Heparin binding protein (CAP37) is an opsonin for Staphylococcus aureus and increases phagocytosis in monocytes

Inflammation

Volumn 22, Issue 5, 1998, Pages 493-507

  Heinzelmann, Michael ^a,b   Platz, Andreas ^b   Flodgaard, Hans ^c   Miller, Frederick N ^a  

^a Dept of Physiology and Biophysics ^*  (United States)

^b University of Louisville School of Medicine   (United States)

^c NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN BINDING PROTEIN; OPSONIN; SUPEROXIDE;

ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; NONHUMAN; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS;

ANTIMICROBIAL CATIONIC PEPTIDES; BLOOD PROTEINS; CARRIER PROTEINS; GRANULOCYTES; HUMANS; INFLAMMATION; MONOCYTES; OPSONIN PROTEINS; PHAGOCYTOSIS; PROTEIN BINDING; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS; SUPEROXIDES;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 0031736509     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022398027143     Document Type: Article

References (43)

1. WRIGHT, S. D. Receptors for complement and the biology of phagocytosis. In Gallin J. I., Goldstein I. M., Snyderman R., editors. Inflammation: Basic Principles and Clinical Correlates. Raven Press Ltd., New York, New York, 1992. pp. 447-495.
2. KLEBANOFF, S. J. Oxygen metabolites from phagocytes. In Gallin J. I., Goldstein I. M., Snyderman R., editors. Inflammation: Basic Principles and Clinical Correlates. Raven Press, New York, New York, 1992. pp. 541-588.
3. ELSBACH, P., and J. WEISS. Oxygen-independent antimicrobial systems of phagocytes. In Gallin J. I., Goldstein I. M., Snyderman R., editors. Inflammation: Basic Principles and Clinical Correlates. Raven Press, New York, NY: 1992: pp. 603-636.
4. PEREIRA, H. A., W. M. SHAFER, J. POHL, L. E. MARTIN, and J. K. SPITZNAGEL. 1990. CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity. J. Clin. Invest. 85:1468-1476.
5. LEHRER, R. I., T. GANZ, and M. E. SELSTED. 1991. Defensins: endogenous antibiotic peptides of animal cells. Cell 64:229-230.
6. LEHRER, R. I., A. K. LICHTENSTEIN, and T. GANZ. 1993. Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu. Rev. Immunol. 11:105-128.
7. GABAY, J. E., and R. P. ALMEIDA. 1993. Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin. Curr. Opin. Immunol. 5:97-102.
8. GANZ, T., R. I. LEHRER. 1994. Defensins. Curr. Opin. Immunol. 6:584-589.
9. CAMPANELLI, D., P. A. DETMERS, C. F. NATHAN, and J. E. GABAY. 1990. Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties. J. Clin. Invest. 85:904-915.
10. FLODGAARD, H., E. OSTERGAARD, S. BAYNE, A. SVENDSEN, J. THOMSEN, M. ENGELS, and A. WOLLMER. 1991. Covalent structure of two novel neutrophile leucocyte-derived proteins of porcine and human origin. Neutrophile elastase homologues with strong monocyte and fibroblast chemotactic activities. Eump. J. Biochem. 197:535-547.
11. PEREIRA, H. A. 1995. CAP37, a neutrophil-derived multifunctional inflammatory mediator. J. Leukoc. Biol. 57:805-812.
12. RASMUSSEN, P. B., S. BJORN, S. HASTRUP, P. F. NIELSEN, K. NORRIS, L. THIM, F. C. WIBERG, and H. FLODGAARD. 1996. Characterization of recombinant human HBP/CAP37/azurocidin, a pleiotropic mediator of inflammation-enhancing LPS-induced cytokine release from monocytes. FEBS Lett. 390:109-112.
13. HEINZELMANN, M., M. A. MERCER-JONES, H. FLODGAARD, and F. N. MILLER. 1998. Heparin binding protein (CAP37) is internalized in monocytes and increases lipopolysaccharide-induced monocyte activation. J. Immunol. 160:5530-5536.
14. PAGE, A. R., and R. A. GOOD. 1958. A clinical and experimental study of the function of neutrophils in the inflammatory response. Am. J. Pathol. 34:645-669.
15. GALLIN, J. I. 1985. Neutrophil specific granule deficiency. Annu. Rev. Med. 36:263-274.
16. HENSON, P. M., D. E. DOHERTY, D. W. H. RICHES, P. E. PARSONS, and G. S. WORTHEN. 1994. LPS and Cytokines in Lung Injury. Marcel Dekker, Inc. New York, New York.
17. OSTERGAARD, E., and H. FLODGAARD. 1992. A neutrophil-derived proteolytic inactive elastase homologue (hHBP) mediates reversible contraction of fibroblasts and endothelial cell monolayers and stimulates monocyte survival and thrombospondin secretion. J. Leukoc. Biol. 51:316-323.
18. SHAFER, W. M., L. E. MARTIN, and J. K. SPITZNAGEL. 1986. Late intraphagosomal hydrogen ion concentration favors the in vitro antimicrobial capacity of a 37-kilodalton cationic granule protein of human neutrophil granulocytes. Infect. Immun. 53:651-655.
