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Volumn 59, Issue 1, 2011, Pages 81-89

Recurrent copy number gains of ACVR1 and corresponding transcript overexpression are associated with survival in head and neck squamous cell carcinomas

Author keywords

ACVR1; Chromosomal abnormalities; FISH; Head and neck cancer; Laryngeal carcinomas; Oral carcinomas; Pharyngeal carcinomas; QRT PCR

Indexed keywords

ACTIVIN A RECEPTOR TYPE 1; ACTIVIN RECEPTOR 1; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 79960462297     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2011.03885.x     Document Type: Article
Times cited : (5)

References (36)
  • 2
    • 35148821848 scopus 로고    scopus 로고
    • Aberrant expression of cortactin in head and neck squamous cell carcinoma cells is associated with enhanced cell proliferation and resistance to the epidermal growth factor receptor inhibitor gefitinib
    • Timpson P, Wilson AS, Lehrbach GM, Sutherland RL, Musgrove EA, Daly RJ. Aberrant expression of cortactin in head and neck squamous cell carcinoma cells is associated with enhanced cell proliferation and resistance to the epidermal growth factor receptor inhibitor gefitinib. Cancer Res. 2007; 67; 9304-9314.
    • (2007) Cancer Res. , vol.67 , pp. 9304-9314
    • Timpson, P.1    Wilson, A.S.2    Lehrbach, G.M.3    Sutherland, R.L.4    Musgrove, E.A.5    Daly, R.J.6
  • 4
    • 79960463769 scopus 로고    scopus 로고
    • Mitelman Database of Chromosome Aberrations in Cancer (). Mitelman F, Johansson B, Mertens F (eds). Available at: (accessed February 2009).
    • Mitelman Database of Chromosome Aberrations in Cancer (2009). Mitelman F, Johansson B, Mertens F (eds). Available at: (accessed February 2009).
    • (2009)
  • 5
    • 0034064708 scopus 로고    scopus 로고
    • Comparative genomic hybridization analysis detects frequent over-representation of DNA sequences at 3q, 7p, and 8q in head and neck carcinomas
    • Bérgamo NA, Rogatto SR, Poli-frederico RC et al. Comparative genomic hybridization analysis detects frequent over-representation of DNA sequences at 3q, 7p, and 8q in head and neck carcinomas. Cancer Genet. Cytogenet. 2000; 119; 48-55.
    • (2000) Cancer Genet. Cytogenet. , vol.119 , pp. 48-55
    • Bérgamo, N.A.1    Rogatto, S.R.2    Poli-frederico, R.C.3
  • 6
    • 12244289921 scopus 로고    scopus 로고
    • Classic and molecular cytogenetic analyses reveal chromosomal gains and losses correlated with survival in head and neck cancer patients
    • Bérgamo NA, da Silva Veiga LC, dos Reis PP et al. Classic and molecular cytogenetic analyses reveal chromosomal gains and losses correlated with survival in head and neck cancer patients. Clin. Cancer Res. 2005; 11; 621-631.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 621-631
    • Bérgamo, N.A.1    da Silva Veiga, L.C.2    dos Reis, P.P.3
  • 7
    • 2642673070 scopus 로고    scopus 로고
    • Genomic alterations associated with malignancy in head and neck cancer
    • Bockmühl U, Wolf G, Schmidt S et al. Genomic alterations associated with malignancy in head and neck cancer. Head Neck 1998; 20; 145-151.
    • (1998) Head Neck , vol.20 , pp. 145-151
    • Bockmühl, U.1    Wolf, G.2    Schmidt, S.3
  • 8
    • 0036456170 scopus 로고    scopus 로고
    • DNA ploidy and chromosomal alterations in head and neck squamous cell carcinoma
    • Bockmühl U, Peterson I. DNA ploidy and chromosomal alterations in head and neck squamous cell carcinoma. Virchows Arch. 2002; 441; 541-550.
    • (2002) Virchows Arch. , vol.441 , pp. 541-550
    • Bockmühl, U.1    Peterson, I.2
  • 9
    • 0031895154 scopus 로고    scopus 로고
    • DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies
    • Knuutila S, Bjorkqvist AM, Autio K et al. DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies. Am. J. Pathol. 1998; 152; 1107-1123.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1107-1123
    • Knuutila, S.1    Bjorkqvist, A.M.2    Autio, K.3
  • 10
    • 35848948207 scopus 로고    scopus 로고
    • Activin receptor-like kinase-2 inhibits activin signaling by blocking the binding of activin to its type II receptor
    • Renlund N, O'Neill FH, Zhang L, Sidis Y, Teixeira J. Activin receptor-like kinase-2 inhibits activin signaling by blocking the binding of activin to its type II receptor. J. Endocrinol. 2007; 195; 95-103.
    • (2007) J. Endocrinol. , vol.195 , pp. 95-103
