Molecular characterisation of 36 oat varieties and in vitro assessment of their suitability for coeliacs' diet

Journal of Cereal Science

Volumn 54, Issue 1, 2011, Pages 110-115

  Ballabio, C ^a   Uberti, F ^a   Manferdelli, S ^b   Vacca, E ^b   Boggini, G ^c   Redaelli, R ^c   Catassi, C ^d   Lionetti, E ^e   Penas E ^f   Restani, P ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b R and D Infant and Nutrition   (Italy)

^c Istituto Sperimentale per la Cerealicoltura   (Italy)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e UNIVERSITY OF CATANIA   (Italy)

^f INSTITUTE OF FOOD SCIENCE   (Spain)

Author keywords

Coeliac disease; ELISA; Gluten; Immunoblotting; Oats

Indexed keywords

AVENA; HORDEUM; SECALE CEREALE; TRITICUM AESTIVUM;

EID: 79960741608     PISSN: 07335210     EISSN: 10959963     Source Type: Journal    
DOI: 10.1016/j.jcs.2011.04.004     Document Type: Article

References (38)

1. Arentz-Hansen H., Fleckenstein B., Molberg Ø., Scott H., Koning F., Jung G., Roepstorff P., Lundin K.E., Sollid L.M. The molecular basis for oats intolerance in patients with celiac disease. PLoS Medicine 2004, 1:84-92.
2. Baker P.G., Read A.E. Oats and barley toxicity in coeliac patients. Postgraduate Medicine Journal 1976, 52:264-268.
3. Barker J.M., Liu E. Celiac disease: pathophysiology, clinical manifestations, and associated autoimmune conditions. Advances in Pediatrics 2008, 55:349-365.
4. Braaten T.J., Wood P.J., Scott F.W., Wolynetz M.S., Lowe M.K., Bradley-White P. Oat β-glucan reduces blood cholesterol concentration in hypercholesterolemic subjects. European Journal of Clinical Nutrition 1994, 48:465-474.
5. Dissanayake A.S., Truelove S.C., Whitehead R. Lack of harmful effect of oats on small-intestinal mucosa in coeliac disease. British Medical Journal 1974, 4:189-191.
6. Dube C., Rostom A., Sy R., Cranney A., Saloojee N., Garritty C., Sampson M., Zhang L., Yazdi F., Mamaladze V., Pan I., Macneil J., Mack D., Patel D., Moher D. The prevalence of celiac disease in average-risk and at-risk western European populations: a systematic review. Gastroenterology 2005, 128:S57-S67.
7. Concerning the composition and labelling of foodstuffs suitable for people intolerant to gluten. Official Journal of the European Union 21 January 2009, 3. European Commission Regulation (EC) No 41/2009 of 20 January 2009, L 16.
8. Fasano A., Catassi C. Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum. Gastroenterology 2001, 120:636-651.
9. Fasano A., Berti I., Gerarduzzi T., Not T., Colletti R.B., Drago S., Elitsur Y., Green P.H., Guandalini S., Hill I.D., Pietzak M., Ventura A., Thorpe M., Kryszak D., Fornaroli F., Wasserman S.S., Murray J.A., Horvath K. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Archives of Internal Medicine 2003, 163:286-292.
10. García E., Llorente M., Hernando A., Kieffer R., Wieser H., Méndez E. Development of a general procedure for complete extraction of gliadins for heat processed and unheated foods. European Journal of Gastroenterology & Hepatology 2005, 17(5):523-524.
11. Guttormsen V., Løvik A., Bye A., Bratlie J., Mørkrid L., Lundin K.E.A. No induction of anti-avenin IgA by oats in adult, diet-trated coeliac disease. Scandinavian Journal OfGastroenterology 2008, 43:161-165.
12. Hardman C.M., Garioch J.J., Leonard J.N., Thomas H.J., Walker M.M., Lortan J.E., Lister A., Fry L. Absence of toxicity of oats in patients with dermatitis herpetiformis. The New England Journal of Medicine 1997, 337:1884-1887.
13. Hoffenberg E.J., Haas J., Drescher A., Bamhurst R., Osberg I., Bao F. A trial of oats in children with newly diagnosed celiac disease. Journal of Pediatrics 2000, 137:361-366.
14. Högberg L., Laurin P., Fälth-Magnusson K., Grant C., Grodzinsky E., Jansson G., Ascher H., Browaldh L., Hammersjö J.A., Lindberg E., Myrdal U., Stenhammar L. Oats to children with newly diagnosed coeliac disease: a randomised double blind study. Gut 2004, 53:649-654.
15. Holm K., Mäki M., Vuolteenaho N., Mustalahti K., Ashorn M., Ruuska T., Kaukinen K. Oats in the treatment of childhood coeliac disease: a 2-year controlled trial and a long-term clinical follow-up study. Alimentary Pharmacology & Therapeutics 2006, 23:1463-1472.
16. Immer U., Haas-Lauterbach S. Gluten detection. Molecular Biological and Immunological Techniques and Applications for Food Chemists 2010, 359-376. John Wiley & Sons, Inc, Hoboken, New Jersey. B. Popping, C. Diaz-Amigo, K. Hoenicke (Eds.).
