-
1
-
-
0038283161
-
Interleukin-10 therapy-review of a new approach
-
Asadullah, K., W. Sterry, and H. D. Volk. 2003. Interleukin-10 therapy-review of a new approach. Pharmacol. Rev. 55:241-269.
-
(2003)
Pharmacol. Rev.
, vol.55
, pp. 241-269
-
-
Asadullah, K.1
Sterry, W.2
Volk, H.D.3
-
2
-
-
70449528956
-
IL-10 signaling blockade controls murine West Nile virus infection
-
Bai, F., et al. 2009. IL-10 signaling blockade controls murine West Nile virus infection. PLoS Pathog. 5:e1000610.
-
(2009)
PLoS Pathog
, vol.5
-
-
Bai, F.1
-
3
-
-
0035914841
-
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
-
Belkaid, Y., et al. 2001. The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. 194: 1497-1506.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1497-1506
-
-
Belkaid, Y.1
-
4
-
-
31544476315
-
Coronavirus infection of the central nervous system: host-virus stand-off
-
Bergmann, C. C., T. E. Lane, and S. A. Stohlman. 2006. Coronavirus infection of the central nervous system: host-virus stand-off. Nat. Rev. Microbiol. 4:121-132.
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 121-132
-
-
Bergmann, C.C.1
Lane, T.E.2
Stohlman, S.A.3
-
5
-
-
33750499311
-
Interleukin-10 determines viral clearance or persistence in vivo
-
Brooks, D. G., et al. 2006. Interleukin-10 determines viral clearance or persistence in vivo. Nat. Med. 12:1301-1309.
-
(2006)
Nat. Med.
, vol.12
, pp. 1301-1309
-
-
Brooks, D.G.1
-
6
-
-
47249155734
-
Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice
-
Choi, J. J., et al. 2008. Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice. Clin. Exp. Immunol. 153:269-276.
-
(2008)
Clin. Exp. Immunol.
, vol.153
, pp. 269-276
-
-
Choi, J.J.1
-
7
-
-
0035869309
-
Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system
-
Croxford, J. L., M. Feldmann, Y. Chernajovsky, and D. Baker. 2001. Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system. J. Immunol. 166:4124-4130.
-
(2001)
J. Immunol.
, vol.166
, pp. 4124-4130
-
-
Croxford, J.L.1
Feldmann, M.2
Chernajovsky, Y.3
Baker, D.4
-
8
-
-
77952001279
-
Functional repair of human donor lungs by IL-10 gene therapy
-
Cypel, M., et al. 2009. Functional repair of human donor lungs by IL-10 gene therapy. Sci. Transl. Med. 1:4ra9.
-
(2009)
Sci. Transl. Med.
, vol.1
-
-
Cypel, M.1
-
9
-
-
1842859786
-
Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system
-
Das Sarma, J., E. Scheen, S. H. Seo, M. Koval, and S. R. Weiss. 2002. Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system. J. Neurovirol. 8:381-391.
-
(2002)
J. Neurovirol.
, vol.8
, pp. 381-391
-
-
Das Sarma, J.1
Scheen, E.2
Seo, S.H.3
Koval, M.4
Weiss, S.R.5
-
10
-
-
4644254400
-
IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8 CTL in tuberculosis patients
-
de la Barrera, S., et al. 2004. IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8 CTL in tuberculosis patients. Clin. Exp. Immunol. 138:128-138.
-
(2004)
Clin. Exp. Immunol.
, vol.138
, pp. 128-138
-
-
de la Barrera, S.1
-
11
-
-
43349089087
-
Prolongation of heart allograft survival after long-term expression of soluble MHC class I antigens and vIL-10 in the liver by AAV-plasmidmediated gene transfer
-
Doenecke, A., E. Frank, M. N. Scherer, H. J. Schlitt, and E. K. Geissler. 2008. Prolongation of heart allograft survival after long-term expression of soluble MHC class I antigens and vIL-10 in the liver by AAV-plasmidmediated gene transfer. Langenbecks Arch. Surg. 393:343-348.
