Migrational guidance of neutrophils is mechanotransduced via high-affinity LFA-1 and calcium flux

Journal of Immunology

Volumn 187, Issue 1, 2011, Pages 472-481

  Dixit, Neha ^a,b   Yamayoshi, Itsukyo ^a   Nazarian, Ari ^a   Simon, Scott I ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; F ACTIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY;

ARTICLE; BINDING AFFINITY; BLOOD FLOW; CALCIUM TRANSPORT; CELL ACTIVATION; CELL MIGRATION; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; LEUKOCYTE MIGRATION; MECHANOTRANSDUCTION; POLARIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN POLYMERIZATION; SHEAR STRESS; SIGNAL TRANSDUCTION;

ACTINS; ADULT; ANIMALS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL ADHESION; CELL MOVEMENT; CELL POLARITY; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; NEUTROPHILS; PROTEIN BINDING;

EID: 79960392811     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1004197     Document Type: Article

References (36)

1. Evans, E., A. Leung, D. Hammer, and S. Simon. 2001. Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force. Proc. Natl. Acad. Sci. USA 98: 3784-3789.
2. Simon, S. I., Y. Hu, D. Vestweber, and C. W. Smith. 2000. Neutrophil tethering on E-selectin activates b2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway. J. Immunol. 164: 4348-4358.
3. Alon, R., and M. L. Dustin. 2007. Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity 26: 17-27.
4. Green, C. E., U. Y. Schaff, M. R. Sarantos, A. F. Lum, D. E. Staunton, and S. I. Simon. 2006. Dynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium. Blood 107: 2101-2111.
5. 2 integrin adhesive and signaling events that guide inflammatory recruitment. Ann. Biomed. Eng. 36: 632-646.
6. Schreiber, T. H., V. Shinder, D. W. Cain, R. Alon, and R. Sackstein. 2007. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. Blood 109: 1381-1386. (Pubitemid 46239568)
7. Phillipson, M., B. Heit, S. A. Parsons, B. Petri, S. C. Mullaly, P. Colarusso, R. M. Gower, G. Neely, S. I. Simon, and P. Kubes. 2009. Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature. J. Immunol. 182: 6870-6878.
8. Schaff, U. Y., N. Dixit, E. Procyk, I. Yamayoshi, T. Tse, and S. I. Simon. 2010. Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow. Blood 115: 657-666.
9. Sjaastad, M. D., and W. J. Nelson. 1997. Integrin-mediated calcium signaling and regulation of cell adhesion by intracellular calcium. Bioessays 19: 47-55.
10. Krause, K. H., K. P. Campbell, M. J. Welsh, and D. P. Lew. 1990. The calcium signal and neutrophil activation. Clin. Biochem. 23: 159-166.
11. Shen, J., F.W. Luscinskas, A. Connolly, C. F. Dewey, Jr., and M. A. Gimbrone Jr. 1992. Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells. Am. J. Physiol. 262: C384-C390.
12. Sarantos, M. R., S. Raychaudhuri, A. F. Lum, D. E. Staunton, and S. I. Simon. 2005. Leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular adhesion molecule-1. J. Biol. Chem. 280: 28290-28298.
13. Jun, C. D., M. Shimaoka, C. V. Carman, J. Takagi, and T. A. Springer. 2001. Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion. Proc. Natl. Acad. Sci. USA 98: 6830-6835.
14. Miller, J., R. Knorr, M. Ferrone, R. Houdei, C. P. Carron, and M. L. Dustin. 1995. Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1. J. Exp. Med. 182: 1231-1241.
15. Sarantos, M. R., H. Zhang, U. Y. Schaff, N. Dixit, H. N. Hayenga, C. A. Lowell, and S. I. Simon. 2008. Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase. J. Immunol. 181: 8660-8669.
