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Volumn 1, Issue , 2011, Pages

Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins

Author keywords

Bipolar disorder; DNA methylation; Monozygotic twins; Serotonin transporter

Indexed keywords

SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

EID: 79960828534     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2011.26     Document Type: Article
Times cited : (81)

References (51)
  • 3
    • 34748836926 scopus 로고    scopus 로고
    • 11C]DASB; Comparison with Bipolar Disorder
    • DOI 10.1016/j.biopsych.2007.03.016, PII S0006322307002363, Bipolar Disorder and OCD: Circuitry of Impulsive and Compulsive Behaviors
    • Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS et al. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. Biol Psychiatry 2007; 62: 870-877. (Pubitemid 47488222)
    • (2007) Biological Psychiatry , vol.62 , Issue.8 , pp. 870-877
    • Cannon, D.M.1    Ichise, M.2    Rollis, D.3    Klaver, J.M.4    Gandhi, S.K.5    Charney, D.S.6    Manji, H.K.7    Drevets, W.C.8
  • 4
    • 77953939676 scopus 로고    scopus 로고
    • Decreased brain serotonin transporter binding in the euthymic state of bipolar I but not bipolar II disorder: A SPECT study
    • Chou YH, Wang SJ, Lin CL, Mao WC, Lee SM, Liao MH. Decreased brain serotonin transporter binding in the euthymic state of bipolar I but not bipolar II disorder: A SPECT study. Bipolar Disord 2010; 12: 312-318.
    • (2010) Bipolar Disord , vol.12 , pp. 312-318
    • Chou, Y.H.1    Wang, S.J.2    Lin, C.L.3    Mao, W.C.4    Lee, S.M.5    Liao, M.H.6
  • 11
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: A replication
    • DOI 10.1001/archpsyc.62.5.529
    • Kendler KS, Kuhn JW, Vittum J, Prescott CA, Riley B. The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: A replication. Arch Gen Psychiatry 2005; 62: 529-535. (Pubitemid 40628882)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.5 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 12
    • 32144435933 scopus 로고    scopus 로고
    • Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder
    • DOI 10.1016/j.biopsych.2005.07.014, PII S000632230500867X
    • Surtees PG, Wainwright NW, Willis-Owen SA, Luben R, Day NE, Flint J. Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder. Biol Psychiatry 2006; 59: 224-229. (Pubitemid 43208968)
    • (2006) Biological Psychiatry , vol.59 , Issue.3 , pp. 224-229
    • Surtees, P.G.1    Wainwright, N.W.J.2    Willis-Owen, S.A.G.3    Luben, R.4    Day, N.E.5    Flint, J.6
  • 13
    • 38349150151 scopus 로고    scopus 로고
    • The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: Review and methodological analysis
    • Uher R, McGuffin P. The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: Review and methodological analysis. Mol Psychiatry 2008; 13: 131-146.
    • (2008) Mol Psychiatry , vol.13 , pp. 131-146
    • Uher, R.1    McGuffin, P.2
  • 14
    • 77951854270 scopus 로고    scopus 로고
    • Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
    • Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010; 167: 509-527.
    • (2010) Am J Psychiatry , vol.167 , pp. 509-527
    • Caspi, A.1    Hariri, A.R.2    Holmes, A.3    Uher, R.4    Moffitt, T.E.5
  • 16
    • 40849116456 scopus 로고    scopus 로고
    • Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins
    • DOI 10.1038/sj.mp.4002001, PII 4002001
    • Kuratomi G, Iwamoto K, Bundo M, Kusumi I, Kato N, Iwata N et al. Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Mol Psychiatry 2008; 13: 429-441. (Pubitemid 351399814)
    • (2008) Molecular Psychiatry , vol.13 , Issue.4 , pp. 429-441
    • Kuratomi, G.1    Iwamoto, K.2    Bundo, M.3    Kusumi, I.4    Kato, N.5    Iwata, N.6    Ozaki, N.7    Kato, T.8
  • 20
    • 33745039815 scopus 로고    scopus 로고
    • Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene
    • DOI 10.1002/ajmg.b.30316
