-
1
-
-
0034725986
-
Histological analysis of indirect somatic embryogenesis in the Marsh clubmoss Lycopodiella imundata (L.) Holub (Pteridophytes)
-
Atmane N., Blervacq A.S., Michaux-Ferriere N., and Vasseur J. Histological analysis of indirect somatic embryogenesis in the Marsh clubmoss Lycopodiella imundata (L.) Holub (Pteridophytes). Plant Sci. 156 (2000) 159-167
-
(2000)
Plant Sci.
, vol.156
, pp. 159-167
-
-
Atmane, N.1
Blervacq, A.S.2
Michaux-Ferriere, N.3
Vasseur, J.4
-
2
-
-
45649085601
-
-
Capancioni, S., Pfefferlé, F., Burgi, N., Bardet, M.-A., Bauduin, L., Charbon, S., Ménétrey, A., Nicolas, V., Simonin, M.-P., Tamchès, E., Scalfaro, P., Porchet, H., Garrouste, P., 2006. Preparation of a sustained-release implant of the acetylcholinesterase inhibitor ZT-1 by Hot-Melt Extrusion (HME) and evaluation in rats. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Debiopharm, Geneva, Switzerland.
-
Capancioni, S., Pfefferlé, F., Burgi, N., Bardet, M.-A., Bauduin, L., Charbon, S., Ménétrey, A., Nicolas, V., Simonin, M.-P., Tamchès, E., Scalfaro, P., Porchet, H., Garrouste, P., 2006. Preparation of a sustained-release implant of the acetylcholinesterase inhibitor ZT-1 by Hot-Melt Extrusion (HME) and evaluation in rats. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Debiopharm, Geneva, Switzerland.
-
-
-
-
3
-
-
45649084811
-
-
Csajka, C., Buclin, T., Nicolas, V., Grosgurin, P., Porchet, H., Scalfaro, P., Biollaz, J., Tamchès, E., 2006. Population pharmacokinetics of ZT-1 and its active metabolite huperzine a after intravenous, oral and subcutaneous administration in healthy volunteers. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Debiopharm, Geneva, Switzerland.
-
Csajka, C., Buclin, T., Nicolas, V., Grosgurin, P., Porchet, H., Scalfaro, P., Biollaz, J., Tamchès, E., 2006. Population pharmacokinetics of ZT-1 and its active metabolite huperzine a after intravenous, oral and subcutaneous administration in healthy volunteers. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Debiopharm, Geneva, Switzerland.
-
-
-
-
4
-
-
11144309108
-
Effect of growth regulators on Huperzia lucidulum explants in vitro
-
Dwyer T., and Waegel A.S. Effect of growth regulators on Huperzia lucidulum explants in vitro. Acta Hort. 631 (2004) 181-185
-
(2004)
Acta Hort.
, vol.631
, pp. 181-185
-
-
Dwyer, T.1
Waegel, A.S.2
-
5
-
-
0040847312
-
Gametophytes of Lycopodium as grown in vitro
-
Freeberg J.A., and Wetmore R.H. Gametophytes of Lycopodium as grown in vitro. Phytomorphology 7 (1957) 204-217
-
(1957)
Phytomorphology
, vol.7
, pp. 204-217
-
-
Freeberg, J.A.1
Wetmore, R.H.2
-
6
-
-
0142035366
-
The Lycopsida - a study in development
-
Freeberg J.A., and Wetmore R.H. The Lycopsida - a study in development. Phytomorphology 17 (1967) 78-91
-
(1967)
Phytomorphology
, vol.17
, pp. 78-91
-
-
Freeberg, J.A.1
Wetmore, R.H.2
-
7
-
-
2342501400
-
Galanthamine from snowdrop - the development of a modern drug against Alzheimer's disease from local Caucasian knowledge
-
Heinrich M., and Lee Teoh H. Galanthamine from snowdrop - the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. J. Ethnopharmacol. 92 (2004) 147-162
-
(2004)
J. Ethnopharmacol.
, vol.92
, pp. 147-162
-
-
Heinrich, M.1
Lee Teoh, H.2
-
8
-
-
0040444974
-
Formation of ubiquinone by tobacco plant cells in suspension culture
-
Ikeda T., Matsumoto T., and Noguchi M. Formation of ubiquinone by tobacco plant cells in suspension culture. Phytochemistry 15 (1976) 568-569
-
(1976)
Phytochemistry
, vol.15
, pp. 568-569
-
-
Ikeda, T.1
Matsumoto, T.2
Noguchi, M.3
-
9
-
-
0141953955
-
Progress in clinical, pharmacological, chemical and structural biological studies of huperzine A: a drug of traditional Chinese medicine origin for the treatment of Alzheimer's disease
-
Jiang H., Luo X., and Bai D. Progress in clinical, pharmacological, chemical and structural biological studies of huperzine A: a drug of traditional Chinese medicine origin for the treatment of Alzheimer's disease. Curr. Med. Chem. 10 (2003) 2231-2252
-
(2003)
Curr. Med. Chem.
