Use of different molecular typing methods for the study of heterogeneity within Clostridium difficile toxinotypes V and III

Journal of Medical Microbiology

Volumn 60, Issue 8, 2011, Pages 1101-1107

  Janezic, S ^a   Indra, A ^b   Allerberger, F ^b   Rupnik, M ^a,c  

^a Centre for Microbiology   (Slovenia)

^b AUSTRIAN AGENCY FOR HEALTH AND FOOD SAFETY   (Austria)

^c UNIVERSITY OF MARIBOR   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME;

AGAR GEL ELECTROPHORESIS; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE TOXINOTYPE III; CLOSTRIDIUM DIFFICILE TOXINOTYPE V; COMPARATIVE STUDY; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; GEL ELECTROPHORESIS; GENETIC HETEROGENEITY; HUMAN; MOLECULAR TYPING; NONHUMAN; PRIORITY JOURNAL; RIBOTYPING; SWINE;

CLOSTRIDIUM DIFFICILE; ELECTROPHORESIS, AGAR GEL; GENETIC VARIATION; HUMANS; MOLECULAR TYPING; POLYMERASE CHAIN REACTION; RIBOTYPING;

EID: 79960387111     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.031054-0     Document Type: Article

References (34)

1. Avbersek, J., Janezic, S., Pate, M., Rupnik, M., Zidaric, V., Logar, K., Vengust, M., Zemljic, M., Pirs, T. & Ocepek, M. (2009). Diversity of Clostridium difficile in pigs and other animals in Slovenia. Anaerobe 15, 252-255.
2. Bakker, D., Corver, J., Harmanus, C., Goorhuis, A., Keessen, E. C., Fawley, W. N., Wilcox, M. H. & Kuijper, E. J. (2010). Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance. J Clin Microbiol 48, 3744-3749.
3. Baldan, R., Cavallerio, P., Tuscano, A., Parlato, C., Fossati, L., Moro, M., Serra, R. & Cirillo, D. M. (2010). First report of hypervirulent strains polymerase chain reaction ribotypes 027 and 078 causing severe Clostridium difficile infection in Italy. Clin Infect Dis 50, 126-127.
4. Barbut, F., Mastrantonio, P., Delme ́e, M., Brazier, J., Kuijper, E., Poxton, I. on behalf of the European Study Group on Clostridium difficile (ESGCD) (2007). Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterization of the isolates. Clin Microbiol Infect 13, 1048-1057.
5. Bauer, M. P., Notermans, D. W., van Benthem, B. H., Brazier, J. S., Wilcox, M. H., Rupnik, M., Monnet, D. L., van Dissel, J. T., Kuijper, E. J. for the ECDIS Study Group (2011). Clostridium difficile infection in Europe: a hospital-based survey. Lancet 377, 63-73.
6. Bidet, P., Barbut, F., Lalande, V., Burghoffer, B. & Petit, J. C. (1999). Development of a new PCR-ribotyping method for Clostridium difficile based on ribosomal RNA gene sequencing. FEMS Microbiol Lett 175, 261-266.
7. Drudy, D., Goorhuis, B., Bakker, D., Kyne, L., van den Berg, R., Fenelon, L., Fanning, S. & Kuijper, E. J. (2008). Clindamycin-resistant clone of Clostridium difficile PCR ribotype 027, Europe. Emerg Infect Dis 14, 1485-1487.
8. Fawley, W. N., Freeman, J., Smith, C., Harmanus, C., van den Berg, R. J., Kuijper, E. J. & Wilcox, M. H. (2008). Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains. J Clin Microbiol 46, 954-960.
9. Goorhuis, A., Bakker, D., Corver, J., Debast, S. B., Harmanus, C., Notermans, D. W., Bergwerff, A. A., Dekker, F. W. & Kuijper, E. J. (2008). Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078. Clin Infect Dis 47, 1162-1170.
10. Gould, L. H. & Limbago, B. (2010). Clostridium difficile in food and domestic animals: a new foodborne pathogen? Clin Infect Dis 51, 577-582.
11. Griffiths, D., Fawley, W., Kachrimanidou, M., Bowden, R., Crook, D. W., Fung, R., Golubchik, T., Harding, R. M., Jeffery, K. J. & other authors (2010). Multilocus sequence typing of Clostridium difficile. J Clin Microbiol 48, 770-778.
12. He, M., Sebaihia, M., Lawley, T. D., Stabler, R. A., Dawson, L. F., Martin, M. J., Holt, K. E., Seth-Smith, H. M., Quail, M. A. & other authors (2010). Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci U S A 107, 7527-7532.
13. Indra, A., Huhulescu, S., Schneeweis, M., Hasenberger, P., Kernbichler, S., Fiedler, A., Wewalka, G., Allerberger, F. & Kuijper, E. J. (2008). Characterization of Clostridium difficile isolates using capillary gel electrophoresis-based PCR ribotyping. J Med Microbiol 57, 1377-1382.
14. Janezic, S. & Rupnik, M. (2010). Molecular typing methods for Clostridium difficile: pulsed-field gel electrophoresis and PCR ribotyping. Methods Mol Biol 646, 55-65.
