Minimizing matrix effects while preserving throughput in LC-MS/MS bioanalysis

Bioanalysis

Volumn 3, Issue 14, 2011, Pages 1587-1601

  Ye, Zhengqi ^a   Tsao, Hong ^a   Gao, Hong ^a   Brummel, Christopher L ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ATORVASTATIN; CAFFEINE; CHLORAMPHENICOL; CHLORTALIDONE; FLUOXETINE; GLIPIZIDE; IBUPROFEN; METOPROLOL; MIDAZOLAM; PHOSPHOLIPID; PRAVASTATIN; QUINIDINE; TAMOXIFEN; TESTOSTERONE; TRIMETHOPRIM; VERAPAMIL;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STRUCTURE; FLOW RATE; HIGH THROUGHPUT SCREENING; HYDROPHOBICITY; IONIZATION; LIQUID CHROMATOGRAPHY; MATHEMATICAL ANALYSIS; MEDICAL RESEARCH; NONHUMAN; PRECIPITATION; RAT; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

ACETONITRILES; ANIMALS; CHROMATOGRAPHY, LIQUID; METHANOL; PHARMACEUTICAL PREPARATIONS; PHOSPHOLIPIDS; RATS; TANDEM MASS SPECTROMETRY;

EID: 79960502740     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.141     Document Type: Article

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