Uraemic serum induces dysfunction of vascular endothelial cells: Role of ubiquitin-proteasome pathway

Experimental Physiology

Volumn 96, Issue 8, 2011, Pages 801-815

  Feng, Bing ^a   Zhang, Yao Quan ^b   Mu, Jiao ^a   Yuan, Fa Huan ^a   Ye, Zi Lin ^a   Qi, Wei ^a   Guo, Yan Hong ^a   Zeng, Wei ^a   Luo, Zhi Feng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GLYCOPROTEIN E1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; PROTEASOME; PYRROLIDINE DITHIOCARBAMATE; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; ENDOTHELIAL DYSFUNCTION; GENE EXPRESSION; IN VITRO STUDY; NONHUMAN; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPECTROFLUOROMETRY; UREMIA; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

EID: 79960666556     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2011.058149     Document Type: Article

References (43)

1. Amabile N, Guerin AP, Leroyer A, Mallat Z, Nguyen C, Boddaert J, London GM, Tedgui A & Boulanger CM (2005). Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure. J Am Soc Nephrol 16, 3381-3388.
2. Amagaya S, Harada K, Miyake A, Iwama H & Ogihara Y (1989). A new pharmacological testing method-different effects of levamisole and the serum of mice orally treated with levamisole on mitogenic activity of lipopolysaccharide. Chem Pharm Bull (Tokyo) 37, 1117-1119.
3. Beg AA, Finco TS, Nantermet PV & Baldwin AS Jr (1993). Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation. Mol Cell Biol 13, 3301-3310.
4. Carbó C, Arderiu G, Escolar G, Fusté B, Cases A, Carrascal M, Abián J & Díaz-Ricart M (2008). Differential expression of proteins from cultured endothelial cells exposed to uremic versus normal serum. Am J Kidney Dis 51, 603-612.
5. Cardinal H, Raymond MA, Hebert MJ & Madore F (2007). Uraemic plasma decreases the expression of ABCA1, ABCG1 and cell-cycle genes in human coronary arterial endothelial cells. Nephrol Dial Transplant 22, 409-416.
6. Cokic VP, Beleslin-Cokic BB, Noguchi CT & Schechter AN (2007). Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity. Nitric Oxide 16, 371-378.
7. Dignat-George F & Sampol J (2000). Circulating endothelial cells in vascular disorders: new insights into an old concept. Eur J Haematol 65, 215-220.
8. Di Marco GS, Reuter S, Hillebrand U, Amler S, Konig M, Larger E, Oberleithner H, Brand E, Pavenstadt H & Brand M (2009). The soluble VEGF receptor sFlt1 contributes to endothelial dysfunction in CKD. J Am Soc Nephrol 20, 2235-2245.
9. Dou L, Jourde-Chiche N, Faure V, Cerini C, Berland Y, Dignat-George F & Brunet P (2007). The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells. J Thromb Haemost 5, 1302-1308.
10. Dursun I, Poyrazoglu HM, Gunduz Z, Ulger H, Yykylmaz A, Dusunsel R, Patyroglu T & Gurgoze M (2009). The relationship between circulating endothelial microparticles and arterial stiffness and atherosclerosis in children with chronic kidney disease. Nephrol Dial Transplant 24, 2511-2518.
11. Fasoli G, Esposito C, Cornacchia F, De Mauri A, Grosjean F, Mangione F, Plati A, Villa L & Dal Canton A (2006). Uremic serum induces proatherogenic changes in human endothelial cells. J Nephrol 19, 599-604.
12. Faure V, Dou L, Sabatier F, Cerini C, Sampol J, Berland Y, Brunet P & Dignat-George F (2006). Elevation of circulating endothelial microparticles in patients with chronic renal failure. J Thromb Haemost 4, 566-573.
13. Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C & Quest AF (2000). Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells. Proc Natl Acad Sci U S A 97, 14334-14339.
14. Feng B, Zhang Y, Mu J, Ye Z, Zeng W, Qi W, Luo Z, Guo Y, Yang X & Yuan F (2010). Preventive effect of a proteasome inhibitor on the formation of accelerated atherosclerosis in rabbits with uremia. J Cardiovasc Pharmacol 55, 129-138.
15. Glickman MH & Ciechanover A (2002). The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82, 373-428.
16. Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E & Ping P (2009). Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics 8, 302-315.
17. Gomes AV, Zong C, Edmondson RD, Li X, Stefani E, Zhang J, Jones RC, Thyparambil S, Wang GW, Qiao X, Bardag-Gorce F & Ping P (2006). Mapping the murine cardiac 26S proteasome complexes. Circ Res 99, 362-371.
18. 15N]nitrate in biological fluids. Anal Biochem 126, 131-138.
19. Herrmann J, Lerman LO & Lerman A (2010). On to the road to degradation: atherosclerosis and the proteasome. Cardiovasc Res 85, 291-302.
20. Hiroi T, Deming CB, Zhao H, Hansen BS, Arkenbout EK, Myers TJ, Rioret WJ, McDevitt MA & Rade JJ (2008). Bortezomib improves endothelial thromboresistance via induction of KLF transcription factors. Blood (ASH Annual Meeting Abstracts) 112, 1890.
