cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 301, Issue 2, 2011, Pages

  Genders, A J ^a   Bradley, E A ^a   Rattigan, S ^a   Richards, S M ^a  

^a UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Blood flow; Cyclic guanosine monophosphate; Insulin and glucose delivery to muscle; Microvascular blood flow

Indexed keywords

1 METHYLXANTHINE; CYCLIC GMP PHOSPHODIESTERASE; INSULIN; ISOPHANE INSULIN; ISOPROTEIN; MESSENGER RNA; PHOSPHODIESTERASE I; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE V; PHOSPHODIESTERASE VI; XANTHINE OXIDASE; ZAPRINAST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; BLOOD VESSEL; BOLUS INJECTION; COMPETITIVE INHIBITION; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG POTENTIATION; GASTROCNEMIUS MUSCLE; GLUCOSE TRANSPORT; HYPERINSULINEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN INFUSION; INSULIN METABOLISM; INSULIN SENSITIVITY; MALE; MICROVASCULARIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SMOOTH MUSCLE FIBER; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; BLOOD GLUCOSE; CELLS, CULTURED; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 2; ENERGY METABOLISM; GLUCOSE CLAMP TECHNIQUE; HYPERINSULINISM; INSULIN; MALE; MICROCIRCULATION; MUSCLE, SKELETAL; MUSCLE, SMOOTH, VASCULAR; PHOSPHODIESTERASE INHIBITORS; PURINONES; RATS; RATS, WISTAR;

EID: 79960777816     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00691.2010     Document Type: Article

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