-
(2008)
Langenbecks Arch. Surg.
, vol.393
, pp. 343-348
-
-
Doenecke, A.1
Frank, E.2
Scherer, M.N.3
Schlitt, H.J.4
Geissler, E.K.5
-
12
-
-
33750530611
-
Resolution of a chronic viral infection after interleukin-10 receptor blockade
-
Ejrnaes, M., et al. 2006. Resolution of a chronic viral infection after interleukin-10 receptor blockade. J. Exp. Med. 203:2461-2472.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2461-2472
-
-
Ejrnaes, M.1
-
13
-
-
0022446017
-
Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies
-
Fleming, J. O., M. D. Trousdale, F. A. el-Zaatari, S. A. Stohlman, and L. P. Weiner. 1986. Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies. J. Virol. 58:869-875.
-
(1986)
J. Virol.
, vol.58
, pp. 869-875
-
-
Fleming, J.O.1
Trousdale, M.D.2
El-Zaatari, F.A.3
Stohlman, S.A.4
Weiner, L.P.5
-
14
-
-
1242296998
-
IkappaB kinase is a critical regulator of chemokine expression and lung inflammation in respiratory syncytial virus infection
-
Haeberle, H. A., et al. 2004. IkappaB kinase is a critical regulator of chemokine expression and lung inflammation in respiratory syncytial virus infection. J. Virol. 78:2232-2241.
-
(2004)
J. Virol.
, vol.78
, pp. 2232-2241
-
-
Haeberle, H.A.1
-
15
-
-
66149158158
-
Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control
-
Kapil, P., et al. 2009. Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control. J. Virol. 83:5978-5986.
-
(2009)
J. Virol.
, vol.83
, pp. 5978-5986
-
-
Kapil, P.1
-
16
-
-
43049175169
-
Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis
-
Kaplan, D. E., et al. 2008. Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis. J. Hepatol. 48:903-913.
-
(2008)
J. Hepatol.
, vol.48
, pp. 903-913
-
-
Kaplan, D.E.1
-
17
-
-
0041633855
-
Protection against CTL escape and clinical disease in a murine model of virus persistence
-
Kim, T. S., and S. Perlman. 2003. Protection against CTL escape and clinical disease in a murine model of virus persistence. J. Immunol. 171:2006-2013.
-
(2003)
J. Immunol.
, vol.171
, pp. 2006-2013
-
-
Kim, T.S.1
Perlman, S.2
-
18
-
-
18744390313
-
-/- mice infected with a neurotropic coronavirus
-
-/- mice infected with a neurotropic coronavirus. J. Virol. 79:7113-7120.
-
(2005)
J. Virol.
, vol.79
, pp. 7113-7120
-
-
Kim, T.S.1
Perlman, S.2
-
19
-
-
53749103238
-
Viral IL-10 gene transfer prolongs rat islet allograft survival
-
Kim, Y. H., et al. 2008. Viral IL-10 gene transfer prolongs rat islet allograft survival. Cell Transplant. 17:609-618.
-
(2008)
Cell Transplant
, vol.17
, pp. 609-618
-
-
Kim, Y.H.1
-
20
-
-
0031590672
-
Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood
-
Kruse, N., M. Pette, K. Toyka, and P. Rieckmann. 1997. Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood. J. Immunol. Methods 210:195-203.
-
(1997)
J. Immunol. Methods
, vol.210
, pp. 195-203
-
-
Kruse, N.1
Pette, M.2
Toyka, K.3
Rieckmann, P.4
-
21
-
-
0033982337
-
Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrier
-
Kuo, L., G. J. Godeke, M. J. Raamsman, P. S. Masters, and P. J. Rottier. 2000. Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrier. J. Virol. 74:1393-1406.
