Identification of azurocidin as a potential periodontitis biomarker by a proteomic analysis of gingival crevicular fluid

Proteome Science

Volumn 9, Issue , 2011, Pages

  Choi, Young Jin ^a   Heo, Sun Hee ^a   Lee, Jae Mok ^a   Cho, Je Yoel ^a  

^a Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AZUROCIDIN; CALGRANULIN B; CATALASE; CYSTATIN B; CYTOKERATIN 2; GELATINASE B; GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE; HEMOGLOBIN BETA CHAIN; LEUKOCYTE ELASTASE; MYELOBLASTIN; NUCLEOSIDE DIPHOSPHATE KINASE B; PHOSPHOTRANSFERASE; SECRETORY COMPONENT; STEFIN A; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE MARKER; ENZYME LINKED IMMUNOSORBENT ASSAY; GINGIVITIS; HUMAN; LIQUID CHROMATOGRAPHY; MACROPHAGE; MAJOR CLINICAL STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; OSTEOCLAST; PERIODONTITIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; UPREGULATION;

EID: 79960654946     PISSN: None     EISSN: 14775956     Source Type: Journal    
DOI: 10.1186/1477-5956-9-42     Document Type: Article

References (38)

1. Kinney JS, Ramseier CA, Giannobile WV. Oral fluid-based biomarkers of alveolar bone loss in periodontitis. Ann N Y Acad Sci 2007, 1098:230-251. 10.1196/annals.1384.028, 2570328, 17435132.
2. Albandar JM. Periodontal diseases in North America. Periodontol 2000 2002, 29:31-69. 10.1034/j.1600-0757.2002.290103.x, 12102702.
3. Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link?. Lancet 1997, 350:430-436. 10.1016/S0140-6736(97)03079-1, 9259669.
4. Seymour GJ, Ford PJ, Cullinan MP, Leishman S, Yamazaki K. Relationship between periodontal infections and systemic disease. Clin Microbiol Infect 2007, 13(Suppl 4):3-10.
5. Demmer RT, Behle JH, Wolf DL, Handfield M, Kebschull M, Celenti R, Pavlidis P, Papapanou PN. Transcriptomes in healthy and diseased gingival tissues. J Periodontol 2008, 79:2112-2124. 10.1902/jop.2008.080139, 2637651, 18980520.
6. Hefti AF. Periodontal probing. Crit Rev Oral Biol Med 1997, 8:336-356. 10.1177/10454411970080030601, 9260047.
7. Bragger U. Radiographic parameters: biological significance and clinical use. Periodontol 2000 2005, 39:73-90. 10.1111/j.1600-0757.2005.00128.x, 16135065.
8. Loos BG, Tjoa S. Host-derived diagnostic markers for periodontitis: do they exist in gingival crevice fluid?. Periodontol 2000 2005, 39:53-72. 10.1111/j.1600-0757.2005.00129.x, 16135064.
9. Offenbacher S, Barros SP, Beck JD. Rethinking periodontal inflammation. J Periodontol 2008, 79:1577-1584. 10.1902/jop.2008.080220, 18673013.
10. Embery G, Waddington R. Gingival crevicular fluid: biomarkers of periodontal tissue activity. Adv Dent Res 1994, 8:329-336.
11. Lamster IB, Ahlo JK. Analysis of gingival crevicular fluid as applied to the diagnosis of oral and systemic diseases. Ann N Y Acad Sci 2007, 1098:216-229. 10.1196/annals.1384.027, 17435131.
12. Champagne CM, Buchanan W, Reddy MS, Preisser JS, Beck JD, Offenbacher S. Potential for gingival crevice fluid measures as predictors of risk for periodontal diseases. Periodontol 2000 2003, 31:167-180. 10.1034/j.1600-0757.2003.03110.x, 12657001.
13. Armitage GC. Analysis of gingival crevice fluid and risk of progression of periodontitis. Periodontol 2000 2004, 34:109-119. 10.1046/j.0906-6713.2002.003427.x, 14717858.
14. Hu S, Loo JA, Wong DT. Human body fluid proteome analysis. Proteomics 2006, 6:6326-6353. 10.1002/pmic.200600284, 2910092, 17083142.
15. Pradeep AR, Kumar MS, Ramachandraprasad MV, Shikha C. Gingival crevicular fluid levels of neopterin in healthy subjects and in patients with different periodontal diseases. J Periodontol 2007, 78:1962-1967. 10.1902/jop.2007.070096, 18062118.
16. Heo SH, Lee SJ, Ryoo HM, Park JY, Cho JY. Identification of putative serum glycoprotein biomarkers for human lung adenocarcinoma by multilectin affinity chromatography and LC-MS/MS. Proteomics 2007, 7:4292-4302. 10.1002/pmic.200700433, 17963278.
17. Park HJ, Kim BG, Lee SJ, Heo SH, Kim JY, Kwon TH, Lee EB, Ryoo HM, Cho JY. Proteomic profiling of endothelial cells in human lung cancer. J Proteome Res 2008, 7:1138-1150. 10.1021/pr7007237, 18220333.