    • Renlund, N.1    O'Neill, F.H.2    Zhang, L.3    Sidis, Y.4    Teixeira, J.5
  • 11
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-beta/Smad signaling system
    • Massagué J, Wotton D. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J. 2000; 19; 1745-1754.
    • (2000) EMBO J. , vol.19 , pp. 1745-1754
    • Massagué, J.1    Wotton, D.2
  • 14
    • 0032920835 scopus 로고    scopus 로고
    • Hemangioendothelioma of bone in a patient with a constitutional supernumerary marker
    • Rogatto SR, Rainho CA, Zhang ZM et al. Hemangioendothelioma of bone in a patient with a constitutional supernumerary marker. Cancer Genet. Cytogenet. 1999; 110; 23-27.
    • (1999) Cancer Genet. Cytogenet. , vol.110 , pp. 23-27
    • Rogatto, S.R.1    Rainho, C.A.2    Zhang, Z.M.3
  • 16
    • 42649138579 scopus 로고    scopus 로고
    • Evaluation of estrogen receptor alpha and beta and progesterone receptor expression and correlation with clinicopathologic factors and proliferative marker Ki-67 in breast cancers
    • Rosa FE, Caldeira JR, Felipes J et al. Evaluation of estrogen receptor alpha and beta and progesterone receptor expression and correlation with clinicopathologic factors and proliferative marker Ki-67 in breast cancers. Hum. Pathol. 2008; 39; 720-730.
    • (2008) Hum. Pathol. , vol.39 , pp. 720-730
    • Rosa, F.E.1    Caldeira, J.R.2    Felipes, J.3
  • 17
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
    • Bustin SA, Benes V, Garson JA et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 2009; 55; 611-622.
    • (2009) Clin. Chem. , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25; 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 2942529465 scopus 로고    scopus 로고
    • Can a genetic signature for metastatic head and neck squamous cell carcinoma be characterised by comparative genomic hybridisation?
    • Patmore HS, Ashman JN, Cawkwell L, MacDonald A, Stafford ND, Greenman J. Can a genetic signature for metastatic head and neck squamous cell carcinoma be characterised by comparative genomic hybridisation? Br. J. Cancer 2004; 90; 1976-1982.
    • (2004) Br. J. Cancer , vol.90 , pp. 1976-1982
    • Patmore, H.S.1    Ashman, J.N.2    Cawkwell, L.3    MacDonald, A.4    Stafford, N.D.5    Greenman, J.6
  • 20
    • 0032127379 scopus 로고    scopus 로고
    • Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32
    • Tapper J, Sarantaus L, Vahteristo P et al. Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32. Cancer Res. 1998; 58; 2715-2719.
    • (1998) Cancer Res. , vol.58 , pp. 2715-2719
    • Tapper, J.1    Sarantaus, L.2    Vahteristo, P.3
  • 21
    • 0345390860 scopus 로고    scopus 로고
    • Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the black and colored populations of South Africa
    • Du Plessis L, Dietzsch E, Van Gele M et al. Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the black and colored populations of South Africa. Cancer Res. 1999; 59; 1877-1883.
    • (1999) Cancer Res. , vol.59 , pp. 1877-1883
    • Du Plessis, L.1    Dietzsch, E.2    Van Gele, M.3
  • 22
    • 0034820339 scopus 로고    scopus 로고
    • Frequent increase of DNA copy number in the 2q24 chromosomal region and its association with a poor clinical outcome in hepatoblastoma: cytogenetic and comparative genomic hybridization analysis
    • Kumon K, Kobayashi H, Namiki T et al. Frequent increase of DNA copy number in the 2q24 chromosomal region and its association with a poor clinical outcome in hepatoblastoma: cytogenetic and comparative genomic hybridization analysis. Jpn. J. Cancer Res. 2001; 92; 854-862.
    • (2001) Jpn. J. Cancer Res. , vol.92 , pp. 854-862
    • Kumon, K.1    Kobayashi, H.2    Namiki, T.3
  • 23
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman GJ, Nicolás FJ, Callahan JF et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol. 2002; 62; 65-74.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolás, F.J.2    Callahan, J.F.3
  • 24
    • 0030829588 scopus 로고    scopus 로고
    • Apoptosis and carcinogenesis
    • Lyons SK, Clarke AR. Apoptosis and carcinogenesis. Br. Med. Bull. 1997; 53; 554-569.
    • (1997) Br. Med. Bull. , vol.53 , pp. 554-569
    • Lyons, S.K.1    Clarke, A.R.2
  • 25
    • 0034873386 scopus 로고    scopus 로고
    • The role of overexpressed HER2 in transformation
    • Neve RM, Lane HA, Hynes NE. The role of overexpressed HER2 in transformation. Ann. Oncol. 2001; 12; 9-13.
