Modulation of arthritis in rats by Toxicodendron pubescens and its homeopathic dilutions

Homeopathy

Volumn 100, Issue 3, 2011, Pages 131-137

  Patil, Chandragouda Raosaheb ^a   Rambhade, Ashish Devidas ^a   Jadhav, Ramchandra Baburao ^a   Patil, Kalpesh Ramdas ^a   Dubey, Vishal Kumar ^a   Sonara, Bhavin Maheshkumar ^a   Toshniwal, Sanjay S ^b  

^a R C PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

^b Vidarbha Institute of Pharmacy   (India)

Author keywords

Adjuvant arthritis; Homeopathy; Inflammation; Rhus toxicodendron; Toxicodendron pubescens; Ultra dilutions

Indexed keywords

ANTIRHEUMATIC AGENT; C REACTIVE PROTEIN; DICLOFENAC; HERBACEOUS AGENT; HOMEOPATHIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE COUNT; FEMALE; JOINT RADIOGRAPHY; LEUKOCYTE COUNT; MALE; MEDICINAL PLANT; NONHUMAN; ORGAN WEIGHT; PAIN ASSESSMENT; PROTEIN BLOOD LEVEL; RAT; RHUS TOXICODENDRON; SPLEEN; SPLEEN WEIGHT; THYMUS; TOXICODENDRON PUBESCENS;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREUND'S ADJUVANT; HOMEOPATHY; MALE; PAIN; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; TOXICODENDRON;

EID: 79960620035     PISSN: 14754916     EISSN: 14764245     Source Type: Journal    
DOI: 10.1016/j.homp.2011.01.001     Document Type: Article

References (22)

1. Fisher P., Scott D.L. A randomized controlled trial of homeopathy in rheumatoid arthritis. Rheumatology 2001, 40:1052-1055.
2. Verma P., Vaid I. Encyclopedia of homeopathic pharmacopoeia 2002, B. Jain Publication, New Delhi, p. 781. 6th edn.
3. Xia Z., Miyakosh T., Yoshida T. Lipoxygenas-catalyzed polymerization of phenolic lipids suggests a new mechanism for allergic contact dermatitis induced by urushiol and its analogs. Biochem Biophys Res Commun 2004, 315:704-709.
4. Carvalho J., Santos A., Perazzo F., Cardoso L. In vivo study of the anti-inflammatory effect of the Rhus toxicodendron. Homeopathy 2007, 96:95-101.
5. Patil C., Gadekar A., Patel P., Rambhade A., Surana S., Gaushal M. Dual effect of Toxicodendron pubescens on carrageenan induced paw edema in rat. Homeopathy 2009, 98:88-91.
6. Patil C., Salunkhe P., Gaushal M., Gadekar A., Agrawal A., Surana S. Immunomodulatory activity of Toxicodendron pubescens in experimental models. Homeopathy 2009, 99:88-91.
7. Kumar V., Roy S. Protective effect of latex of Calotropis procera in Freund's complete adjuvant induced monoarthritis. Phytother Res 2009, 23:1-5.
8. Singh B., Bani S., Gupta D., Chandan B., Kaul A. Anti-inflammatory activity of 'TAF' an active fraction from the plant Barleria prionitis Linn. J Ethanopharmacol 2003, 85:187-193.
9. Bush K., Kirkham B., Walker J. The κ-opioid agonist, asimadoline, alters cytokine gene expression in adjuvant arthritis. Rheumatology 2001, 40:1013-1021.
10. Caceres I., Holly J., Priego T., Martin A., Calderon A., Villanua M. Arthritis-induced increase in serum levels of IGF-binding protein-3 in rats is secondary to the decrease in its proteolytic activity. J Endocrinol 2002, 173:357-364.
11. Kumar V., Roy S., Sehgal R., Padhy B. A comparative study on the efficacy of rofecoxib in monoarticular arthritis induced by latex of Calotropis procera and Freund's complete adjuvant. Inflammopharmacology 2006, 14:17-21.
12. Patil K.R., Patil C.R., Jadhav R.B., Mahajan V.K., Patil P.R., Gaikwad P.S. Anti-arthritic activity of bartogenic acid isolated from fruits of Barringtonia racemosa. Evidence Based Complementary and Alternative Medicine (eCAM) 2009, 10.1093/ecam/nep148.
13. Conway J., Wakefield J., Brown R., Marron B., Sekut L., Stimpson S. Inhibition of cartilage and bone destruction in adjuvant arthritis in the rat by a matrix metalloproteinase inhibitor. J Exp Med 1995, 182:449-457.
14. Escandell J., Recio M., Manez S., Giner R., Cerda-Nicolas M., Rios J. Cucurbitacin R reduces the inflammation and bone damage associated with adjuvant arthritis in Lewis rats by suppression of tumor necrosis factor-α in T lymphocytes and macrophages. JPET 2007, 320:581-590.
15. Laird J.M., Carter A.J., Grauert M., Cervero F. Analgesic activity of a novel use-dependent sodium channel blocker, crobenetine, in mono-arthritic rats. Br J Pharmacol 2001, 134:1742-1748.
16. Yu Y., Xiong Z., Lv Y., Qian Y., Jiang S., Tian Y. In vivo evaluation of early disease progression by X-ray phase-contrast imaging in the adjuvant-induced arthritic rat. Skeletal Radiol 2006, 35:156-164.
17. Hamada T., Arima N., Shindo M., Sugama K., Sasaguri Y. Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase inhibitor. Br J Pharmacol 2000, 131:1513-1520.
18. Hu F., Hepburn H., Yinghua L., Chen M., Radloff S., Daya S. Effect of ethanol and water extract of propolis (bee glue) on acute inflammatory animal models. J Ethanopharmacol 2005, 100:276-283.
19. Raiss R., Bartlett R. Antiarthrotic and immunmodulatory activity. Drug discovery and evaluation: pharmacological assays 2002, 775-820. Springer, New York, Chap I. 2nd edn. H. Gerhard Vogel (Ed.).
20. Ling S., Jamali F. Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies. DMD 2005, 33:579-586.
21. Beck A., Krischak G., Sorg T., et al. Influence of diclofenac (group of nonsteroidal anti-inflammatory drugs) on fracture healing. Arch Orthop Trauma Surg 2003, 123(7):327-332.
22. Patil K., Suryavashi J. Effect of Celastrus paniculatus wild seed on adjuvant induced arthritis in rats. Phcog Mag 2007, 3(11):177-181.