15. Jhung, M. A., Thompson, A. D., Killgore, G. E., Zukowski, W. E., Songer, G., Warny, M., Johnson, S., Gerding, D. N., McDonald, L. C. & Limbago, B. M. (2008). Toxinotype V Clostridium difficile in humans and food animals. Emerg Infect Dis 14, 1039-1045.
16. Kato, H., Kato, N., Watanabe, K., Ueno, K., Ushijima, H., Hashira, S. & Abe, T. (1994). Application of typing by pulsed-field gel electrophoresis to the study of Clostridium difficile in a neonatal intensive care unit. J Clin Microbiol 32, 2067-2070.
17. Kato, H., Kato, N., Watanabe, K., Iwai, N., Nakamura, H., Yamamoto, T., Suzuki, K., Kim, S.-M., Chong, Y. & Wasito, E. B. (1998). Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR. J Clin Microbiol 36, 2178-2182.
18. Keel, K., Brazier, J. S., Post, K. W., Weese, S. & Songer, J. G. (2007). Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species. J Clin Microbiol 45, 1963-1964.
19. Killgore, G., Thompson, A., Johnson, S., Brazier, J., Kuijper, E., Pepin, J., Frost, E. H., Savelkoul, P., Nicholson, B. & other authors (2008). Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. J Clin Microbiol 46, 431-437.
20. Kuijper, E. J., Coignard, B., Tüll, P., ESCMID Study Group for Clostridium difficile (ESGCD), EU Member States & European Centre for Disease Prevention and Control (ECDC) (2006). Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect 12 (Suppl. 6), 2-18.
21. Limbago, B. M., Long, C. M., Thompson, A. D., Killgore, G. E., Hannett, G. E., Havill, N. L., Mickelson, S., Lathrop, S., Jones, T. F. & other authors (2009). Clostridium difficile strains from communityassociated infections. J Clin Microbiol 47, 3004-3007.
22. Marsh, J. W., O'Leary, M. M., Shutt, K. A., Sambol, S. P., Johnson, S., Gerding, D. N. & Harrison, L. H. (2010). Multilocus variable-number tandem-repeat analysis and multilocus sequence typing reveal genetic relationships among Clostridium difficile isolates genotyped by restriction endonuclease analysis. J Clin Microbiol 48, 412-418.
23. McDonald, L. C., Killgore, G. E., Thompson, A., Owens, R. C., Jr, Kazakova, S. V., Sambol, S. P., Johnson, S. & Gerding, D. N. (2005). An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med 353, 2433-2441.
24. Rodriguez-Palacios, A., Stämpfli, H. R., Duffield, T., Peregrine, A. S., Trotz-Williams, L. A., Arroyo, L. G., Brazier, J. S. & Weese, J. S. (2006). Clostridium difficile PCR ribotypes in calves, Canada. Emerg Infect Dis 12, 1730-1736.
25. Rupnik, M. (2008). Heterogeneity of large clostridial toxins: importance of Clostridium difficile toxinotypes. FEMS Microbiol Rev 32, 541-555.
26. Rupnik, M., Avesani, V., Janc, M., von Eichel-Streiber, C. & Delme ́e, M. (1998). A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol 36, 2240-2247.
27. Rupnik, M., Brazier, J. S., Duerden, B. I., Grabnar, M. & Stubbs, S. L. (2001). Comparison of toxinotyping and PCR ribotyping of Clostridium difficile strains and description of novel toxinotypes. Microbiology 147, 439-447.
28. Rupnik, M., Widmer, A., Zimmermann, O., Eckert, C. & Barbut, F. (2008). Clostridium difficile toxinotype V, ribotype 078, in animals and humans. J Clin Microbiol 46, 2146.
29. Rupnik, M., Wilcox, M. H. & Gerding, D. N. (2009). Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nat Rev Microbiol 7, 526-536.
30. Stabler, R. A., Gerding, D. N., Songer, J. G., Drudy, D., Brazier, J. S., Trinh, H. T., Witney, A. A., Hinds, J. & Wren, B. W. (2006). Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. J Bacteriol 188, 7297-7305.
31. Stabler, R. A., He, M., Dawson, L., Martin, M., Valiente, E., Corton, C., Lawley, T. D., Sebaihia, M., Quail, M. A. & other authors (2009). Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol 10, R102.
32. Stubbs, S., Rupnik, M., Gibert, M., Brazier, J., Duerden, B. & Popoff, M. (2000). Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile. FEMS Microbiol Lett 186, 307-312.
33. Tenover, F. C., Arbeit, R. D., Goering, R. V., Mickelsen, P. A., Murray, B. E., Persing, D. H. & Swaminathan, B. (1995). Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33, 2233-2239.
34. Weese, J. S. (2010). Clostridium difficile in food - innocent bystander or serious threat? Clin Microbiol Infect 16, 3-10.