A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing

BMC Genomics

Volumn 12, Issue , 2011, Pages

  Meylan, Sylvain ^a   Groner, Anna C ^a   Ambrosini, Giovanna ^a,b   Malani, Nirav ^c   Quenneville, Simon ^a   Zangger, Nadine ^a   Kapopoulou, Adamandia ^a   Kauzlaric, Annamaria ^a   Rougemont, Jacques ^a   Ciuffi, Angela ^d   Bushman, Frederic D ^c   Bucher, Philipp ^a,b   Trono, Didier ^a  

^a EPFL   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Chromatin; Heterochromatin; Histone modifications; KAP1; KRAB zinc finger proteins; Transcriptional repression

Indexed keywords

HISTONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR KRAB; TRANSCRIPTION FACTOR KRAP1; UNCLASSIFIED DRUG; REPRESSOR PROTEIN; TRIM28 PROTEIN, HUMAN; ZNF350 PROTEIN, HUMAN;

ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; EUCHROMATIN; GENE ACTIVITY; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; GENETIC CORRELATION; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; MOLECULAR GENETICS; PROTEIN FUNCTION; CHROMATIN; GENETIC TRANSCRIPTION; GENETICS; GENOMICS; HELA CELL; METABOLISM;

VERTEBRATA;

CHROMATIN; GENE SILENCING; GENOMICS; HELA CELLS; HISTONES; HUMANS; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

EID: 79960687678     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-12-378     Document Type: Article

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