18. Park ES, Cho HS, Kwon TG, Jang SN, Lee SH, An CH, Shin HI, Kim JY, Cho JY. Proteomics analysis of human dentin reveals distinct protein expression profiles. J Proteome Res 2009, 8:1338-1346. 10.1021/pr801065s, 19193101.
19. Keller A, Nesvizhskii AI, Kolker E, Aebersold R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 2002, 74:5383-5392. 10.1021/ac025747h, 12403597.
20. Nesvizhskii AI, Keller A, Kolker E, Aebersold R. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem 2003, 75:4646-4658. 10.1021/ac0341261, 14632076.
21. Cho JY, Lee M, Ahn JM, Park ES, Cho JH, Lee SJ, Kim BG, Heo SH, Park HJ, Zerbini LF, et al. Proteomic analysis of a PDEF Ets transcription factor-interacting protein complex. J Proteome Res 2009, 8:1327-1337. 10.1021/pr800683b, 19203193.
22. Seul KJ, Cho HS, Heo SH, Baek WY, Kim JE, Park EK, Choi JY, Ryoo HM, Cho JY. Osteoblast-specific expression of MEF induces osteopenia through downregulation of osteoblastogenesis and upregulation of osteoclastogenesis. J Bone Miner Res 2010, 26:341-350.
23. Soehnlein O, Lindbom L. Neutrophil-derived azurocidin alarms the immune system. J Leukoc Biol 2009, 85:344-351.
24. Soehnlein O, Xie X, Ulbrich H, Kenne E, Rotzius P, Flodgaard H, Eriksson EE, Lindbom L. Neutrophil-derived heparin-binding protein (HBP/CAP37) deposited on endothelium enhances monocyte arrest under flow conditions. J Immunol 2005, 174:6399-6405.
25. Pisano E, Cabras T, Montaldo C, Piras V, Inzitari R, Olmi C, Castagnola M, Messana I. Peptides of human gingival crevicular fluid determined by HPLC-ESI-MS. Eur J Oral Sci 2005, 113:462-468. 10.1111/j.1600-0722.2005.00246.x, 16324135.
26. Ngo LH, Veith PD, Chen YY, Chen D, Darby IB, Reynolds EC. Mass spectrometric analyses of peptides and proteins in human gingival crevicular fluid. J Proteome Res 2010, 9:1683-1693. 10.1021/pr900775s, 20020772.
27. Bostanci N, Heywood W, Mills K, Parkar M, Nibali L, Donos N. Application of Label-Free Absolute Quantitative Proteomics in Human Gingival Crevicular Fluid by LC/MS(E) (Gingival Exudatome). J Proteome Res 2010, 9:2191-9. 10.1021/pr900941z, 20205380.
28. Zimmer M, Medcalf RL, Fink TM, Mattmann C, Lichter P, Jenne DE. Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter. Proc Natl Acad Sci USA 1992, 89:8215-8219. 10.1073/pnas.89.17.8215, 49888, 1518849.
29. Shafer WM, Martin LE, Spitznagel JK. Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate. Infect Immun 1984, 45:29-35. 263254, 6376359.
30. Watorek W. Azurocidin -- inactive serine proteinase homolog acting as a multifunctional inflammatory mediator. Acta Biochim Pol 2003, 50:743-752.
31. Almeida RP, Vanet A, Witko-Sarsat V, Melchior M, McCabe D, Gabay JE. Azurocidin, a natural antibiotic from human neutrophils: expression, antimicrobial activity, and secretion. Protein Expr Purif 1996, 7:355-366. 10.1006/prep.1996.0053, 8776752.
32. Heinzelmann M, Platz A, Flodgaard H, Miller FN. Heparin binding protein (CAP37) is an opsonin for Staphylococcus aureus and increases phagocytosis in monocytes. Inflammation 1998, 22:493-507. 10.1023/A:1022398027143, 9793796.
33. Campanelli D, Detmers PA, Nathan CF, Gabay JE. Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties. J Clin Invest 1990, 85:904-915. 10.1172/JCI114518, 296509, 2312733.
34. Rasmussen PB, Bjorn S, Hastrup S, Nielsen PF, Norris K, Thim L, Wiberg FC, Flodgaard H. Characterization of recombinant human HBP/CAP37/azurocidin, a pleiotropic mediator of inflammation-enhancing LPS-induced cytokine release from monocytes. FEBS Lett 1996, 390:109-112. 10.1016/0014-5793(96)00639-4, 8706818.
35. Lorenzo J, Choi Y. Osteoimmunology. Immunol Rev 2005, 208:5-6. 10.1111/j.0105-2896.2005.00340.x, 16313336.
36. Takayanagi H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 2007, 7:292-304. 10.1038/nri2062, 17380158.
37. Theill LE, Boyle WJ, Penninger JM. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 2002, 20:795-823. 10.1146/annurev.immunol.20.100301.064753, 11861618.
38. Walsh MC, Kim N, Kadono Y, Rho J, Lee SY, Lorenzo J, Choi Y. Osteoimmunology: interplay between the immune system and bone metabolism. Annu Rev Immunol 2006, 24:33-63. 10.1146/annurev.immunol.24.021605.090646, 16551243.