Design and synthesis of thienylpyridyl garlands as non-peptidic alpha helix mimetics and potential protein-protein interactions disruptors

Tetrahedron

Volumn 67, Issue 34, 2011, Pages 6145-6154

  De Giorgi, Marcella ^a,b   Voisin Chiret, Anne Sophie ^b   Sopková De Oliveira Santos, Jana ^b   Corbo, Filomena ^b   Franchini, Carlo ^a   Rault, Sylvain ^b  

^a UNIVERSITY OF BARI   (Italy)

^b CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE   (France)

Author keywords

Boron; Cross coupling; Palladium; Pyridine; Thiophene

Indexed keywords

2 CHLORO 5 [5 [5 [5 (6 CHLOROPYRIDIN 3 YL)THIOPHEN 2 YL]PYRIDIN 3 YL]THIOPHEN 2 YL]PYRIDINE; 2 FLUORO 5 [5 [5 [5 (6 FLUOROPYRIDIN 3 YL)THIOPHEN 2 YL]PYRIDIN 3 YL]THIOPHEN 2 YL]PYRIDINE; 2 METHOXY 5 [5 [5 [5 (6 METHOXYPYRIDIN 3 YL)THIOPHEN 2 YL]PYRIDIN 3 YL]THIOPHEN 2 YL]PYRIDINE; 3 [5 [5 [5 (PYRIDIN 3 YL)THIOPHEN 2 YL]PYRIDIN 3 YL]THIOPHEN 2 YL]PYRIDINE; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; PALLADIUM; PYRIDINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BROMINATION; CROSS COUPLING REACTION; DRUG DESIGN; DRUG SYNTHESIS; HALOGENATION; MOLECULARLY TARGETED THERAPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SUZUKI REACTION;

EID: 79960598849     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.06.074     Document Type: Article

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