-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group.
-
The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993; 72: 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
2
-
-
2342598416
-
Experimental therapeutics in transgenic mouse models of Huntington's disease
-
Beal MF, Ferrante RJ. Experimental therapeutics in transgenic mouse models of Huntington's disease. Nat Rev Neurosci 2004; 5: 373-384.
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 373-384
-
-
Beal, M.F.1
Ferrante, R.J.2
-
4
-
-
30344476118
-
Pharmaceutical, cellular and genetic therapies for Huntington's disease
-
Handley OJ, Naji JJ, Dunnett SB, Rosser AE. Pharmaceutical, cellular and genetic therapies for Huntington's disease. Clin Sci 2006; 110: 73-88.
-
(2006)
Clin Sci
, vol.110
, pp. 73-88
-
-
Handley, O.J.1
Naji, J.J.2
Dunnett, S.B.3
Rosser, A.E.4
-
5
-
-
67349122746
-
Small molecule drug discovery for Huntington's Disease
-
Fecke W, Gianfriddo M, Gaviraghi G, et al. Small molecule drug discovery for Huntington's Disease. Drug Discov Today 2009; 14: 453-464.
-
(2009)
Drug Discov Today
, vol.14
, pp. 453-464
-
-
Fecke, W.1
Gianfriddo, M.2
Gaviraghi, G.3
-
6
-
-
60549103857
-
The R6 lines of transgenic mice: a model for screening new therapies for Huntington's disease
-
Gil JM, Rego AC. The R6 lines of transgenic mice: a model for screening new therapies for Huntington's disease. Brain Res Rev 2009; 59: 410-431.
-
(2009)
Brain Res Rev
, vol.59
, pp. 410-431
-
-
Gil, J.M.1
Rego, A.C.2
-
7
-
-
70049091196
-
Therapeutic interventions for disease progression in Huntington's disease
-
Mestre T, Ferreira J, Coelho MM, et al. Therapeutic interventions for disease progression in Huntington's disease. Cochrane Database Syst Rev 2009; 8: CD006455.
-
(2009)
Cochrane Database Syst Rev
, vol.8
-
-
Mestre, T.1
Ferreira, J.2
Coelho, M.M.3
-
8
-
-
45549085845
-
Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease
-
Bohanna I, Georgiou-Karistianis N, Hannan AJ, Egan GF. Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease. Brain Res Rev 2008; 58: 209-225.
-
(2008)
Brain Res Rev
, vol.58
, pp. 209-225
-
-
Bohanna, I.1
Georgiou-Karistianis, N.2
Hannan, A.J.3
Egan, G.F.4
-
9
-
-
41249101172
-
Neuroprotection for Huntington's disease: ready, set, slow
-
Hersch SM, Rosas HD. Neuroprotection for Huntington's disease: ready, set, slow. Neurotherapeutics 2008; 5: 226-236.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 226-236
-
-
Hersch, S.M.1
Rosas, H.D.2
-
10
-
-
68249111127
-
Biomarkers to predict and track diseases
-
Paulsen JS. Biomarkers to predict and track diseases. Lancet Neurol 2009; 8: 776-777.
-
(2009)
Lancet Neurol
, vol.8
, pp. 776-777
-
-
Paulsen, J.S.1
-
11
-
-
33847607138
-
Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease
-
Aylward EH. Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease. Brain Res Bull 2007; 72: 152-158.
-
(2007)
Brain Res Bull
, vol.72
, pp. 152-158
-
-
Aylward, E.H.1
-
12
-
-
0031037349
-
Longitudinal change in basal ganglia volume in patients with Huntington's disease
-
Aylward E, Li Q, Stine O, et al. Longitudinal change in basal ganglia volume in patients with Huntington's disease. Neurology 1997; 48: 394-399.
-
(1997)
Neurology
, vol.48
, pp. 394-399
-
-
Aylward, E.1
Li, Q.2
Stine, O.3
-
13
-
-
3242659833
-
Onset and rate of striatal atrophy in preclinical Huntington disease
-
Aylward EH, Sparks BF, Field KM, et al. Onset and rate of striatal atrophy in preclinical Huntington disease. Neurology 2004; 63: 66-72.
-
(2004)
Neurology
, vol.63
, pp. 66-72
-
-
Aylward, E.H.1
Sparks, B.F.2
Field, K.M.3
-
14
-
-
67651061155
-
Automated quantification of caudate atrophy by local registration of serial MRI: evaluation and application in Huntington's disease
-
Hobbs NZ, Henley SMD, Wild EJ, et al. Automated quantification of caudate atrophy by local registration of serial MRI: evaluation and application in Huntington's disease. Neuroimage 2009; 47: 1659-1665.
-
(2009)
Neuroimage
, vol.47
, pp. 1659-1665
-
-
Hobbs, N.Z.1
Henley, S.M.D.2
Wild, E.J.3
-
15
-
-
17644369971
-
Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study
-
Kipps CM, Duggins AJ, Mahant N, et al. Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study. J Neurol Neurosurg Psychiatr 2005; 76: 650-655.
