Basal ganglia volume and proximity to onset in presymptomatic Huntington disease

Archives of Neurology

Volumn 53, Issue 12, 1996, Pages 1293-1296

  Aylward, Elizabeth H ^a   Codori, Ann Marie ^a   Barta, Patrick E ^a   Pearlson, Godfrey D ^a   Harris, Gordon J ^b   Brandt, Jason ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRINUCLEOTIDE;

ADULT; ARTICLE; BASAL GANGLION; BRAIN ATROPHY; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GLOBUS PALLIDUS; HUMAN; HUNTINGTON CHOREA; MALE; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PUTAMEN; TRINUCLEOTIDE REPEAT;

EID: 0030447557     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.1996.00550120105023     Document Type: Article

References (9)

1. Meynert T. Diskussion zu fritsch. Psychiatr Centrablatt. 1877;47:7.
2. Harris GJ, Pearlson GD, Peyser GE, et al. Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's disease. Ann Neurol. 1992;31:69-75.
3. Vonsattel J, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP. Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol. 1985;44:559-577.
4. Carrasco LH, Mukherji CS. Atrophy of corpus striatum in normal male at risk of Huntington's chorea. Lancet. 1968;1:1388-1389.
5. HD Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell. 1993;72:971-983.
6. Gusella JF, Wexler NS, Conneally PM, et al. A polymorphic DNA marker genetically linked to Huntington's disease. Nature. 1983;306:234-238.
7. MacDonald ME, Haines JL, Zimmer M, et al. Recombination events suggest potential sites for the Huntington's disease gene. Neuron. 1989;3:183-190.
8. Aylward EH, Brandt J, Codori AM, Mangus RS, Barta PE, Harris GJ. Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons. Neurology. 1994;44:823-828.
9. Folstein SE, Jensen B, Leigh RJ, Folstein M. The measurement of abnormal movement: methods developed for Huritington's disease. Neurobehav Toxicol Teratol. 1983;5:605-609.