16. 2 integrin-dependent functions of neutrophils. J. Cell Biol. 166: 273-282.
17. Puklin-Faucher, E., and M. P. Sheetz. 2009. The mechanical integrin cycle. J. Cell Sci. 122: 179-186.
18. Feske, S., Y. Gwack, M. Prakriya, S. Srikanth, S. H. Puppel, B. Tanasa, P. G. Hogan, R. S. Lewis, M. Daly, and A. Rao. 2006. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441: 179-185.
19. 2+ entry and NFAT activation in lymphocytes. Cell Calcium 42: 145-156.
20. Lowell, C. A., L. Fumagalli, and G. Berton. 1996. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. J. Cell Biol. 133: 895-910.
21. Mitchon, L. N., and J. M. White. 2006. Growth and analysis of octadecylsiloxane monolayers on Al2O3 (0001). Langmuir 22: 6549-6554.
22. Schaff, U. Y., M. M. Xing, K. K. Lin, N. Pan, N. L. Jeon, and S. I. Simon. 2007. Vascular mimetics based on microfluidics for imaging the leukocyte: endothelial inflammatory response. Lab Chip 7: 448-456.
23. 2 subunit requires association with the a subunit. Proc. Natl. Acad. Sci. USA 94: 3156-3161.
24. Lum, A. F., C. E. Green, G. R. Lee, D. E. Staunton, and S. I. Simon. 2002. Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow. J. Biol. Chem. 277: 20660-20670.
25. Shulman, Z., V. Shinder, E. Klein, V. Grabovsky, O. Yeger, E. Geron, A. Montresor, M. Bolomini-Vittori, S. W. Feigelson, T. Kirchhausen, et al. 2009. Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. Immunity 30: 384-396.
26. 2+ entry in the immune system and beyond. Immunol. Rev. 231: 189-209.
27. 2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes. Cell Calcium 44: 492-506.
28. McMeekin, S. R., I. Dransfield, A. G. Rossi, C. Haslett, and T. R. Walker. 2006. E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils. Blood 107: 4938-4945.
29. Heiner, I., J. Eisfeld, C. R. Halaszovich, E. Wehage, E. Jüngling, C. Zitt, and A. Lückhoff. 2003. Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD. Biochem. J. 371: 1045-1053. (Pubitemid 36578904)
30. Pasvolsky, R., S. W. Feigelson, S. S. Kilic, A. J. Simon, G. Tal-Lapidot, V. Grabovsky, J. R. Crittenden, N. Amariglio, M. Safran, A. M. Graybiel, et al. 2007. A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets. J. Exp. Med. 204: 1571-1582.
31. Mory, A., S. W. Feigelson, N. Yarali, S. S. Kilic, G. I. Bayhan, R. Gershoni-Baruch, A. Etzioni, and R. Alon. 2008. Kindlin-3: a new gene involved in the pathogenesis of LAD-III. Blood 112: 2591.
32. Kitayama, J., A. Hidemura, H. Saito, and H. Nagawa. 2000. Shear stress affects migration behavior of polymorphonuclear cells arrested on endothelium. Cell. Immunol. 203: 39-46.
33. Ambravaneswaran, V., I. Y. Wong, A. J. Aranyosi, M. Toner, and D. Irimia. 2010. Directional decisions during neutrophil chemotaxis inside bifurcating channels. Integr. Biol. (Camb.) 2: 639-647.
34. Porter, J. C., M. Bracke, A. Smith, D. Davies, and N. Hogg. 2002. Signaling through integrin LFA-1 leads to filamentous actin polymerization and remodeling, resulting in enhanced T cell adhesion. J. Immunol. 168: 6330-6335. (Pubitemid 34620055)
35. Yang, S., J. J. Zhang, and X. Y. Huang. 2009. Orai1 and STIM1 are critical for breast tumor cell migration and metastasis. Cancer Cell 15: 124-134.
36. Lioudyno, M. I., J. A. Kozak, A. Penna, O. Safrina, S. L. Zhang, D. Sen, J. Roos, K. A. Stauderman, and M. D. Cahalan. 2008. Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation. Proc. Natl. Acad. Sci. USA 105: 2011-2016.