17. Janatuinen E.K., Kemppainen T.A., Julkunen R.J., Kosma V.M., Mäki M., Heikkinen M., Uusitupa M.I. No harm from five-year ingestion of oats in coeliac disease. Gut 2002, 50:332-335.
18. Janatuinen E.K., Kemppainen T.A., Pikkarainen P.H., Holm K.H., Kosma V.M., Uusitupa M.I., Mäki M., Julkunen R.J. Lack of cellular and humoral immunological responses to oats in adults with coeliac disease. Gut 2000, 46:327-331.
19. Janatuinen E.K., Pikkarainen P.H., Kemppainen T.A., Kosma V.-M., Järvinen R.M.K., Uusitupa M.I.J., Julkunen R.J.K. A comparison of diets with and without oats in adults with coeliac disease. The New England Journal of Medicine 1995, 333:1033-1037.
20. Kanerva P.M., Sontag-Strohm T.S., Ryöppy P.H., Alho-Lehto P., Salovaara H.O. Analysis of barley contamination in oats using R5 and ω-gliadin antibodies. Journal of Cereal Science 2006, 44:347-352.
21. Kemppainen T.A., Heikkinen M.T., Ristikankare M.K., Kosma V.M., Sontag-Strohm T.S., Brinck O., Salovaara H.O., Julkunen R.J. Unkilned and large amounts of oats in the celiac disease diet: a randomized, controlled study. Scandinavian Journal of Gastroenterology 2008, 43:1094-1101.
22. Kemppainen T., Janatuinen E., Holm K., Kosma V.M., Heikkinen M., Mäki M., Laurila K., Uusitupa M., Julkunen R. No observed local immunological response at cell level five years of oats in adult coeliac disease. Scandinavian Journal of Gastroenterology 2007, 42:54-59.
23. Koskinen O., Villanen M., Korponay-Szabo I., Lindfors K., Mäki M., Kaukinen K. Oats do not induce systemic or mucosal autoantibody response in children with coeliac disease. Journal of Pediatric Gastroenterology and Nutrition 2009, 48(5):559-565.
24. Lundin K.E., Nilsen E.M., Scott H.G., Løberg E.M., Gjøen A., Bratlie J., Skar V., Mendez E., Løvik A., Kett K. Oats induced villous atrophy in coeliac disease. Gut 2003, 52:1649-1652.
25. Marsh M.N. Gluten, major histocompatibility complex and the small intestine: a molecular and immunobiologic approach to the spectrum of gluten sensitivity (" celiac sprue" ). Gastroenterology 1992, 102:330-354.
26. Méndez E., Vela C., Immer U., Janssen F.W. Report of a collaborative trial to investigate the performance of the R5 enzyme linked immunoassay to determine gliadin in gluten-free food. European Journal of Gastroenterology & Hepatology 2005, 17:1053-1063.
27. Neuhoff V., Arold N., Taube D., Ehrhardt W. Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using coomassie brilliant blue G-250 and R-250. Electrophoresis 1988, 9:255-262.
28. Peräaho M., Kaukinen K., Mustalahti K., Vuolteenaho N., Mäki M., Laippala P., Collin P. Effect of an oats-containing gluten-free diet on symptoms and quality of life in coeliac disease. A randomized study. Scandinavian Journal of Gastroenterology 2004, 39(1):27-31.
29. Reunala T., Collin P., Holm K., Pikkarainen P., Miettinen A., Vuolteenaho N., Mäki M. Tolerance to oats in dermatitis herpetiformis. Gut 1998, 43:490-493.
30. Sadiq Butt M., Tahir-Nadeem M., Khan M.K.I., Shabir R., Butt M.S. Oat: unique among the cereals. European Journal of Nutrition 2008, 47:68-79.
31. Sood A., Midha V., Sood N., Malhotra V. Adult celiac disease in Northern India. Indian Journal of Gastroenterology 2003, 22:124-126.
32. Srinivasan U., Leonard N., Jones E., Kasarda D.D., Weir D.G., O'Farrelly C., Feighery C. Absence of oats toxicity in adult coeliac disease. British Medicine Journal 1996, 313:1300-1301.
33. Storsrud S., Olsson M., Arvidsson Lenner R., Nilsson L.A., Nilsson O., Kilander A. Adult coeliac patients do tolerate large amounts of oats. European Journal of Clinical Nutrition 2003, 57:163-169.
34. Vader L.W., de Ru A., van der Wal Y., Kooy Y.M., Benckhuijsen W., Mearin M.L., Drijfhout J.W., van Veelen P., Koning F. Specificity of tissue transglutaminase explains cereal toxicity in celiac disease. Journal of Experimental Medicine 2002, 195:643-649.
35. Wahab P.J., Crusius J.B.A., Meijer J.W.R., Goerres M.S., Mulder C.J.J. Gluten challenge in borderline gluten sensitive enteropathy. American Journal of Gastroenterology 2001, 96:1464-1469.
36. Wieser H. Prolamins in cereals. Changing Features of Coeliac Disease 1998, 25-30. The Finnish Coeliac Society, Tampere. S. Lohiniemi, P. Collin, M. Mäki (Eds.).
37. Wieser H., Koehler P. The biochemical basis of celiac disease. Cereal Chemistry 2008, 85(1):1-13.
38. Wood P.J., Braaten J.A., Scott F.D., Riedel K.D., Wolynetz M.S., Collins M.W. Effect of dose and modification on viscous oat gum on plasma glucose and insulin following an oral glucose load. British Journal of Nutrition 1994, 72:731-743.