Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells

FEBS Letters

Volumn 583, Issue 4, 2009, Pages 697-702

  Jin, Jun O ^a   Shastina, Valeria V ^a,b   Shin, Sung Won ^a   Xu, Qi ^a   Park, Joo In ^a   Rasskazov, Valery A ^b   Avilov, Sergey A ^b   Fedorov, Sergey N ^b   Stonik, Valentin A ^b   Kwak, Jong Young ^a  

^a Department of Biochemistry   (South Korea)

^b PACIFIC INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Apoptosis; Caspase; Frondoside A; Leukemia; Triterpene glycosides

Indexed keywords

AGLYCONE; CUCUMARIOSIDE A2 2; FRONDOSIDE A; GLYCOSIDE; MONOSACCHARIDE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; XYLOSE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; SEA CUCUMBER; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANNEXIN A5; APOPTOSIS; CASPASES; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GLYCOSIDES; HL-60 CELLS; HUMANS; LETHAL DOSE 50; LEUKEMIA; MOLECULAR STRUCTURE; SAPONINS; SEA CUCUMBERS; TIME FACTORS; TRITERPENES;

HOLOTHURIA; HOLOTHUROIDEA;

EID: 59849113018     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.01.010     Document Type: Article

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