    Kodama, T.6    Gotoh, Y.7
  • 54
    • 12344307661 scopus 로고    scopus 로고
    • GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons
    • Castelo-Branco G., Rawal N., Arenas E. GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. J. Cell Sci. 2004, 117:5731-5737.
    • (2004) J. Cell Sci. , vol.117 , pp. 5731-5737
    • Castelo-Branco, G.1    Rawal, N.2    Arenas, E.3
  • 55
    • 57349182470 scopus 로고    scopus 로고
    • Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells
    • Shimizu T., Kagawa T., Inoue T., Nonaka A., Takada S., Aburatani H., Taga T. Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. Mol. Cell. Biol. 2008, 28:7427-7441.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 7427-7441
    • Shimizu, T.1    Kagawa, T.2    Inoue, T.3    Nonaka, A.4    Takada, S.5    Aburatani, H.6    Taga, T.7
  • 56
    • 0037135177 scopus 로고    scopus 로고
    • Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
    • Chenn A., Walsh C.A. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 2002, 297:365-369.
    • (2002) Science , vol.297 , pp. 365-369
    • Chenn, A.1    Walsh, C.A.2
  • 57
    • 0036333208 scopus 로고    scopus 로고
    • A mitogen gradient of dorsal midline Wnts organizes growth in the CNS
    • Megason S.G., McMahon A.P. A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development 2002, 129:2087-2098.
    • (2002) Development , vol.129 , pp. 2087-2098
    • Megason, S.G.1    McMahon, A.P.2
  • 58
    • 0038383629 scopus 로고    scopus 로고
    • Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2
    • Viti J., Gulacsi A., Lillien L. Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2. J. Neurosci. 2003, 23:5919-5927.
    • (2003) J. Neurosci. , vol.23 , pp. 5919-5927
    • Viti, J.1    Gulacsi, A.2    Lillien, L.3
  • 59
    • 77953040859 scopus 로고    scopus 로고
    • A cross-disciplinary approach to understanding neural stem cells in development and disease
    • Henrique D., Bally-Cuif L. A cross-disciplinary approach to understanding neural stem cells in development and disease. Development 2010, 137:1933-1938.
    • (2010) Development , vol.137 , pp. 1933-1938
    • Henrique, D.1    Bally-Cuif, L.2
  • 60
    • 0344994580 scopus 로고    scopus 로고
    • Dopamine promotes differentiation of olfactory neuron in vitro
    • Feron F., Vincent A., Mackay-Sim A. Dopamine promotes differentiation of olfactory neuron in vitro. Brain Res. 1999, 845:252-259.
    • (1999) Brain Res. , vol.845 , pp. 252-259
    • Feron, F.1    Vincent, A.2    Mackay-Sim, A.3
  • 61
    • 26944455557 scopus 로고    scopus 로고
    • Regulation of adult olfactory neurogenesis by insulin-like growth factor-I
    • McCurdy R.D., Feron F., McGrath J.J., Mackay-Sim A. Regulation of adult olfactory neurogenesis by insulin-like growth factor-I. Eur. J. Neurosci. 2005, 22:1581-1588.
    • (2005) Eur. J. Neurosci. , vol.22 , pp. 1581-1588
    • McCurdy, R.D.1    Feron, F.2    McGrath, J.J.3    Mackay-Sim, A.4
  • 63
    • 33645016905 scopus 로고    scopus 로고
    • Induction of neuronal differentiation of adult human olfactory neuroepithelial-derived progenitors
    • Zhang X., Klueber K.M., Guo Z., Cai J., Lu C., Winstead W.I., Qiu M., Roisen F.J. Induction of neuronal differentiation of adult human olfactory neuroepithelial-derived progenitors. Brain Res. 2006, 1073-1074:109-119.
    • (2006) Brain Res. , pp. 109-119
    • Zhang, X.1    Klueber, K.M.2    Guo, Z.3    Cai, J.4    Lu, C.5    Winstead, W.I.6    Qiu, M.7    Roisen, F.J.8
  • 64
    • 0035910366 scopus 로고    scopus 로고
    • Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats
    • Lu J., Feron F., Ho S.M., Mackay-Sim A., Waite P.M. Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats. Brain Res. 2001, 889:344-357.
    • (2001) Brain Res. , vol.889 , pp. 344-357
    • Lu, J.1    Feron, F.2    Ho, S.M.3    Mackay-Sim, A.4    Waite, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.