21. Hochrainer K & Lipp J (2007). Ubiquitylation within signaling pathways in- and outside of inflammation. Thromb Haemost 97, 370-377.
22. Iwama H, Amagaya S & Ogihara Y (1987). Effect of shosaikoto, a Japanese and Chinese traditional herbal medicinal mixture, on the mitogenic activity of lipopolysaccharide: a new pharmacological testing method. J Ethnopharmacol 21, 45-53.
23. Kipshidze N, Nikolaychik V, Muckerheidi M, Keelan MH, Chekanov V, Maternowski M, Chawla P, Hernandez I, Iyer S, Dangas G, Sahota H, Leon MB, Roubin G & Moses JW (2001). Effect of short pulsed nonablative infrared laser irradiation on vascular cells in vitro and neointimal hyperplasia in a rabbit balloon injury model. Circulation 104, 1850-1855.
24. Kotamraju S, Tampo Y, Kalivendi SV, Joseph J, Chitambar CR & Kalyanaraman B (2004). Nitric oxide mitigates peroxide-induced iron-signaling, oxidative damage, and apoptosis in endothelial cells: role of proteasomal function? Arch Biochem Biophys 423, 74-80.
25. 2-induced transferrin receptor-dependent apoptosis in endothelial cells: role of ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A 100, 10653-10658.
26. Liu W, Liu P, Tao S, Deng Y, Li X, Lan T, Zhang X, Guo F, Huang W, Chen F, Huang H & Zhou SF (2008). Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose. Arch Biochem Biophys 475, 128-134.
27. Meijers BK, Van Kerckhoven S, Verbeke K, Dehaen W, Vanrenterghem Y, Hoylaerts MF & Evenepoel P (2009). The uremic retention solutep-cresyl sulfate and markers of endothelial damage. Am J Kidney Dis 54, 891-901.
28. Merino A, Portoles J, Selgas R, Ojeda R, Buendia P, Ocana J, Bajo MA, del Peso G, Carracedo J, Ramirez R, Martin-Malo A & Aljama P (2010). Effect of different dialysis modalities on microinflammatory status and endothelial damage. Clin J Am Soc Nephrol 5, 227-234.
29. Morris ST, McMurray JJ, Rodger RS & Jardine AG (2000). Impaired endothelium-dependent vasodilatation in uraemia. Nephrol Dial Transplant 15, 1194-1200.
30. Musial A & Eissa NT (2001). Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway. J Biol Chem 276, 24268-24273.
31. Parfrey PS & Harnett JD (1994). Cardiac disease in chronic uremia. Pathophysiology and clinical epidemiology. ASAIO J 40, 121-129.
32. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer M, Raij L, Spinosa DJ & Wilson PW (2003). Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension 42, 1050-1065.
33. Serradell M, Diaz-Ricart M, Cases A, Zurbano MJ, Lopez-Pedret J, Arranz O, Ordinas A & Escolar G (2002). Uremic medium causes expression, redistribution and shedding of adhesion molecules in cultured endothelial cells. Haematologica 87, 1053-1061.
34. Shen J, Reis J, Morrison DC, Papasian C, Raghavakaimal S, Kolbert C, Qureshi AA, Vogel SN & Qureshi N (2006). Key inflammatory signaling pathways are regulated by the proteasome. Shock 25, 472-484.
35. Stangl K & Stangl V (2010). The ubiquitin-proteasome pathway and endothelial (dys)function. Cardiovasc Res 85, 281-290.
36. Stangl V, Lorenz M, Meiners S, Ludwig A, Bartsch C, Moobed M, Vietzke A, Kinkel HT, Baumann G & Stangl K (2004). Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway. FASEB J 18, 272-279.
37. Stinghen AE, Gonçalves SM, Martines EG, Nakao LS, Riella MC, Aita CA & Pecoits-Filho R (2009). Increased plasma and endothelial cell expression of chemokines and adhesion molecules in chronic kidney disease. Nephron Clin Pract 111, c117-c126.
38. Thomas S, Kotamraju S, Zielonka J, Harder DR & Kalyanaraman B (2007). Hydrogen peroxide induces nitric oxide and proteosome activity in endothelial cells: a bell-shaped signaling response. Free Radic Biol Med 42, 1049-1061.
39. Tonelli M, Wiebe N, Culleton B, House A, Rabbat C, Fok M, McAlister F & Garg AX (2006). Chronic kidney disease and mortality risk: a systematic review. J Am Soc Nephrol 17, 2034-2047.
40. Vieira O, Escargueil-Blanc I, Jürgens G, Borner C, Almeida L, Salvayre R & Nègre-Salvayre A (2000). Oxidized LDLs alter the activity of the ubiquitin-proteasome pathway: potential role in oxidized LDL-induced apoptosis. FASEB J 14, 532-542.
41. Whitsett J, Picklo MJ Sr & Vasquez-Vivar J (2007). 4-Hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation. Arterioscler Thromb Vasc Biol 27, 2340-2347.
42. Xu J, Wu Y, Song P, Zhang M, Wang S & Zou MH (2007). Proteasome-dependent degradation of guanosine 5-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus. Circulation 116, 944-953.
43. Zhang R, Xu Y, Fu H, Wang J, Jin L & Li S (2009). Urocortin induced expression of COX-2 and ICAM-1 via corticotrophin-releasing factor type 2 receptor in rat aortic endothelial cells. Br J Pharmacol 158, 819-829.