-
(2005)
J Neurol Neurosurg Psychiatr
, vol.76
, pp. 650-655
-
-
Kipps, C.M.1
Duggins, A.J.2
Mahant, N.3
-
16
-
-
24644479046
-
Regional cortical thinning in preclinical Huntington disease and its relationship to cognition
-
Rosas HD, Hevelone ND, Zaleta AK, et al. Regional cortical thinning in preclinical Huntington disease and its relationship to cognition. Neurology 2005; 65: 745-747.
-
(2005)
Neurology
, vol.65
, pp. 745-747
-
-
Rosas, H.D.1
Hevelone, N.D.2
Zaleta, A.K.3
-
17
-
-
0036345704
-
The distribution of structural neuropathology in pre-clinical Huntington's disease
-
Thieben MJ, Duggins AJ, Good CD, et al. The distribution of structural neuropathology in pre-clinical Huntington's disease. Brain 2002; 125: 1815-1828.
-
(2002)
Brain
, vol.125
, pp. 1815-1828
-
-
Thieben, M.J.1
Duggins, A.J.2
Good, C.D.3
-
18
-
-
77950935234
-
Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study
-
Stoffers D, Sheldon S, Kuperman JM, et al. Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study. Neurology 2010; 74: 1208-1216.
-
(2010)
Neurology
, vol.74
, pp. 1208-1216
-
-
Stoffers, D.1
Sheldon, S.2
Kuperman, J.M.3
-
19
-
-
33747777842
-
Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease
-
Ciarmiello A, Cannella M, Lastoria S, et al. Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease. J Nucl Med 2006; 47: 215-222.
-
(2006)
J Nucl Med
, vol.47
, pp. 215-222
-
-
Ciarmiello, A.1
Cannella, M.2
Lastoria, S.3
-
20
-
-
60349114059
-
Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease
-
Squitieri F, Cannella M, Simonelli M, et al. Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease. CNS Neurosci Ther 2009; 15: 1-11.
-
(2009)
CNS Neurosci Ther
, vol.15
, pp. 1-11
-
-
Squitieri, F.1
Cannella, M.2
Simonelli, M.3
-
21
-
-
62049085680
-
Longitudinal diffusion tensor imaging in Huntington's disease
-
Weaver KE, Richards TL, Liang O, et al. Longitudinal diffusion tensor imaging in Huntington's disease. Exp Neurol 2009.
-
(2009)
Exp Neurol
-
-
Weaver, K.E.1
Richards, T.L.2
Liang, O.3
-
23
-
-
0036742197
-
Accurate, robust, and automated longitudinal and cross-sectional brain change analysis
-
Smith S, Zhang Y, Jenkinson M, et al. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 2002; 17: 479-489.
-
(2002)
Neuroimage
, vol.17
, pp. 479-489
-
-
Smith, S.1
Zhang, Y.2
Jenkinson, M.3
-
24
-
-
0016823810
-
"Mini-mental state." A practical method for grading the cognitive state of patients for the clinician
-
Folstein M, Folstein S, McHugh P. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
-
(1975)
J Psychiatr Res
, vol.12
, pp. 189-198
-
-
Folstein, M.1
Folstein, S.2
McHugh, P.3
-
25
-
-
85009332113
-
Unified Huntington's Disease Rating Scale: reliability and consistency
-
The Huntington's Study Group.
-
The Huntington's Study Group. Unified Huntington's Disease Rating Scale: reliability and consistency. Mov Disord 1996; 11: 136-142.
-
(1996)
Mov Disord
, vol.11
, pp. 136-142
-
-
-
26
-
-
0030447557
-
Basal ganglia volume and proximity to onset in presymptomatic Huntington disease
-
Aylward EH, Codori AM, Barta PE, et al. Basal ganglia volume and proximity to onset in presymptomatic Huntington disease. Arch Neurol 1996; 53: 1293-1296.
-
(1996)
Arch Neurol
, vol.53
, pp. 1293-1296
-
-
Aylward, E.H.1
Codori, A.M.2
Barta, P.E.3
-
27
-
-
1842477303
-
A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length
-
Langbehn DR, Brinkman RR, Falush D, et al. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clin Genet 2004; 65: 267-277.
-
(2004)
Clin Genet
, vol.65
, pp. 267-277
-
-
Langbehn, D.R.1
Brinkman, R.R.2
Falush, D.3
-
28
-
-
7044260964
-
Advances in functional and structural MR image analysis and implementation as FSL
-
Smith S, Jenkinson M, Woolrich M, et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004; 23( Suppl 1): S208-S219.
-
(2004)
Neuroimage
, vol.23
, Issue.SUPPL. 1
-
-
Smith, S.1
Jenkinson, M.2
Woolrich, M.3
-
30
-
-
0036828879
-
Fast robust automated brain extraction
-
Smith S. Fast robust automated brain extraction. Hum Brain Mapp 2002; 17: 143-155.