    • (2001) Ann. Oncol. , vol.12 , pp. 9-13
    • Neve, R.M.1    Lane, H.A.2    Hynes, N.E.3
  • 26
    • 0025271662 scopus 로고
    • Amplification of cellular oncogenes: a predictor of clinical outcome in human cancer
    • Schwab M, Amler LC. Amplification of cellular oncogenes: a predictor of clinical outcome in human cancer. Genes Chromosom. Cancer 1990; 1; 181-193.
    • (1990) Genes Chromosom. Cancer , vol.1 , pp. 181-193
    • Schwab, M.1    Amler, L.C.2
  • 27
    • 30144431670 scopus 로고    scopus 로고
    • Manifestation, mechanisms and mysteries of gene amplifications
    • Myllykangas S, Knuutila S. Manifestation, mechanisms and mysteries of gene amplifications. Cancer Lett. 2006; 232; 79-89.
    • (2006) Cancer Lett. , vol.232 , pp. 79-89
    • Myllykangas, S.1    Knuutila, S.2
  • 28
    • 77954043818 scopus 로고    scopus 로고
    • Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms
    • Jung B, Gomez J, Chau E et al. Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms. PLoS One 2009; 4; e8308.
    • (2009) PLoS One , vol.4
    • Jung, B.1    Gomez, J.2    Chau, E.3
  • 29
    • 0032213107 scopus 로고    scopus 로고
    • The role of activin type I receptors in activin A-induced growth arrest and apoptosis in mouse B-cell hybridoma cells
    • Hashimoto O, Yamato K, Koseki T et al. The role of activin type I receptors in activin A-induced growth arrest and apoptosis in mouse B-cell hybridoma cells. Cell. Signal. 1998; 10; 743-749.
    • (1998) Cell. Signal. , vol.10 , pp. 743-749
    • Hashimoto, O.1    Yamato, K.2    Koseki, T.3
  • 30
    • 34548705794 scopus 로고    scopus 로고
    • BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo
    • Buijs JT, Rentsch CA, van der Horst G et al. BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am. J. Pathol. 2007; 171; 1047-1057.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1047-1057
    • Buijs, J.T.1    Rentsch, C.A.2    van der Horst, G.3
  • 31
    • 36048973196 scopus 로고    scopus 로고
    • Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway
    • Craft CS, Romero D, Vary CP, Bergan RC. Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway. Oncogene 2007; 26; 7240-7250.
    • (2007) Oncogene , vol.26 , pp. 7240-7250
    • Craft, C.S.1    Romero, D.2    Vary, C.P.3    Bergan, R.C.4
  • 32
    • 33646271828 scopus 로고    scopus 로고
    • Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways
    • Yang S, Lim M, Pham LK et al. Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways. Cancer Res. 2006; 66; 4285-4290.
    • (2006) Cancer Res. , vol.66 , pp. 4285-4290
    • Yang, S.1    Lim, M.2    Pham, L.K.3
  • 33
    • 34547657084 scopus 로고    scopus 로고
    • Endogenous bone morphogenetic protein-7 controls the motility of prostate cancer cells through regulation of bone morphogenetic protein antagonists
    • Ye L, Lewis-Russell JM, Kynaston H, Jiang WG. Endogenous bone morphogenetic protein-7 controls the motility of prostate cancer cells through regulation of bone morphogenetic protein antagonists. J. Urol. 2007; 178; 1086-1091.
    • (2007) J. Urol. , vol.178 , pp. 1086-1091
    • Ye, L.1    Lewis-Russell, J.M.2    Kynaston, H.3    Jiang, W.G.4
  • 34
    • 57349117010 scopus 로고    scopus 로고
    • Identification of an invasion and tumor-suppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma
    • Wong VCL, Chan PL, Bernabeu C et al. Identification of an invasion and tumor-suppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma. Int. J. Cancer 2008; 123; 2816-2823.
    • (2008) Int. J. Cancer , vol.123 , pp. 2816-2823
    • Wong, V.C.L.1    Chan, P.L.2    Bernabeu, C.3
  • 35
    • 0036152351 scopus 로고    scopus 로고
    • Endoglin (CD105) expression in squamous cell carcinoma of the oral cavity
    • Schimming R, Marmé D. Endoglin (CD105) expression in squamous cell carcinoma of the oral cavity. Head Neck 2002; 24; 151-156.
    • (2002) Head Neck , vol.24 , pp. 151-156
    • Schimming, R.1    Marmé, D.2
  • 36
    • 33744739507 scopus 로고    scopus 로고
    • Endoglin (CD105) as a prognostic factor in head and neck squamous cell carcinoma
    • Kyzas PA, Agnantis NJ, Stefanou D. Endoglin (CD105) as a prognostic factor in head and neck squamous cell carcinoma. Virchows Arch. 2006; 448; 768-775.
    • (2006) Virchows Arch. , vol.448 , pp. 768-775
    • Kyzas, P.A.1    Agnantis, N.J.2    Stefanou, D.3


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