Transcriptomes in healthy and diseased gingival tissues

Journal of Periodontology

Volumn 79, Issue 11, 2008, Pages 2112-2124

  Demmer, Ryan T ^a   Behle, Jan H ^b   Wolf, Dana L ^b   Handfield, Martin ^c   Kebschull, Moritz ^b   Celenti, Romanita ^b   Pavlidis, Paul ^d   Papapanou, Panos N ^b  

^a Department of Medicine   (United States)

^b University of Florida ^*  (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Gene expression; Genomics; Infection; Microarray; Periodontitis

Indexed keywords

EID: 55749098815     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.080139     Document Type: Article

References (33)

1. Listgarten MA. Periodontal probing: What does it mean? J Clin Periodontol 1980;7:165-176.
2. Harper DS, Robinson PJ. Correlation of histometric, microbial, and clinical indicators of periodontal disease status before and after root planing. J Clin Periodontol 1987;14:190-196.
3. Hefti AF. Periodontal probing. Crit Rev Oral Biol Med 1997;8:336-356.
4. Brägger U. Radiographic parameters: Biological significance and clinical use. Periodontol 2000 2005;39:73-90.
5. Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab Invest 1976;34:235-249.
6. Listgarten MA, Helldén L. Relative distribution of bacteria at clinically healthy and periodontally diseased sites in humans. J Clin Periodontol 1978;5:115-132.
7. Socransky SS, Haffajee AD, Dzink JL. Relationship of subgingival microbial complexes to clinical features at the sampled sites. J Clin Periodontol 1988;15:440-444.
8. Bowers MR, Fisher LW, Termine JD, Somerman MJ. Connective tissue-associated proteins in crevicular fluid: Potential markers for periodontal diseases. J Periodontol 1989;60:448-451.
9. Mathur A, Michalowicz B, Castillo M, Aeppli D. Interleukin-1 alpha, interleukin-8 and interferon-alpha levels in gingival crevicular fluid. J Periodontal Res 1996;31:489-495.
10. Dongari-Bagtzoglou AI, Ebersole JL. Increased presence of interleukin-6 (IL-6) and IL-8 secreting fibroblast subpopulations in adult periodontitis. J Periodontol 1998;69:899-910.
11. Chung CH, Bernard PS, Perou CM. Molecular portraits and the family tree of cancer. Nat Genet 2002;32(Suppl.):533-540.
12. Quackenbush J. Microarray analysis and tumor classification. N Engl J Med 2006;354:2463-2472.
13. Haslett JN, Kunkel LM. Microarray analysis of normal and dystrophic skeletal muscle. Int J Dev Neurosci 2002;20:359-365.
14. Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ. Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 2002;70:462-473.
15. Haroutunian V, Katsel P, Schmeidler J. Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia. Neurobiol Aging. 2007 Sep 8. [Epub ahead of print].
16. Thornton S, Sowders D, Aronow B, et al. DNA microarray analysis reveals novel gene expression profiles in collagen-induced arthritis. Clin Immunol 2002;105:155-168.
17. van der Pouw Kraan TC, van Baarsen LG, Rustenburg F, Baltus B, Fero M, Verweij CL. Gene expression profiling in rheumatology. Methods Mol Med 2007;136:305-327.
18. Burke W. Genomics as a probe for disease biology. N Engl J Med 2003;349:969-974.
19. Izuhara K, Saito H. Microarray-based identification of novel biomarkers in asthma. Allergol Int 2006;55:361-367.
20. Papapanou PN, Abron A, Verbitsky M, et al. Gene expression signatures in chronic and aggressive periodontitis: A pilot study. Eur J Oral Sci 2004;112:216-223.
21. Lindhe J, Ranney RR, Lamster IB, et al. Consensus report: Periodontitis as a manifestation of systemic diseases. Ann Periodontol 1999;4:64.
22. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003;31:e15.
23. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003;100:9440-9445.
24. Lee HK, Braynen W, Keshav K, Pavlidis P. ErmineJ: Tool for functional analysis of gene expression data sets. BMC Bioinformatics 2005;6:269.
25. Khatri P, Voichita C, Kattan K, et al. Onto-Tools: New additions and improvements in 2006. Nucleic Acids Res 2007;35:W206-W211.
26. Brazma A, Hingamp P, Quackenbush J, et al. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet 2001;29:365-371.
27. 1999 International Workshop for a Classification of Periodontal Diseases and Conditions. Papers. Oak Brook, Illinois, October 30-November 2, 1999. Ann Periodontol 1999;4:i, 1-112.
28. Handfield M, Mans JJ, Zheng G, et al. Distinct transcriptional profiles characterize oral epithelium-microbiota interactions. Cell Microbiol 2005;7:811-823.
29. Hasegawa Y, Mans JJ, Mao S, et al. Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species. Infect Immun 2007;75:2540-2547.
30. Handfield M, Baker HV, Lamont RJ. Beyond good and evil in the oral cavity: Insights into host-microbe relationships derived from transcriptional profiling of gingival cells. J Dent Res 2008;87:203-223.
31. Ekuni D, Firth JD, Putnins EE. Regulation of epithelial cell growth factor receptor protein and gene expression using a rat periodontitis model. J Periodontal Res 2006;41:340-349.
32. Gijsbers K, Van Assche G, Joossens S, et al. CXCR1-binding chemokines in inflammatory bowel diseases: Down-regulated IL-8/CXCL8 production by leukocytes in Crohn's disease and selective GCP-2/CXCL6 expression in inflamed intestinal tissue. Eur J Immunol 2004;34:1992-2000.
33. Kubota T, Itagaki M, Hoshino C, et al. Altered gene expression levels of matrix metalloproteinases and their inhibitors in periodontitis-affected gingival tissue. J Periodontol 2008;79:166-173.