Sustained release of BMP-2 in a lipid-based microtube vehicle

Acta Biomaterialia

Volumn 5, Issue 1, 2009, Pages 23-28

  Johnson, Mela R ^a   Lee, Hyun Jung ^a   Bellamkonda, Ravi V ^a   Guldberg, Robert E ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

BMP 2; Microtubes; Sustained release

Indexed keywords

BIOACTIVITY; CELL CULTURE; EFFICIENCY; LOADING; SELF ASSEMBLY; STEM CELLS; TISSUE ENGINEERING;

BMP-2; GROWTH FACTOR; LOADING EFFICIENCY; LOW LOADING; MICROTUBE; PROTEIN SOLUTION; RELEASE KINETICS; SELF-ASSEMBLY METHOD; SUSTAINED RELEASE; TISSUE ENGINEERING APPLICATIONS;

PHOSPHATASES;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; LIPID; ORGANIC SOLVENT;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONCENTRATION PROCESS; CONTROLLED STUDY; ENZYME ASSAY; HUMAN; HUMAN CELL; IMMUNOASSAY; IN VITRO STUDY; LOADING TEST; MESENCHYMAL STEM CELL; MICROTUBULE; NANOFABRICATION; PRIORITY JOURNAL; STAINING; SUSTAINED RELEASE PREPARATION; TISSUE ENGINEERING;

EID: 56349115299     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2008.09.001     Document Type: Article

References (34)

1. Hollinger J.O., Uludag H., and Winn S.R. Sustained release emphasizing recombinant human bone morphogenetic protein-2. Adv Drug Deliv Rev 31 3 (1998) 303-318
2. Oest M.E., et al. Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25 7 (2007) 941-950
3. Boontheekul T., and Mooney D.J. Protein-based signaling systems in tissue engineering. Curr Opin Biotechnol 14 15 (2003) 559-565
4. Lee S.J. Cytokine delivery and tissue engineering. Yonsei Med J (2000)
5. Tabata Y. Tissue regeneration based on growth factor release. Tissue Eng 9 Suppl. 1 (2003) S5-S15
6. Meilander N.J., et al. Lipid-based microtubular drug delivery vehicles. J Control Release 71 1 (2001) 141-152
7. Benoit D.S., and Anseth K.S. Heparin functionalized PEG gels that modulate protein adsorption for hMSC adhesion and differentiation. Acta Biomater 1 4 (2005) 461-470
8. Boden S.D. The ABCs of BMPs. Orthop Nurs 24 1 (2005) 49-52
9. Riley E.H., Lane J.M., Urist M.R., Lyons K.M., and Lieberman J.R. Bone morphogenetic protein-2: biology and applications. Clin Orthop Relat Res 324 (1996) 39-46
10. Riley E.H., et al. Bone morphogenetic protein-2: biology and applications. Clin Orthop Relat Res (1996)
11. Sakou T. Bone morphogenetic proteins: from basic studies to clinical approaches. Bone 22 6 (1998) 591-603
12. Wozney J.M. Bone morphogenetic proteins. Prog Growth Factor Res 1 4 (1989) 267-280
13. Lieberman J.R., Daluiski A., and Einhorn T.A. The role of growth factors in the repair of bone biology and clinical applications. J Bone Joint Surg (2002)
14. Tsiridis E., Upadhyay N., and Giannoudis P. Molecular aspects of fracture healing: which are the important molecules?. Injury 38 Suppl 1 (2007) S11-S25
15. Winn S.R., Uludag H., and Hollinger J.O. Sustained release emphasizing recombinant human bone morphogenetic protein-2. Adv Drug Deliv Rev 31 (1998) 303-318
16. Spargo B.J., et al. Controlled release of transforming growth factor-beta from lipid-based microcylinders. J Microencapsul (1995)
17. Jain A., et al. In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury. Biomaterials 27 3 (2006) 497-504
18. Yager P., and Schoen P.E. Formation of tubules by a polymerizable surfactant. Mol Cryst Liquid Cryst (1984)
19. Meilander N.J., et al. Sustained release of plasmid DNA using lipid microtubules and agarose hydrogel. J Control Release 88 2 (2003) 321-331
20. Carlson P.A., Gelb M.H., and Yager P. Zero-order interfacial enzymatic degradation of phospholipid tubules. Biophys J 73 1 (1997) 230-238
21. Yi F., Wu H., and Jia G.L. Formulation and characterization of poly (d, l-lactide-co-glycolide) nanoparticle containing.... J Clin Pharm Ther (2006)
22. Zambaux M.F., et al. Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method. J Control Release 50 1-3 (1998) 31-40
23. Chen X., and Ooi C.P. Hydrolytic degradation and drug release properties of ganciclovir-loaded biodegradable microspheres. Acta Biomater (2008)
24. Birnbaum D., and Brannon-Pepas L. Drug Deliv Sys Cancer Ther (2003) 390
25. Cohen H., et al. Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles. Gene Ther 7 22 (2000) 1896-1905
26. Dong Y., and Feng S.S. Poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy. Int J Pharm 342 1-2 (2007) 208-214
27. Datta N., et al. Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials (2005)
28. Lin H., et al. The effect of crosslinking heparin to demineralized bone matrix on mechanical strength and specific binding to human bone morphogenetic protein-2. Biomaterials 29 9 (2008) 1189-1197
29. Takada T., et al. Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. J Biol Chem 278 44 (2003) 43229-43235
30. Zhao B., et al. Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. J Biol Chem 281 32 (2006) 23246-23253
31. Hosseinkhani H., et al. Bone regeneration through controlled release of bone morphogenetic protein-2 from 3D tissue engineered nano-scaffold. J Control Release 117 3 (2007) 380-386
32. Jeon O., et al. Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery. Biochem Biophys Res Commun 369 2 (2008) 774-780
33. Yu X., and Bellamkonda R.V. Tissue-engineered scaffolds are effective alternatives to autografts for bridging peripheral nerve gaps. Tissue Eng 9 3 (2003) 421-430
34. Guo L., et al. Heterogeneous and anomalous diffusion inside lipid tubules. J Phys Chem B (2007) 25