    • Mill J, Dempster E, Caspi A, Williams B, Moffitt T, Craig I. Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. Am J Med Genet B Neuropsychiatr Genet 2006; 141B: 421-425. (Pubitemid 43872897)
    • (2006) American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics , vol.141 , Issue.4 , pp. 421-425
    • Mill, J.1    Dempster, E.2    Caspi, A.3    Williams, B.4    Moffitt, T.5    Craig, I.6
  • 27
    • 40849109768 scopus 로고    scopus 로고
    • Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
    • Bruder CE, Piotrowski A, Gijsbers AA, Andersson R, Erickson S, Diaz de Stahl T et al. Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am J Hum Genet 2008; 82: 763-771.
    • (2008) Am J Hum Genet , vol.82 , pp. 763-771
    • Bruder, C.E.1    Piotrowski, A.2    Gijsbers, A.A.3    Andersson, R.4    Erickson, S.5    Diaz De Stahl, T.6
  • 28
    • 0028931306 scopus 로고
    • Chronobiological approach for treatment-resistant rapid cycling affective disorders
    • Kusumi I, Ohmori T, Kohsaka M, Ito M, Honma H, Koyama T. Chronobiological approach for treatment-resistant rapid cycling affective disorders. Biol Psychiatry 1995; 37: 553-559.
    • (1995) Biol Psychiatry , vol.37 , pp. 553-559
    • Kusumi, I.1    Ohmori, T.2    Kohsaka, M.3    Ito, M.4    Honma, H.5    Koyama, T.6
  • 29
    • 79954499505 scopus 로고    scopus 로고
    • Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines
    • Sugawara H, Iwamoto K, Bundo M, Ueda J, Ishigooka J, Kato T. Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines. Epigenetics 2011; 6: 508-515.
    • (2011) Epigenetics , vol.6 , pp. 508-515
    • Sugawara, H.1    Iwamoto, K.2    Bundo, M.3    Ueda, J.4    Ishigooka, J.5    Kato, T.6
  • 30
    • 61949186636 scopus 로고    scopus 로고
    • Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder
    • Hayashi A, Kasahara T, Kametani M, Toyota T, Yoshikawa T, Kato T. Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder. Int J Neuropsychopharmacol 2009; 12: 33-43.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 33-43
    • Hayashi, A.1    Kasahara, T.2    Kametani, M.3    Toyota, T.4    Yoshikawa, T.5    Kato, T.6
  • 33
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: Designing primers for methylation PCRs
    • Li LC, Dahiya R. MethPrimer: Designing primers for methylation PCRs. Bioinformatics 2002; 18: 1427-1431. (Pubitemid 35414532)
    • (2002) Bioinformatics , vol.18 , Issue.11 , pp. 1427-1431
    • Li, L.-C.1    Dahiya, R.2
  • 34
    • 48449097251 scopus 로고    scopus 로고
    • QUMA: Quantification tool for methylation analysis
    • Kumaki Y, Oda M, Okano M. QUMA: Quantification tool for methylation analysis. Nucleic Acids Res 2008; 36: W170-W175.
    • (2008) Nucleic Acids Res , vol.36
    • Kumaki, Y.1    Oda, M.2    Okano, M.3
  • 35
    • 0038678777 scopus 로고    scopus 로고
    • Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites
    • Colella S, Shen L, Baggerly KA, Issa JP, Krahe R. Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. Biotechniques 2003; 35: 146-150. (Pubitemid 36828724)
    • (2003) BioTechniques , vol.35 , Issue.1 , pp. 146-150
    • Colella, S.1    Shen, L.2    Baggerly, K.A.3    Issa, J.-P.J.4    Krahe, R.5
  • 36
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Taubman J, Greenberg BD et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 2006; 78: 815-826.
    • (2006) Am J Hum Genet , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3    Akhtar, L.A.4    Taubman, J.5    Greenberg, B.D.6
  • 38
    • 0035118875 scopus 로고    scopus 로고
    • Serotonin transporter polymorphisms: No association with response to antipsychotic treatment, but associations with the schizoparanoid and subtypes of schizophrenia
    • DOI 10.1038/sj.mp.4000821
    • Kaiser R, Tremblay PB, Schmider J, Henneken M, Dettling M, Muller-Oerlinghausen B et al. Serotonin transporter polymorphisms: No association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia. Mol Psychiatry 2001; 6: 179-185. (Pubitemid 32187868)