-
(2000)
J. Virol.
, vol.74
, pp. 1393-1406
-
-
Kuo, L.1
Godeke, G.J.2
Raamsman, M.J.3
Masters, P.S.4
Rottier, P.J.5
-
22
-
-
0027361744
-
Effects of virally expressed interleukin-10 on vaccinia virus infection in mice
-
Kurilla, M. G., S. Swaminathan, R. M. Welsh, E. Kieff, and R. R. Brutkiewicz. 1993. Effects of virally expressed interleukin-10 on vaccinia virus infection in mice. J. Virol. 67:7623-7628.
-
(1993)
J. Virol.
, vol.67
, pp. 7623-7628
-
-
Kurilla, M.G.1
Swaminathan, S.2
Welsh, R.M.3
Kieff, E.4
Brutkiewicz, R.R.5
-
23
-
-
70449377991
-
Tregs control the development of symptomatic West Nile virus infection in humans and mice
-
Lanteri, M. C., et al. 2009. Tregs control the development of symptomatic West Nile virus infection in humans and mice. J. Clin. Invest. 119:3266-3277.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3266-3277
-
-
Lanteri, M.C.1
-
24
-
-
44849110730
-
Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells
-
Lau, A. W., S. Biester, R. J. Cornall, and J. V. Forrester. 2008. Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells. J. Immunol. 180:3889-3899.
-
(2008)
J. Immunol.
, vol.180
, pp. 3889-3899
-
-
Lau, A.W.1
Biester, S.2
Cornall, R.J.3
Forrester, J.V.4
-
25
-
-
77955138841
-
Induction of lymphocyte apoptosis in rat liver allograft by adenoviral gene transfection of human interleukin-10
-
Li, J. Q., et al. 2010. Induction of lymphocyte apoptosis in rat liver allograft by adenoviral gene transfection of human interleukin-10. Eur. Surg. Res. 44:133-141.
-
(2010)
Eur. Surg. Res.
, vol.44
, pp. 133-141
-
-
Li, J.Q.1
-
26
-
-
0028029793
-
IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity
-
Li, L., J. F. Elliott, and T. R. Mosmann. 1994. IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity. J. Immunol. 153:3967-3978.
-
(1994)
J. Immunol.
, vol.153
, pp. 3967-3978
-
-
Li, L.1
Elliott, J.F.2
Mosmann, T.R.3
-
27
-
-
0032486280
-
The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis
-
Lin, M. T., D. R. Hinton, B. Parra, S. A. Stohlman, and R. C. van der Veen. 1998. The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis. Virology 245:270-280.
-
(1998)
Virology
, vol.245
, pp. 270-280
-
-
Lin, M.T.1
Hinton, D.R.2
Parra, B.3
Stohlman, S.A.4
van der Veen, R.C.5
-
28
-
-
0035478591
-
Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis
-
Liu, M. T., H. S. Keirstead, and T. E. Lane. 2001. Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis. J. Immunol. 167:4091-4097.
-
(2001)
J. Immunol.
, vol.167
, pp. 4091-4097
-
-
Liu, M.T.1
Keirstead, H.S.2
Lane, T.E.3
-
29
-
-
0033258372
-
Reverse genetics of the largest RNA viruses
-
Masters, P. S. 1999. Reverse genetics of the largest RNA viruses. Adv. Virus Res. 53:245-264.
-
(1999)
Adv. Virus Res.
, vol.53
, pp. 245-264
-
-
Masters, P.S.1
-
30
-
-
67649226607
-
IL-10 deficiency unleashes an influenzaspecific Th17 response and enhances survival against high-dose challenge
-
McKinstry, K. K., et al. 2009. IL-10 deficiency unleashes an influenzaspecific Th17 response and enhances survival against high-dose challenge. J. Immunol. 182:7353-7363.
