Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions

Journal of Zhejiang University: Science B

Volumn 12, Issue 7, 2011, Pages 534-544

  Zhao, Qin ^a   Liu, Zhi Dong ^a   Xue, Yong ^a   Wang, Jing Feng ^a   Li, Hui ^a   Tang, Qing Juan ^a   Wang, Yu Ming ^a   Dong, Ping ^a   Xue, Chang Hu ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Angiogenesis; Ds echinoside A (DSEA); Matrix metalloproteinase 9 (MMP 9); Metastasis; Nuclear factor B (NF B); Triterpene glycoside; Vascular endothelial growth factor (VEGF)

Indexed keywords

ANTINEOPLASTIC AGENT; DS ECHINOSIDE A; GELATINASE B; GLYCOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CHICK EMBRYO; DRUG MECHANISM; EMBRYO; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; NONHUMAN; PEARSONOTHURIA GRAEFFEI; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEA CUCUMBER; TUMOR VASCULARIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CHICK EMBRYO; ENDOTHELIAL CELLS; HEP G2 CELLS; HOLOTHURIN; HUMANS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NF-KAPPA B; SEA CUCUMBERS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

HOLOTHUROIDEA; PEARSONOTHURIA GRAEFFEI;

EID: 79960466765     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B1000217     Document Type: Article

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