-
(2002)
Hum Brain Mapp
, vol.17
, pp. 143-155
-
-
Smith, S.1
-
31
-
-
0036425968
-
Improved optimization for the robust and accurate linear registration and motion correction of brain images
-
Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17: 825-841.
-
(2002)
Neuroimage
, vol.17
, pp. 825-841
-
-
Jenkinson, M.1
Bannister, P.2
Brady, M.3
Smith, S.4
-
32
-
-
0035384136
-
A global optimisation method for robust affine registration of brain images
-
Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal 2001; 5: 143-156.
-
(2001)
Med Image Anal
, vol.5
, pp. 143-156
-
-
Jenkinson, M.1
Smith, S.2
-
33
-
-
0034745001
-
Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm
-
Zhang Y, Brady M, Smith S. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging 2001; 20: 45-57.
-
(2001)
IEEE Trans Med Imaging
, vol.20
, pp. 45-57
-
-
Zhang, Y.1
Brady, M.2
Smith, S.3
-
34
-
-
84873091941
-
-
Extending SIENA for a multi-subject statistical analysis of sample-specific cerebral edge shifts: substantiation of early brain regeneration through abstinence from alcoholism. Tenth International Conference on Functional Mapping of the Human Brain
-
Bartsch AJ, Bendszus N, De Stefano N, et al. Extending SIENA for a multi-subject statistical analysis of sample-specific cerebral edge shifts: substantiation of early brain regeneration through abstinence from alcoholism. Tenth International Conference on Functional Mapping of the Human Brain, 2004.
-
(2004)
-
-
Bartsch, A.J.1
Bendszus, N.2
De Stefano, N.3
-
35
-
-
77950530012
-
Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals
-
Hua X, Lee S, Hibar DP, et al. Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals. Neuroimage 2010; 51: 63-75.
-
(2010)
Neuroimage
, vol.51
, pp. 63-75
-
-
Hua, X.1
Lee, S.2
Hibar, D.P.3
-
36
-
-
0036136472
-
Nonparametric permutation tests for functional neuroimaging: a primer with examples
-
Nichols TE, Holmes AP. Nonparametric permutation tests for functional neuroimaging: a primer with examples. Hum Brain Mapp 2002; 15: 1-25.
-
(2002)
Hum Brain Mapp
, vol.15
, pp. 1-25
-
-
Nichols, T.E.1
Holmes, A.P.2
-
37
-
-
0031975912
-
Subtle involuntary movements are not reliable indicators of incipient Huntington's disease
-
de Boo G, Tibben A, Hermans J, Maat A, Roos RA. Subtle involuntary movements are not reliable indicators of incipient Huntington's disease. Mov Disord 1998; 13: 96-99.
-
(1998)
Mov Disord
, vol.13
, pp. 96-99
-
-
de Boo, G.1
Tibben, A.2
Hermans, J.3
Maat, A.4
Roos, R.A.5
-
38
-
-
1942505886
-
Measurement error of two different techniques for brain atrophy assessment in multiple sclerosis
-
Sormani M, Rovaris M, Valsasina P, Wolinsky J, Comi G, Filippi M. Measurement error of two different techniques for brain atrophy assessment in multiple sclerosis. Neurology 2004; 62: 1432-1434.
-
(2004)
Neurology
, vol.62
, pp. 1432-1434
-
-
Sormani, M.1
Rovaris, M.2
Valsasina, P.3
Wolinsky, J.4
Comi, G.5
Filippi, M.6
-
39
-
-
77953537855
-
Striatal and white matter predictors of estimated diagnosis for Huntington disease
-
Paulsen JS, Nopoulos PC, Aylward E, et al. Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res Bull 2010.
-
(2010)
Brain Res Bull
-
-
Paulsen, J.S.1
Nopoulos, P.C.2
Aylward, E.3
-
41
-
-
34648827423
-
Morphology of the cerebral cortex in preclinical Huntington's disease
-
Nopoulos P, Magnotta V, Mikos A, Paulson H, Andreasen N, Paulsen J. Morphology of the cerebral cortex in preclinical Huntington's disease. Am J Psychiatry 2007; 164: 1428-1434.
-
(2007)
Am J Psychiatry
, vol.164
, pp. 1428-1434
-
-
Nopoulos, P.1
Magnotta, V.2
Mikos, A.3
Paulson, H.4
Andreasen, N.5
Paulsen, J.6
-
42
-
-
77349122826
-
CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches
-
Langbehn DR, Hayden MR, Paulsen JS, Group P-HIotHS. CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches. Am J Med Genet B Neuropsychiatr Genet 2010; 153B: 397-408.
-
(2010)
Am J Med Genet B Neuropsychiatr Genet
, vol.153 B
, pp. 397-408
-
-
Langbehn, D.R.1
Hayden, M.R.2
Paulsen, J.S.3
Group, P.-H.4
|