, vol.10
, pp. 2231-2252
-
-
Jiang, H.1
Luo, X.2
Bai, D.3
-
10
-
-
0000274177
-
Study on the chemistry of huperzine-A and huperzine-B
-
Liu J.S., Yu C.M., Zhou Y.Z., Han Y.Y., Wu F.W., Qi B.F., and Zhu Y.L. Study on the chemistry of huperzine-A and huperzine-B. Acta Chim. Sin. 44 (1986) 1035-1040
-
(1986)
Acta Chim. Sin.
, vol.44
, pp. 1035-1040
-
-
Liu, J.S.1
Yu, C.M.2
Zhou, Y.Z.3
Han, Y.Y.4
Wu, F.W.5
Qi, B.F.6
Zhu, Y.L.7
-
11
-
-
84922342912
-
The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity
-
Liu J.S., Zhu Y.L., Yu C.M., Zhou Y.Z., Han Y.Y., Wu F.W., and Qi B.F. The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity. Can. J. Chem. 64 (1986) 837-839
-
(1986)
Can. J. Chem.
, vol.64
, pp. 837-839
-
-
Liu, J.S.1
Zhu, Y.L.2
Yu, C.M.3
Zhou, Y.Z.4
Han, Y.Y.5
Wu, F.W.6
Qi, B.F.7
-
12
-
-
11144328091
-
The Lycopodium alkaloids
-
Ma X., and Gang D.R. The Lycopodium alkaloids. Nat. Prod. Rep. 21 (2004) 752-772
-
(2004)
Nat. Prod. Rep.
, vol.21
, pp. 752-772
-
-
Ma, X.1
Gang, D.R.2
-
13
-
-
0031666920
-
Alkaloid patterns in Huperzia and some related genera of Lycopodiaceae sensu lato occurring in China and their contribution to classification
-
Ma X.-Q., Jiang S.-H., and Zhu D.-Y. Alkaloid patterns in Huperzia and some related genera of Lycopodiaceae sensu lato occurring in China and their contribution to classification. Biochem. Systemat. Ecol. 26 (1998) 723-728
-
(1998)
Biochem. Systemat. Ecol.
, vol.26
, pp. 723-728
-
-
Ma, X.-Q.1
Jiang, S.-H.2
Zhu, D.-Y.3
-
14
-
-
14644404923
-
Is there a better source of huperzine A than Huperzia serrata? Huperzine A content of Huperziaceae species in China
-
Ma X., Tan C., Zhu D., and Gang D.R. Is there a better source of huperzine A than Huperzia serrata? Huperzine A content of Huperziaceae species in China. J. Agric. Food Chem. 53 (2005) 1393-1398
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 1393-1398
-
-
Ma, X.1
Tan, C.2
Zhu, D.3
Gang, D.R.4
-
15
-
-
32544459593
-
A survey of potential huperzine A natural resources in China: the Huperziaceae
-
Ma X., Tan C., Zhu D., and Gang D.R. A survey of potential huperzine A natural resources in China: the Huperziaceae. J. Ethnopharmacol. 104 (2006) 54-67
-
(2006)
J. Ethnopharmacol.
, vol.104
, pp. 54-67
-
-
Ma, X.1
Tan, C.2
Zhu, D.3
Gang, D.R.4
-
16
-
-
34447578839
-
Huperzine A from Huperzia species-an ethnopharmacological review
-
Ma X., Tan C., Zhu D., Gang D.R., and Xiao P. Huperzine A from Huperzia species-an ethnopharmacological review. J. Ethnopharmacol. 113 (2007) 15-34
-
(2007)
J. Ethnopharmacol.
, vol.113
, pp. 15-34
-
-
Ma, X.1
Tan, C.2
Zhu, D.3
Gang, D.R.4
Xiao, P.5
-
17
-
-
45649084049
-
-
Misawa, M., 1994. Plant Tissue Culture: An Alternative for Production of Useful Metabolites. FAO Agricultural Services Bulletin No. 108. Food and Agriculture Organization of the United Nations, Rome.
-
Misawa, M., 1994. Plant Tissue Culture: An Alternative for Production of Useful Metabolites. FAO Agricultural Services Bulletin No. 108. Food and Agriculture Organization of the United Nations, Rome.