-
(2009)
J. Immunol.
, vol.182
, pp. 7353-7363
-
-
McKinstry, K.K.1
-
31
-
-
55149094739
-
Interleukin-10: new perspectives on an old cytokine
-
Mosser, D. M., and X. Zhang. 2008. Interleukin-10: new perspectives on an old cytokine. Immunol. Rev. 226:205-218.
-
(2008)
Immunol. Rev.
, vol.226
, pp. 205-218
-
-
Mosser, D.M.1
Zhang, X.2
-
32
-
-
60449107858
-
-/--dependent allergy mouse model
-
-/--dependent allergy mouse model. Gene Ther. 16:172-183.
-
(2009)
Gene Ther
, vol.16
, pp. 172-183
-
-
Mueller, C.1
-
33
-
-
57449102542
-
IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro
-
Muller, R. D., et al. 2008. IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro. Cytokine 44:377-385.
-
(2008)
Cytokine
, vol.44
, pp. 377-385
-
-
Muller, R.D.1
-
34
-
-
70350464351
-
Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
-
Murai, M., et al. 2009. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat. Immunol. 10:1178-1184.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1178-1184
-
-
Murai, M.1
-
35
-
-
0141856400
-
Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein
-
Ontiveros, E., T. S. Kim, T. M. Gallagher, and S. Perlman. 2003. Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein. J. Virol. 77:10260-10269.
-
(2003)
J. Virol.
, vol.77
, pp. 10260-10269
-
-
Ontiveros, E.1
Kim, T.S.2
Gallagher, T.M.3
Perlman, S.4
-
36
-
-
77954541452
-
IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment
-
Palmer, E. M., B. C. Holbrook, S. Arimilli, G. D. Parks, and M. A. Alexander-Miller. 2010. IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment. Virology 404:225-230.
-
(2010)
Virology
, vol.404
, pp. 225-230
-
-
Palmer, E.M.1
Holbrook, B.C.2
Arimilli, S.3
Parks, G.D.4
Alexander-Miller, M.A.5
-
37
-
-
0031820378
-
Abundant IFN-gamma production by local T cells in respiratory syncytial virus-induced eosinophilic lung disease
-
Spender, L. C., T. Hussell, and P. J. Openshaw. 1998. Abundant IFN-gamma production by local T cells in respiratory syncytial virus-induced eosinophilic lung disease. J. Gen. Virol. 79(Part 7):1751-1758.
-
(1998)
J. Gen. Virol.
, vol.79
, Issue.PART 7
, pp. 1751-1758
-
-
Spender, L.C.1
Hussell, T.2
Openshaw, P.J.3
-
38
-
-
0000567323
-
Mouse hepatitis virus
-
In R. Ahmed and I. Chen (ed.). John Wiley & Sons, Ltd., New York, NY
-
Stohlman, S. A., C. C. Bergmann, and S. Perlman. 1998. Mouse hepatitis virus, p. 537-557. In R. Ahmed and I. Chen (ed.), Persistent viral infections. John Wiley & Sons, Ltd., New York, NY.
-
(1998)
Persistent viral infections
, pp. 537-557
-
-
Stohlman, S.A.1
Bergmann, C.C.2
Perlman, S.3
-
39
-
-
62049085168
-
Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10
-
Sun, J., R. Madan, C. L. Karp, and T. J. Braciale. 2009. Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat. Med. 15:277-284.
-
(2009)
Nat. Med.
, vol.15
, pp. 277-284
-
-
Sun, J.1
Madan, R.2
Karp, C.L.3
Braciale, T.J.4
-
40
-
-
77952746516
-
Regulatory T cells inhibit T cell proliferation and decrease demyelination in mice chronically infected with a coronavirus
-
Trandem, K., D. Anghelina, J. Zhao, and S. Perlman. 2010. Regulatory T cells inhibit T cell proliferation and decrease demyelination in mice chronically infected with a coronavirus. J. Immunol. 184:4391-4400.
