GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 9, 2011, Pages 1080-1088

  Devi, Takhellambam S ^a   Singh, Lalit P ^a   Hosoya, Ken Ichi ^b   Terasaki, Tetsuya ^c  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TOYAMA   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

Cell cycle regulation; ECM adhesion molecule expression; GSK 3 CREB axis; IGF 1; Monolayer permeability

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN D1; FIBRONECTIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN KINASE B; SOMATOMEDIN C; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIUM; CELL ADHESION; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DIABETIC RETINOPATHY; DOWN REGULATION; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC TRANSFECTION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA CAPILLARY; UPREGULATION;

ANIMALS; BLOOD-RETINAL BARRIER; CELL ADHESION MOLECULES; CELL CYCLE; CELL LINE; CELL SURVIVAL; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; GLYCOGEN SYNTHASE KINASE 3; INSULIN-LIKE GROWTH FACTOR I; RATS; RETINA; SIGNAL TRANSDUCTION;

EID: 79960559106     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.04.007     Document Type: Article

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