    • (2001) Molecular Psychiatry , vol.6 , Issue.2 , pp. 179-185
    • Kaiser, R.1    Tremblay, P.-B.2    Schmider, J.3    Henneken, M.4    Dettling, M.5    Muller-Oerlinghausen, B.6    Uebelhack, R.7    Roots, I.8    Brockmoller, J.9
  • 39
    • 0011118362 scopus 로고
    • Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions
    • Hozumi N, Tonegawa S. Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc Natl Acad Sci USA 1976; 73: 3628-3632.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 3628-3632
    • Hozumi, N.1    Tonegawa, S.2
  • 41
    • 0035669353 scopus 로고    scopus 로고
    • Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims
    • DOI 10.1016/S0893-133X(01)00310-4, PII S0893133X01003104
    • Arango V, Underwood MD, Boldrini M, Tamir H, Kassir SA, Hsiung S et al. Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsychopharmacology 2001; 25: 892-903. (Pubitemid 34031894)
    • (2001) Neuropsychopharmacology , vol.25 , Issue.6 , pp. 892-903
    • Arango, V.1    Underwood, M.D.2    Boldrini, M.3    Tamir, H.4    Kassir, S.A.5    Hsiung, S.-C.6    Chen, J.J.-X.7    Mann, J.J.8
  • 42
    • 23744490895 scopus 로고    scopus 로고
    • Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: A systematic review and meta-analysis
    • DOI 10.1038/sj.mp.4001663
    • Cho HJ, Meira-Lima I, Cordeiro Q, Michelon L, Sham P, Vallada H et al. Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: A systematic review and meta-analysis. Mol Psychiatry 2005; 10: 771-781. (Pubitemid 41129050)
    • (2005) Molecular Psychiatry , vol.10 , Issue.8 , pp. 771-781
    • Cho, H.J.1    Meira-Lima, I.2    Cordeiro, Q.3    Michelon, L.4    Sham, P.5    Vallada, H.6    Collier, D.A.7
  • 43
    • 0031423428 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms: Ethnic difference and possible association with bipolar affective disorder
    • Kunugi H, Hattori M, Kato T, Tatsumi M, Sakai T, Sasaki T et al. Serotonin transporter gene polymorphisms: Ethnic difference and possible association with bipolar affective disorder. Mol Psychiatry 1997; 2: 457-462.
    • (1997) Mol Psychiatry , vol.2 , pp. 457-462
    • Kunugi, H.1    Hattori, M.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Sasaki, T.6
  • 44
    • 34548319329 scopus 로고    scopus 로고
    • Molecular studies of major depressive disorder: The epigenetic perspective
    • DOI 10.1038/sj.mp.4001992, PII 4001992
    • Mill J, Petronis A. Molecular studies of major depressive disorder: The epigenetic perspective. Mol Psychiatry 2007; 12: 799-814. (Pubitemid 47347791)
    • (2007) Molecular Psychiatry , vol.12 , Issue.9 , pp. 799-814
    • Mill, J.1    Petronis, A.2
  • 46
    • 77955611775 scopus 로고    scopus 로고
    • Methylation matters: Interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma
    • van IMH, Caspers K, Bakermans-Kranenburg MJ, Beach SR, Philibert R. Methylation matters: Interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma. Biol Psychiatry 2010; 68: 405-407.
    • (2010) Biol Psychiatry , vol.68 , pp. 405-407
    • Van, I.M.H.1    Caspers, K.2    Bakermans-Kranenburg, M.J.3    Beach, S.R.4    Philibert, R.5
  • 50
    • 47149112211 scopus 로고    scopus 로고
    • DNA methylation changes in schizophrenia and bipolar disorder
    • Connor CM, Akbarian S. DNA methylation changes in schizophrenia and bipolar disorder. Epigenetics 2008; 3: 55-58.
    • (2008) Epigenetics , vol.3 , pp. 55-58
    • Connor, C.M.1    Akbarian, S.2
  • 51
    • 21844439212 scopus 로고    scopus 로고
    • Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders
    • DOI 10.1038/sj.mp.4001662
    • Kato T, Iwamoto K, Kakiuchi C, Kuratomi G, Okazaki Y. Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders. Mol Psychiatry 2005; 10: 622-630. (Pubitemid 40961732)
    • (2005) Molecular Psychiatry , vol.10 , Issue.7 , pp. 622-630
    • Kato, T.1    Iwamoto, K.2    Kakiuchi, C.3    Kuratomi, G.4    Okazaki, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.