-
-
-
-
18
-
-
45649084657
-
-
Orgogozo, J. M., Tamchès, E., Wilkinson, D., Todorova Yancheva, S., Gagiano, C., Grosgurin, P., Porchet, H., Scalfaro, P., 2006. ZT-1 for the symptomatic treatment of mild to moderate Alzheimer's disease: preliminary results of a multicentre, randomised, double-blind placebo and active controlled phase II study. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Geneva, Switzerland.
-
Orgogozo, J. M., Tamchès, E., Wilkinson, D., Todorova Yancheva, S., Gagiano, C., Grosgurin, P., Porchet, H., Scalfaro, P., 2006. ZT-1 for the symptomatic treatment of mild to moderate Alzheimer's disease: preliminary results of a multicentre, randomised, double-blind placebo and active controlled phase II study. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Geneva, Switzerland.
-
-
-
-
19
-
-
0024518339
-
A total synthesis of (±)-huperzine A
-
Qian L., and Ji R. A total synthesis of (±)-huperzine A. Tetrahedron Lett. 30 (1989) 2089-2090
-
(1989)
Tetrahedron Lett.
, vol.30
, pp. 2089-2090
-
-
Qian, L.1
Ji, R.2
-
20
-
-
45649084712
-
-
Scalfaro, P., Nicolas, V., Simonin, M. P., Charbon, S., McCormick, M., Heimgartner, F., 2003. The Sustained Release of the Acetylcholinesterase Inhibitor ZT-1 Confers the Potential for a More Efficient Neuroprotection in Rats. Neurobiology of Aging Conference, New Orleans, USA.
-
Scalfaro, P., Nicolas, V., Simonin, M. P., Charbon, S., McCormick, M., Heimgartner, F., 2003. The Sustained Release of the Acetylcholinesterase Inhibitor ZT-1 Confers the Potential for a More Efficient Neuroprotection in Rats. Neurobiology of Aging Conference, New Orleans, USA.
-
-
-
-
21
-
-
45649083901
-
-
Scalfaro, P., Aeschlimann, C., Burger, F., Pruvost, A., Ménétrey, A., Nicolas, V., Porchet, H., Tamchès, E., 2006. The prolonged action of the acethylcholinesterase inhibitor ZT-1 after subcutaneous injections of sustained release implants in healty volunteers. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Geneva, Switzerland.
-
Scalfaro, P., Aeschlimann, C., Burger, F., Pruvost, A., Ménétrey, A., Nicolas, V., Porchet, H., Tamchès, E., 2006. The prolonged action of the acethylcholinesterase inhibitor ZT-1 after subcutaneous injections of sustained release implants in healty volunteers. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Geneva, Switzerland.
-
-
-
-
22
-
-
0036250657
-
The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances
-
Sloane P.D., Zimmerman S., Suchindran C., Reed P., Wang L., Boustani M., and Sudha S. The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances. Annu. Rev. Public Health 23 (2002) 213-231
-
(2002)
Annu. Rev. Public Health
, vol.23
, pp. 213-231
-
-
Sloane, P.D.1
Zimmerman, S.2
Suchindran, C.3
Reed, P.4
Wang, L.5
Boustani, M.6
Sudha, S.7
-
23
-
-
18844451532
-
Somatic embryogenesis and in vitro culture of Huperzia selago shoots as a potential source of huperzine A
-
Szypulaa W., Pietrosiuka A., Suchockib P., Olszowskaa O., Furmanowaa M., and Kazimierskaa O. Somatic embryogenesis and in vitro culture of Huperzia selago shoots as a potential source of huperzine A. Plant Sci. 168 (2005) 1443-1452
-
(2005)
Plant Sci.
, vol.168
, pp. 1443-1452
-
-
Szypulaa, W.1
Pietrosiuka, A.2
Suchockib, P.3
Olszowskaa, O.4
Furmanowaa, M.5
Kazimierskaa, O.6
-
25
-
-
0021763210
-
Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells
-
Tal B., Tamir I., Rokem J.S., and Goldberg I. Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells. Biochem. J. 219 (1984) 619-624
-
(1984)
Biochem. J.
, vol.219
, pp. 619-624
-
-
Tal, B.1
Tamir, I.2
Rokem, J.S.3
Goldberg, I.4
-
27
-
-
45649084153
-
-
Ushiyama, K., 1991. Plant Cell Culture in Japan. CMC Co. Ltd., Tokyo. CMC Co. Ltd., Tokyo.
-
Ushiyama, K., 1991. Plant Cell Culture in Japan. CMC Co. Ltd., Tokyo. CMC Co. Ltd., Tokyo.