-
(2010)
J. Immunol.
, vol.184
, pp. 4391-4400
-
-
Trandem, K.1
Anghelina, D.2
Zhao, J.3
Perlman, S.4
-
41
-
-
79953222926
-
Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirusinduced encephalitis
-
Trandem, K., J. Zhao, E. Fleming, and S. Perlman. 2011. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirusinduced encephalitis. J. Immunol. 186:3642-3652.
-
(2011)
J. Immunol.
, vol.186
, pp. 3642-3652
-
-
Trandem, K.1
Zhao, J.2
Fleming, E.3
Perlman, S.4
-
42
-
-
0026710667
-
Sequential infection of glial cells by the murine hepatitis virus JHM strain (MHV-4) leads to a characteristic distribution of demyelination
-
Wang, F. I., D. R. Hinton, W. Gilmore, M. D. Trousdale, and J. O. Fleming. 1992. Sequential infection of glial cells by the murine hepatitis virus JHM strain (MHV-4) leads to a characteristic distribution of demyelination. Lab. Invest. 66:744-754.
-
(1992)
Lab. Invest.
, vol.66
, pp. 744-754
-
-
Wang, F.I.1
Hinton, D.R.2
Gilmore, W.3
Trousdale, M.D.4
Fleming, J.O.5
-
43
-
-
0025131909
-
Demyelination induced by murine hepatitis virus JHM strain (MHV-4) is immunologically mediated
-
Wang, F. I., S. A. Stohlman, and J. O. Fleming. 1990. Demyelination induced by murine hepatitis virus JHM strain (MHV-4) is immunologically mediated. J. Neuroimmunol. 30:31-41.
-
(1990)
J. Neuroimmunol.
, vol.30
, pp. 31-41
-
-
Wang, F.I.1
Stohlman, S.A.2
Fleming, J.O.3
-
44
-
-
22144487678
-
A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis
-
Wilson, E. H., U. Wille-Reece, F. Dzierszinski, and C. A. Hunter. 2005. A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. J. Neuroimmunol. 165:63-74.
-
(2005)
J. Neuroimmunol.
, vol.165
, pp. 63-74
-
-
Wilson, E.H.1
Wille-Reece, U.2
Dzierszinski, F.3
Hunter, C.A.4
-
45
-
-
0034664053
-
CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination
-
Wu, G. F., A. A. Dandekar, L. Pewe, and S. Perlman. 2000. CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. J. Immunol. 165:2278-2286.
-
(2000)
J. Immunol.
, vol.165
, pp. 2278-2286
-
-
Wu, G.F.1
Dandekar, A.A.2
Pewe, L.3
Perlman, S.4
-
46
-
-
0032813555
-
Depletion of bloodborne macrophages does not reduce demyelination in mice infected with a neurotropic coronavirus
-
Xue, S., N. Sun, N. Van Rooijen, and S. Perlman. 1999. Depletion of bloodborne macrophages does not reduce demyelination in mice infected with a neurotropic coronavirus. J. Virol. 73:6327-6334.
-
(1999)
J. Virol.
, vol.73
, pp. 6327-6334
-
-
Xue, S.1
Sun, N.2
Van Rooijen, N.3
Perlman, S.4
-
47
-
-
72849120756
-
Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis
-
Yang, J., et al. 2009. Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. J. Clin. Invest. 119:3678-3691.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3678-3691
-
-
Yang, J.1
-
48
-
-
77950799203
-
De novo recruitment of antigenexperienced and naive T cells contributes to the long-term maintenance of antiviral T cell populations in the persistently infected central nervous system
-
Zhao, J., J. Zhao, and S. Perlman. 2009. De novo recruitment of antigenexperienced and naive T cells contributes to the long-term maintenance of antiviral T cell populations in the persistently infected central nervous system. J. Immunol. 183:5163-5170.
-
(2009)
J. Immunol.
, vol.183
, pp. 5163-5170
-
-
Zhao, J.1
Zhao, J.2
Perlman, S.3
|