Expiratory flows and airway inflammation in elderly asthmatic patients

Respiratory Medicine

Volumn 105, Issue 9, 2011, Pages 1284-1289

  Ducharme, Marie Eve ^a   Prince, Philippe ^a   Hassan, Nesreen ^b   Nair, Parameswaran ^b   Boulet, Louis Philippe ^a  

^a LAVAL UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Airway inflammation; Elderly asthma; Induced sputum

Indexed keywords

CORTICOSTEROID;

ADULT; AGED; AIRWAY OBSTRUCTION; ARTICLE; ASTHMA; CONTROLLED STUDY; EXPIRATORY FLOW; FEMALE; FORCED EXPIRATORY VOLUME; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL COUNT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPUTUM ANALYSIS;

ADRENAL CORTEX HORMONES; ADULT; AGE FACTORS; AGED; ASTHMA; BRONCHITIS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LYMPHOCYTES; MACROPHAGES; MALE; MIDDLE AGED; NEUTROPHILS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SPUTUM;

EID: 79960452983     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2011.04.006     Document Type: Article

References (26)

1. P.G. Gibson, V.M. McDonald, and G.B. Marks Asthma in older adults Lancet 376 2010 803 813
2. S.S. Braman Asthma in the elderly Clin Geriatr Med 19 2003 57 75 (Pubitemid 36020195)
3. J.A. Krishman, S.Q. Davis, J.T. Charbeneau, F. Holguin, and E.T. Naureckas Hospitalizations for asthma in the elderly in the U.S. in 2000 and 2005 Am J Respir Crit Care Med 177 2008 A667 Ref Type: Generic
4. P. Lange, J. Parner, J. Vestbo, P. Schnohr, and G. Jensen A 15-year follow-up study of ventilatory function in adults with asthma N Engl J Med 339 1998 1194 1200
5. G.B. Marks, D.H. Yates, M. Sist, B. Ceyhan, C.M. De, D.M. Scott, and P.J. Barnes Respiratory sensation during bronchial challenge testing with methacholine, sodium metabisulphite, and adenosine monophosphate Thorax 51 1996 793 798 (Pubitemid 26274079)
6. M.J. Connolly, J.J. Crowley, N.B. Charan, C.P. Nielson, and R.E. Vestal Reduced subjective awareness of bronchoconstriction provoked by methacholine in elderly asthmatic and normal subjects as measured on a simple awareness scale Thorax 47 1992 410 413
7. S.E. Marsh, J. Travers, M. Weatherall, M.V. Williams, S. Aldington, P.M. Shirtcliffe, A.L. Hansell, M.R. Nowitz, A.A. McNaughton, J.B. Soriano, and R.W. Beasley Proportional classifications of COPD phenotypes Thorax 63 2008 761 767
8. K. Parameswaran, A.J. Hildreth, D. Chadha, N.P. Keaney, I.K. Taylor, and S.K. Bansal Asthma in the elderly: underperceived, underdiagnosed and undertreated; a community survey Respir Med 92 1998 573 577 (Pubitemid 28162174)
9. Y.J. Cho, and K.E. Lee Decreased glucocorticoid binding affinity to glucocorticoid receptor is important in the poor response to steroid therapy of older-aged patients with severe bronchial asthma Allergy Asthma Proc 24 2003 353 358 (Pubitemid 37414437)
10. Canadian Asthma Consensus Report L.P. Boulet, A. Becker, D. Berube, R. Beveridge, and P. Ernst Canadian asthma consensus group Can Med Assoc J 161 1999 S1 S61
11. A.R. Brody, and J.E. Craighead Cytoplasmic inclusions in pulmonary macrophages of cigarette smokers Lab Invest 32 1975 125 132
12. E. Pizzichini, M.M. Pizzichini, A. Efthimiadis, S. Evans, M.M. Morris, D. Squillace, G.J. Gleich, J. Dolovich, and F.E. Hargreave Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements Am J Respir Crit Care Med 154 1996 308 317 (Pubitemid 26269096)
13. J. Belda, R. Leigh, K. Parameswaran, P.M. O'Byrne, M.R. Sears, and F.E. Hargreave Induced sputum cell counts in healthy adults Am J Respir Crit Care Med 161 2000 475 478 (Pubitemid 30129455)
14. A. Spanevello, M. Confalonieri, F. Sulotto, F. Romano, G. Balzano, G.B. Migliori, A. Bianchi, and G. Michetti Induced sputum cellularity. Reference values and distribution in normal volunteers Am J Respir Crit Care Med 162 2000 1172 1174
15. C. Cassino, K.I. Berger, R.M. Goldring, R.G. Norman, S. Kammerman, C. Ciotoli, and J. Reibman Duration of asthma and physiologic outcomes in elderly nonsmokers Am J Respir Crit Care Med 162 2000 1423 1428
16. D.E. Shaw, M.A. Berry, B. Hargadon, S. McKenna, M.J. Shelley, R.H. Green, C.E. Brightling, A.J. Wardlaw, and I.D. Pavord Association between neutrophilic airway inflammation and airflow limitation in adults with asthma Chest 132 2007 1871 1875
17. S.M. Nyenhuis, E.A. Schwantes, M.D. Evans, and S.K. Mathur Airway neutrophil inflammatory phenotype in older subjects with asthma J Allergy Clin Immunol 2010
18. A.M. Vignola, N. Scichilone, J. Bousquet, G. Bonsignore, and V. Bellia Aging and asthma: pathophysiological mechanisms Allergy 58 2003 165 175 (Pubitemid 36609354)
19. S.A. Lonky, and J. McCarren Neutrophil enzymes in the lung: regulation of neutrophil elastase Am Rev Respir Dis 127 1983 S9 S15
20. R.A. Thomas, R.H. Green, C.E. Brightling, S.S. Birring, D. Parker, A.J. Wardlaw, and I.D. Pavord The influence of age on induced sputum differential cell counts in normal subjects Chest 126 2004 1811 1814 (Pubitemid 39643984)
21. D.C. Cowan, J.O. Cowan, R. Palmay, A. Williamson, and D.R. Taylor Effects of steroid therapy on inflammatory cell subtypes in asthma Thorax 65 2010 384 390
22. X. Zhang, E. Moilanen, and H. Kankaanranta Beclomethasone, budesonide and fluticasone propionate inhibit human neutrophil apoptosis Eur J Pharmacol 431 2001 365 371 (Pubitemid 33145416)
23. E.K. Verbeken, M. Cauberghs, I. Mertens, J. Clement, J.M. Lauweryns, and K.P. van de Woestijne The senile lung. Comparison with normal and emphysematous lungs. 2. Functional aspects Chest 101 1992 800 809
24. E.K. Verbeken, M. Cauberghs, I. Mertens, J. Clement, J.M. Lauweryns, and K.P. van de Woestijne The senile lung. Comparison with normal and emphysematous lungs. 1. Structural aspects Chest 101 1992 793 799
25. M.T. Al-Samri, A. Benedetti, D. Prefontaine, R. Olivenstein, C. Lemiere, P. Nair, J.G. Martin, and Q. Hamid Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: a prospective study using multiple samples J Allergy Clin Immunol 125 2010 1161 1163
26. F.E. Hargreave, and K. Parameswaran Asthma, COPD and bronchitis are just components of airway disease Eur Respir J 28 2006 264 267 (Pubitemid 44914223)