-
-
-
-
28
-
-
45649085290
-
Fractional disinfection procedure for Huperzia lucidulum explants
-
Waegel A.S. Fractional disinfection procedure for Huperzia lucidulum explants. Hortscience 36 (2001) 583-584
-
(2001)
Hortscience
, vol.36
, pp. 583-584
-
-
Waegel, A.S.1
-
29
-
-
30144437522
-
Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine
-
Wang R., Yan H., and Tang X.C. Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol. Sin. 27 (2006) 1-26
-
(2006)
Acta Pharmacol. Sin.
, vol.27
, pp. 1-26
-
-
Wang, R.1
Yan, H.2
Tang, X.C.3
-
30
-
-
0039068942
-
Germination of spores of the Lycopodiaceae in axenic culture
-
Whittier D.P. Germination of spores of the Lycopodiaceae in axenic culture. Am. Fern J. 88 (1998) 106-113
-
(1998)
Am. Fern J.
, vol.88
, pp. 106-113
-
-
Whittier, D.P.1
-
31
-
-
34848834137
-
The gametophyte of Huperzia selago in culture
-
Whittier D.P., and Storchova H. The gametophyte of Huperzia selago in culture. Am. Fern J. 97 (2007) 149-154
-
(2007)
Am. Fern J.
, vol.97
, pp. 149-154
-
-
Whittier, D.P.1
Storchova, H.2
-
32
-
-
0002198050
-
Gametophytes of Lycopodium lucidulum form axenic culture
-
Whittier D.P., and Webster T.R. Gametophytes of Lycopodium lucidulum form axenic culture. Am. Fern J. 76 (1986) 48-55
-
(1986)
Am. Fern J.
, vol.76
, pp. 48-55
-
-
Whittier, D.P.1
Webster, T.R.2
-
33
-
-
34247134619
-
An estimate of the total worldwide societal costs of dementia in 2005
-
Wimo A., Winblad B., and Jönsson L. An estimate of the total worldwide societal costs of dementia in 2005. Alzheimer's Dementia 3 (2007) 81-91
-
(2007)
Alzheimer's Dementia
, vol.3
, pp. 81-91
-
-
Wimo, A.1
Winblad, B.2
Jönsson, L.3
-
34
-
-
0024338668
-
A practical synthesis of the Chinese nootropic agent huperzine-a - a possible lead in the treatment of Alzheimer's disease
-
Xia Y., and Kozikowski A.P. A practical synthesis of the Chinese nootropic agent huperzine-a - a possible lead in the treatment of Alzheimer's disease. J. Am. Chem. Soc. 111 (1989) 4116-4117
-
(1989)
J. Am. Chem. Soc.
, vol.111
, pp. 4116-4117
-
-
Xia, Y.1
Kozikowski, A.P.2
-
35
-
-
0043204247
-
The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective properties of interest in the treatment of Alzheimer's disease
-
Zangara A. The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective properties of interest in the treatment of Alzheimer's disease. Pharmacol. Biochem. Behav. 75 (2003) 675-686
-
(2003)
Pharmacol. Biochem. Behav.
, vol.75
, pp. 675-686
-
-
Zangara, A.1
-
36
-
-
45649083838
-
-
Zangara, A., Edgar, C., Wesnes, K., Scalfaro, P., Porchet, H., 2004. The effectiveness of ZT-1 and donepezil in reversing scopolamine-induced cognitive impariment in elderly volunteers. In: Proceedings of the XXIVth Collegium Internationale Neuro-psychopharmacologium (CINP) Congress. Paris, France.
-
Zangara, A., Edgar, C., Wesnes, K., Scalfaro, P., Porchet, H., 2004. The effectiveness of ZT-1 and donepezil in reversing scopolamine-induced cognitive impariment in elderly volunteers. In: Proceedings of the XXIVth Collegium Internationale Neuro-psychopharmacologium (CINP) Congress. Paris, France.
-
-
-
-
37
-
-
45649085473
-
-
Zangara, A., Edgar, C., Wesnes, K., Scalfaro, P., Porchet, H., 2006. Reversal of scopolamine-related deficits in cognitive functions by zt-1, a huperzine-a derivative. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Geneva, Switzerland.
-
Zangara, A., Edgar, C., Wesnes, K., Scalfaro, P., Porchet, H., 2006. Reversal of scopolamine-related deficits in cognitive functions by zt-1, a huperzine-a derivative. In: Proceedings of the Ninth International Geneva Springfield Symposium on Advanced Alzheimer Therapy. Geneva, Switzerland.
-
-
-
|