19. MERCER-JONES, M., M. HEINZELMANN, J. PEYTON, M. COOK, H. FLODGAARD, and W. G. CHEADLE. 1996. Monocyte recruitment increases survival in fecal peritonitis. Surg. Forum 47:106-108.
20. SHAFER, W. M., L. E. MARTIN, and J. K. SPITZNAGEL. 1984. Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate. Infect. Immun. 45:29-35.
21. ANDERSON, G. L., F. N. MILLER, and R. J. XIU. 1984. Inhibition of histamine-induced protein leakage in rat skeletal muscle by blockade of prostaglandin synthesis. Microvascular Research 28:51-61.
22. PERTICARARI, S., G. PRESANI, and E. BANFI. 1994. A new flow cytometric assay for the evaluation of phagocytosis and the oxidative burst in whole blood. J. Immunol. Methods 170:117-124.
23. SEGAL, A. W., M. GEISOW, R. GARCIA, A. HARPER, and R. MILLER. 1981. The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH. Nature 290:406-409.
24. OHKUMA, S., and B. POOLE. 1978. Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents. Proc. Natl. Acad. Sci. U.S.A. 75:3327-3331.
25. ROTHE, G., and G. VALET. 1990. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J. Leukoc. Biol. 47:440-448.
26. KAROLIN, J., L. B. A. JOHANSSON, L. STRANDBERG, and T. NY. 1994. Fluorescence and absorption spectroscopic properties of dipyrrometheneboron difluoride (bodipy) derivatives in liquids, lipid membranes, and proteins. Journal of the American Chemical Society 116:7801-7806.
27. SHAPIRO, H. M. 1995. In Practical Flow Cytornetry. 3rd ed. Wiley-Liss, Inc., New York, New York. pp. 229.
28. HED, J., G. HALLDEN, S. G. JOHANSSON, and P. LARSSON. 1987. The use of fluorescence quenching in flow cytofluorometry to measure the attachment and ingestion phases in phagocytosis in peripheral blood without prior cell separation. J. Immunol. Methods 101:119-125.
29. WRIGHT, A. E., and S. R. DOUGLAS. 1903. An experimental investigation of the role of the body fluids in connection with phagocytosis. Proc. R. Soc. Lond. 72:357-370.
30. KUHLMAN, M., K. JOINER, and R. A. EZEKOWlTZ. 1989. The human mannose-binding protein functions as an opsonin. J. Exp. Med. 169:1733-1745.
31. TOBIAS, P. S., K. SOLDAU, and R. J. ULEVITCH. 1986. Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum. J. Exp. Med. 164:777-793.
32. WRIGHT, S. D., P. S. TOBIAS, R. J. ULEVITCH, and R. A. RAMOS. 1989. Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages. J. Exp. Med. 170:1231-1241.
33. TOBIAS, P. S., K. SOLDAU, L. KLINE, J. D. LEE, K. KATO, T. P. MARTIN, and R. J. ULEVITCH. 1993. Cross-linking of lipopolysaccharide (LPS) to CD14 on THP-1 cells mediated by LPS-binding protein. J. Immunol. 150:3011-3021.
34. ULEVITCH, R. J., and P. S. TOBIAS. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437-457.
35. CAMPBELL, E. J. 1982. Human leukocyte elastase, cathepsin G, and lactoferrin: family of neutrophil granule glycoproteins that bind to an alveolar macrophage receptor. Proc. Natl. Acad. Sci. U.S.A. 79:6941-6945.
36. PEREIRA, H. A., J. K. SPITZNAGEL, J. POHL, D. E. WILSON, J. MORGAN, I. PALINGS, and J. W. LARRICK. 1990. CAP 37, a 37 kD human neutrophil granule cationic protein shares homology with inflammatory proteinases. Life Sci. 46:189-196.
37. PEREIRA, H. A., I. ERDEM, J. POHL, and J. K. SPITZNAGEL. 1993. Synthetic bactericidal peptide based on CAP37: a 37-kDa human neutrophil granule-associated cationic antimicrobial protein chemotactic for monocytes. Proc. Natl. Acad. Sci. U.S.A. 90:4733-4737.
38. IVERSEN, L. F., J. S. KASTRUP, S. E. BJORN, P. B. RASMUSSEN, F. C. WIBERG, H. J. FLODGAARD, and I. K. LARSEN. 1997. Structure of HBP, a multifunctional protein with a serine proteinase fold. Nat. Struct. Biol. 4:265-268.
39. MORTENSEN, R. F., A. P. OSMAND, T. F. LINT, and H. GEWURZ. 1976. Interaction of C-reactive protein with lymphocytes and monocytes: complement-dependent adherence and phagocytosis. J. Immunol. 117:774-781.
40. JOHNSTON, R. J., J. E. LEHMEYER, and L. A. GUTHRIE. 1976. Generation of superoxide anion and chemiluminescence by human monocytes during phagocytosis and on contact with surface-bound immunoglobulin G. J. Exp. Med. 143:1551-1556.
41. WRIGHT, S. D., and S. C. SILVERSTEIN. 1983. Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes. J. Exp. Med. 158:2016-2023.
42. YAMAMOTO, K., and R. J. JOHNSTON. 1984. Dissociation of phagocytosis from stimulation of the oxidative metabolic burst in macrophages. J. Exp. Med. 159:405-416.
43. LLOYD, A. R., and J. J. OPPENHEIM. 1992. Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response. Immunol. Today 13:169-172.